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Post-operative Pain clinical trials

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NCT ID: NCT06380140 Recruiting - Post Operative Pain Clinical Trials

Relationship Between Acute Phase Markers and Post-operative Pain in Open Tension-free Inguinal Hernia Repair: An Observational Study

Start date: May 3, 2023
Phase:
Study type: Observational

Many patients undergoing inguinal hernia repair are prone to developing acute and chronic post-operative pain. The aim of the study is to show a possible correlation between pain and acute phase proteins in order to: - predict the severity of pain; - select most suitable pain relief therapy for the patient.

NCT ID: NCT06375057 Recruiting - Post Operative Pain Clinical Trials

Relationship Between Acute Phase Markers and Post-operative Pain in Laparoscopic Cholecystectomy: An Observational Study

Start date: March 3, 2023
Phase:
Study type: Observational

Many patients undergoing laparoscopic cholecystectomy are prone to developing acute and chronic post-operative pain. The aim of the study is to show a possible correlation between pain and acute phase proteins in order to: - predict the severity of pain; - select most suitable pain relief therapy for the patient.

NCT ID: NCT06331793 Recruiting - Post Operative Pain Clinical Trials

Pulsed Electromagnetic Fields for Analgesia Post Mastectomy

Algocare
Start date: May 9, 2023
Phase: N/A
Study type: Interventional

Study aim is to test AlgoCare, a device that uses the technology PEMF (Pulsed ElectroMagnetic Fields) for the treatment of postoperative pain in oncological breast surgery, in order to demonstrate that the use of Algocare in the postoperative period allows for a reduction in pain intensity in terms of Numerical Rating Scale (NRS) score and use of analgesic drugs.

NCT ID: NCT06315959 Recruiting - Chronic Pain Clinical Trials

Bilateral Erector Spinae Plane Block for Postoperative Chronic Pain After Open Heart Surgery

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effect of bilateral erector spinae plane (ESP) block application on postoperative chronic pain in patients undergoing on-pump open-heart surgery. At 3 months post-discharge, patients will be contacted by phone to assess their chronic pain status. Pain intensity and status will be evaluated using the Brief Pain Inventory, and the character of pain will be assessed using the Douleur Neuropathique 4 (DN4) score. Additionally, the patient's anxiety and depression status will be evaluated using the Hospital Anxiety and Depression Scale.

NCT ID: NCT06294665 Recruiting - Hip Fractures Clinical Trials

Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block

Start date: March 1, 2024
Phase: Phase 1
Study type: Interventional

The aim of this work is to compare the effectiveness of bupivacaine- dexmedetomidine mixture versus bupivacaine-dexamethasone mixture in PENG Block as Post-operative Analgesia in Hip surgeries

NCT ID: NCT06281418 Recruiting - Post Operative Pain Clinical Trials

Postoperative Intraperitoneal Pain Management Following Laparoscopic Cholecystectomy

Start date: February 29, 2024
Phase: Phase 3
Study type: Interventional

Postoperative pain management is essential and the inability to treat acute pain appropriately in the first 48 postoperative hours represents a risk factor for developing chronic pain. No. study has investigated IP granisetron as an adjuvant to standard care for postoperative pain management in patients undergoing LC.

NCT ID: NCT06269770 Recruiting - Chronic Pain Clinical Trials

Tapentadol vs Tramadol in Total Knee Arthroplasty

Start date: May 1, 2023
Phase: Phase 4
Study type: Interventional

Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Total Knee Replacement (TKR).

NCT ID: NCT06258239 Recruiting - Post-operative Pain Clinical Trials

Influence of the Communication Between the Nursing Staff and the Patient on the Analgesic Treatment Effectiveness After Surgery

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Acute pain is a normal response to tissue injury or disease and has an important biological function. It is adaptive and promotes recuperation by restricting behaviors that might incur further tissue trauma. In the case of post-operative acute pain, the cause and time of the physical injury are known, and because the condition is self-limiting it requires only short-term care. However, if acute pain responses cannot be adequately suppressed, cardiac, pulmonary and neuroendocrine functions may be compromised, and the immune system suppressed. Inadequate management of post-operative acute pain is a major burden for healthcare services and can contribute to medical complications including inflammation of the respiratory tract, damage to the oxygen supply to the heart muscle, deep vein thrombosis, delayed healing as well as the development of chronic pain, more difficult to treat. In addition, suboptimal management of pain after surgery may impair sleep and have negative psychological effects, such as anxiety, fear and lack of sleep. Proper treatment of pain reduces morbidity, damages, treatment costs, improves the patient's quality of life and his chances of a full recovery. It is therefore essential that all patients undergoing surgery should receive adequate pain management. Despite years of advances in pain management, the mainstay of postoperative pain therapy in many settings is still opioids. Morphine is the most commonly used opioid to treat moderate to severe pain after surgery in the recovery unit. The growing concern about the significant side effects, addictions and costs of opioids as a drug treatment has led to an urgent need to identify other agents and approaches to postoperative pain management that are effective, safe and cheap. The main purpose of this study is to examine whether the type of communication between the nursing staff and the patient will affect the results of pain relief treatment in the postoperative recovery department. As a secondary objective, we will examine whether personality traits will predict the effectiveness of the treatment.

NCT ID: NCT06216951 Recruiting - Post Operative Pain Clinical Trials

Post-Operative Pain After Vital Pulpotomy in Molars With Symptomatic Pulpitis

POPAVPT
Start date: December 15, 2021
Phase:
Study type: Observational

The goal of this clinical trial is to investigate post-operative pain (PEP) in teeth with symptomatic pulpitis following Vital Pulpotomy Treatments (VPT) with Calcium Silicate Cement (CSC). The main questions it aims to answer are: - Is the post-operative pain one week after VPT significantly lower than pre-operative pain in permanent molars with symptomatic pulpitis? - How does post-operative pain in these teeth correlate with patient-related factors, such as age, gender, and painkiller intake? Participants will: - Undergo Vital Pulpotomy Treatment with Calcium Silicate Cement (MTA) - Provide pain level assessments before VPT, immediately post-treatment, and at 24, 72 hours, and 1 week after treatment. If there is a comparison group: Researchers will compare the post-operative pain levels in teeth with symptomatic pulpitis undergoing VPT to assess its effectiveness in reducing pain compared to a control group not undergoing the treatment.

NCT ID: NCT06215859 Recruiting - Pain Clinical Trials

Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Herniorrhaphy

Start date: December 29, 2023
Phase: Phase 3
Study type: Interventional

MR-107A-02 is being studied to investigate its efficacy and safety for treatment of acute pain after herniorrhaphy.