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Poor Glycemic Control clinical trials

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NCT ID: NCT06385899 Completed - Type 2 Diabetes Clinical Trials

Effect of Intensive Monitoring of Patients With Poorly Controlled Type 2 Diabetes With Different Glycemic Background

Start date: August 1, 2021
Phase:
Study type: Observational

In Turkey, only 55% of patients with type 2 diabetes have been diagnosed, and 91% of these patients have been receiving treatment. The rate of patients reaching the treatment target is 50%. The pandemic has also affected diabetic patients. It is aimed to determine the characteristics of patients with type 2 diabetes (HbA1c >=10) with poor metabolic control and to evaluate the extent to which metabolic control can be achieved in 12 months.

NCT ID: NCT06141629 Completed - Quality of Life Clinical Trials

Benefits of a Bolus Calculator in Pediatric Patients on Multiple Daily Insulin Injections

Start date: January 2015
Phase: N/A
Study type: Interventional

It it hypothesized that children and adolescents with type 1 diabetes, who are counting carbohydrates can achieve better metabolic control by concurrent use of the Accu-Chek Aviva Expert. Additionally, it is proposed that carbohydrate counting in combination with the the Accu-Chek Aviva Expert will lead to better quality of life as a result of fewer restrictions when eating and less variation in blood glucose.

NCT ID: NCT03805191 Recruiting - Clinical trials for Type 2 Diabetes Mellitus

A Study for Sufficient Acarbose Decreased Glucose Excursion in Type 2 Diabetic Patients

FLAT
Start date: January 1, 2019
Phase:
Study type: Observational

This is a multicentre observational study to investigate the improvement in glucose fluctuation of sufficient acarbose therapy on type 2 diabetes patient with high blood glucose fluctuation

NCT ID: NCT03616275 Completed - Prediabetes Clinical Trials

Enhancing the Vagal Tone in Prediabetes Individuals

Start date: October 17, 2017
Phase: N/A
Study type: Interventional

This is a 2-year course of study. A randomized control trial will be conducted, in which 90 prediabetes individuals will be recruited and randomly assigned them into the wait-list control group or experimental group to test the effectiveness of 8 once-a-week, individual, 20-min sessions of HRV biofeedback on modulating vagal tone, glycemic control, psychological wellbeing, and inflammatory status in this population. Its longitudinal effects will be evaluated after 3- and 6-month follow-up.

NCT ID: NCT02917928 Recruiting - Clinical trials for Cardiovascular Risk Factors

The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health

Start date: October 2016
Phase: Phase 2
Study type: Interventional

The investigators hypothesise that carnosine supplementation will improve: 1. glycaemic control 2. cardiovascular risk factors 3. cognitive outcomes in patients with prediabetes and type 2 diabetes, and this will be modulated by reduction in chronic low grade inflammation, oxidative stress and circulating advanced glycation end products levels. 3. Aims To determine the potential of carnosine supplementation for 14 weeks to improve glycaemic control in type 2 diabetes, reduce risk factors for cardiovascular disease and improve cognitive function as well as identify metabolic pathways involved, specifically by: 1. Improving glycaemic control (HBA1c, fasting and 2 hour glucose and glucose area under the curve after oral glucose tolerance test) 2. Reducing cardiovascular risk factors (lipids; arterial (aortic) stiffness; central blood pressure (cBP); endothelial function). 3. Improve cognitive function (global cognitive score formed by a composite of 4 cognitive tests) 4. Decrease the chronic low grade inflammation, oxidative stress, advanced glycation end products, and advanced lipoxidation end products, and increase detoxification of reactive carbonyl species (RCSs).

NCT ID: NCT02876029 Completed - Clinical trials for Poor Glycemic Control

Food Design for Improved Day-long Glycaemic Regulation

Start date: September 2014
Phase: N/A
Study type: Interventional

The study focus is on the possible improvement in glucose tolerance at a second standardized meal that can be achieved when preceded by a test meal with a low GI and a high GP.

NCT ID: NCT02614729 Completed - Obesity Clinical Trials

The Consumption of Beef on Appetite and Cognitive Function

Start date: January 2014
Phase: N/A
Study type: Interventional

The purpose of the main study is to determine whether the daily consumption of protein-rich meals containing high quality, lean beef products improves appetite control and cognitive function during a weight maintenance diet. The purpose of the sub-study is to determine whether the daily consumption of protein-rich meals containing the same amount of high quality, lean beef products improves appetite control and cognitive function during a modest energy restriction, weight loss diet.

NCT ID: NCT02248272 Completed - Hyperglycemia Clinical Trials

Effect of Meal Frequency on Glycemic Control of People at High Risk or Diagnosed With Diabetes

Start date: October 2011
Phase: N/A
Study type: Interventional

This study investigated any potential associations between two isocaloric diets with different meal frequency (3 meals versus 6 meals) and glycemic control in people at high diabetes risk (lean and overweight/obese women with PCOS, individuals with hyperinsulinemia, individuals with impaired glucose tolerance) and diagnosed with diabetes.

NCT ID: NCT01792830 Completed - Clinical trials for Poor Glycemic Control

Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Coronary Artery Bypass Graft (CABG) Patients

CABG-D/C
Start date: October 2012
Phase: Phase 3
Study type: Interventional

Most coronary artery bypass graft surgery (CABG) patients develop high blood sugar while they are in the hospital. No studies have shown what the best insulin regimen is for CABG patients with type 2 diabetes is after going home from the hospital. Patients with high blood sugar and diabetes after cardiac bypass surgery will be followed for 3 months to look at how well their treatment(s) for diabetes work after discharge. Patients with diabetes will be discharged on oral antidiabetic drugs or with insulin glargine injections based on their sugar control. Patients with admission HbA1c < 7% (a laboratory value that shows the average blood sugar level in the body over 3 months) will be discharged on the same diabetes medications that they used before coming to the hospital. Those with an HbA1c between 7% and 9% will be discharged on insulin glargine at 50%-80% of the dose used in the hospital and oral antidiabetic drugs. Those with an HbA1c > 9% will be discharged on glargine at 80-100% of the dose used in the hospital in addition to oral antidiabetic drugs or with insulin glargine and insulin glulisine. The primary outcome will be a change in HbA1c at 4 and 12 weeks after discharge.

NCT ID: NCT01688778 Completed - Type 2 Diabetes Clinical Trials

Telemedicine as a Means to Achieving Good Diabetes Control Among Patients With Type 2 Diabetes

Start date: June 2012
Phase: N/A
Study type: Interventional

The aim of the study is to investigate the effect of telemedicine among the group of type-2-diabetics who, despite rehabilitation, remain poorly regulated. To describe the patients with regards to vulnerability and social resources and to determine wich groups benefit the most from telemedicine.