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Polycystic Ovary Syndrome clinical trials

View clinical trials related to Polycystic Ovary Syndrome.

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NCT ID: NCT04744948 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Effect Of Treadmill Based Aerobic Exercise Intervention On Menstruation And Quality Of Life In Women With Polycystic Ovarian Syndrome

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

this study will be carried to investigate the effect of aerobic exercise on menstrual regularity and quality of life in pco women

NCT ID: NCT04744896 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Effects Of Combined Cryolipolysis And High Intensity Interval Training On Insulin Resistance And Body Composition In Polycystic Ovarian Patients

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

this study will be carried to investigate the effect of cryolipolysis and high intensity interval training on insulin resistance and body composition in pco women

NCT ID: NCT04723862 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

CBS010
Start date: November 12, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to determine if, in mid- to late pubertal girls with hyperandrogenism (HA), androgen-receptor blockade (spironolactone) alone normalizes sleep-wake luteinizing hormone (LH) pulse frequency (primary endpoint) and overall LH and follicle-stimulating hormone secretion (secondary endpoints).

NCT ID: NCT04670393 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Antioxidant Supplement Associated With Oral Probiotics in Patients With PCOS in IVF

Start date: December 2, 2020
Phase: N/A
Study type: Interventional

The aim of the study is to study the effect of an antioxidant food supplement associated with probiotics on the oocyte quality response, oxidative stress and microbiota function in an in vitro fertilization cycle in patients with polycystic ovarian syndrome

NCT ID: NCT04650880 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome

Start date: January 26, 2021
Phase: N/A
Study type: Interventional

This is a randomized double-blind controlled trial on the effect of vitamin D supplementation to assess the ovulation rate of women with polycystic ovary syndrome (PCOS) and other reproductive, endocrine and metabolic outcomes after one year of treatment.

NCT ID: NCT04597099 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion

CRM010
Start date: October 26, 2022
Phase: Early Phase 1
Study type: Interventional

This study is trying to find out if flutamide (a medication that blocks the effects of testosterone) may help normalize an aspect of pituitary function (specifically, gonadotropin surge generation) in PCOS. This is a randomized, placebo-controlled, double-blinded, crossover study. The investigators hypothesize that in estradiol-pretreated women with PCOS, acute progesterone augmentation of FSH release (positive feedback) will be enhanced by flutamide.

NCT ID: NCT04528849 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Comparison of Ovulation Induction Cycle Outcomes Between Early and Late Dose Increments for Low Dose Gonadotropin Step-up Protocol Among Infertile Women Diagnosed With Polycystic Ovary Syndrome: Prospective Randomised Trial

Start date: August 20, 2020
Phase: N/A
Study type: Interventional

Low dose gonadotropin step-up ovulation induction treatment is the universally accepted and utilized teratment protocol for infertile women diagnosed with polycystic ovary syndrome (PCOS). First dose increment is advised on 14th day of ovarian stimulation with gonadotropins to decrease multiple follicle generation and cycle cancellation rates. However, clinicians impatiently increase gonadotropin dose on 7th day of stimulation without strong scientific evidence. This randomised controlled study will be the first study which will compare safety and ovulation induction cyle outcomes of early and late dose increments among infertile women diagnosed with PCOS.

NCT ID: NCT04453306 Recruiting - Obesity Clinical Trials

Treatment of Obesity With Topiramate in Patients With Polycystic Ovary Syndrome

Start date: May 2014
Phase: Phase 4
Study type: Interventional

Treatment of obesity related to Polycystic Ovary Syndrome with topiramate or placebo to assess improvement of clinical and laboratory parameters after 6 months of follow-up

NCT ID: NCT04407754 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Myo-Inositol for Infertility in PCOS

Start date: December 19, 2020
Phase: N/A
Study type: Interventional

This will be a prospective, double-blind randomized clinical trial of letrozole and placebo versus letrozole and inositols for up to 5 treatment cycles of ovulation induction or until pregnancy is achieved. All participants and members of the research team will be blinded to the treatment arms. Placebo and inositol supplement will be packaged to appear the same, tested, and packaged by a commercial supply company. The inositols will be a 40:1 blend of myo-inositol and D-chiro inositol.

NCT ID: NCT04268563 Recruiting - Infertility Clinical Trials

Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients

Start date: January 10, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Investigators will evaluate and compare the efficacy of Sitagliptin/Metformin to metformin and sitagliptin on gdf9 and bmp15 gene expression on PCOS patients undergoing intracytoplasmic sperm injection(ICSI).