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Pneumothorax clinical trials

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NCT ID: NCT06088901 Recruiting - Clinical trials for Primary Spontaneous Pneumothorax

Autologous Blood Patch for Primary Spontaneous Pneumothorax

Start date: June 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to show that treatment with prophylactic autologous blood patch (ABP) after management of primary spontaneous pneumothorax (PSP) is feasible, reduces the incidence of prolonged air leaks, and reduces hospital length of stay. An ABP is a medical procedure that uses one's own blood in order to close one or many holes identified in the lungs. The blood modulates the pressure of the lungs and forms a clot, sealing the leak. Primary spontaneous pneumothorax is an abnormal collection of air in the pleural space between the lung and the chest wall.

NCT ID: NCT06075836 Active, not recruiting - Pleural Effusion Clinical Trials

AI Assisted Detection of Chest X-Rays

AID-CXR
Start date: October 31, 2023
Phase:
Study type: Observational

This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838). The Lunit INSIGHT CXR is a validation study that aims to assess the utility of an Artificial Intelligence-based (AI) chest X-ray (CXR) interpretation tool in assisting the diagnostic accuracy, speed, and confidence of a varied group of healthcare professionals. The study will be conducted using 500 retrospectively collected inpatient and emergency department CXRs from two United Kingdom (UK) hospital trusts. Two fellowship trained thoracic radiologists will independently review all studies to establish the ground truth reference standard. The Lunit INSIGHT CXR tool will be used to analyze each CXR, and its performance will be measured against the expert readers. The study will evaluate the utility of the algorithm in improving reader accuracy and confidence as measured by sensitivity, specificity, positive predictive value, and negative predictive value. The study will measure the performance of the algorithm against ten abnormal findings, including pulmonary nodules/mass, consolidation, pneumothorax, atelectasis, calcification, cardiomegaly, fibrosis, mediastinal widening, pleural effusion, and pneumoperitoneum. The study will involve readers from various clinical professional groups with and without the assistance of Lunit INSIGHT CXR. The study will provide evidence on the impact of AI algorithms in assisting healthcare professionals such as emergency medicine and general medicine physicians who regularly review images in their daily practice.

NCT ID: NCT06053476 Recruiting - Pain, Postoperative Clinical Trials

Optimal Postoperative Chest Tube and Pain Management in Patients Surgically Treated for Primary Spontaneous Pneumothorax (Pneumotrial)

Start date: November 8, 2023
Phase: N/A
Study type: Interventional

Guidelines lack high quality evidence on optimal postoperative chest tube and pain management after surgery for primary spontaneous pneumothorax (PSP). This results in great variability in postoperative care and length of hospital stay (LOS). Chest tube and pain management are prominent factors regarding enhanced recovery after thoracic surgery, and in standardised care they are crucial to improve quality of recovery and decrease LOS. Historically, postoperative chest tubes are left in place for at least a fixed number of 3-5 days, irrespective of absence of air leakage. This period was deemed necessary for adequate pleurodesis and prevention of recurrence. However, it is suggested that removal on the same day of surgery is safe and associated with a reduced LOS. Regarding postoperative pain management, thoracic epidural analgesia (TEA) is the gold standard for postoperative pain management following video-assisted thoracic surgery (VATS). Although the analgesic effect of TEA is clear, it is associated with hypotension and urinary retention. Therefore, unilateral regional techniques, such as paravertebral blockade (PVB), are developed. The investigators hypothesize that early chest tube removal accompanied by a single-shot paravertebral blockade (PVB) for analgesia is safe regarding pneumothorax recurrence and non-inferior regarding pain, but superior regarding LOS when compared to standard conservative treatment.

NCT ID: NCT06022081 Recruiting - Pneumothorax Clinical Trials

Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax

LUSvsCXR
Start date: September 27, 2023
Phase: N/A
Study type: Interventional

Sunnybrook Health Sciences Center annually provides assistance to approximately 600 cardiac surgeries and 1500 trauma patients, many of whom require chest tubes to prevent blood and fluids from accumulating in the pleural cavities surrounding the heart. During the removal of chest tubes, there is a risk of air leaking into these cavities, leading to pneumothorax, a critical condition occurring in approximately 5-26% of cases, associated with increased complications and mortality. Currently, the diagnosis of pneumothorax is primarily based on chest X-rays (CXR), despite their limitations and low reliability. As an alternative method, lung ultrasound (LUS) offers several advantages: it is safer, less expensive, and less painful for patients compared to CXR. However, there is a lack of comparative data on the accuracy and interrater reliability of these two diagnostic approaches after chest tube removal. This study aims to evaluate the accuracy of lung ultrasound performed by medical trainees in diagnosing pneumothorax in cardiac and trauma patients. By comparing LUS to CXR, the investigators seek to determine if LUS provides a more reliable and precise diagnosis. This study has the potential to enhance patient care by establishing a more effective and accessible method for diagnosing pneumothorax post-chest tube removal.

NCT ID: NCT05971511 Enrolling by invitation - Pneumothorax Clinical Trials

Current Practice for Management of Pneumothorax in Egypt

Start date: July 27, 2023
Phase:
Study type: Observational

There are standard well-known guidelines for pneumothorax management with minimal difference between societies and associations. We are investigating how much of these guidelines are actually being followed in different healthcare facilites in Egypt. This is a questionnaire that will be sent to all healthcare givers in Egypt acorss different cities and facilities with multiple choice questions presenting different case scenarios and the management options being given to the patient.

NCT ID: NCT05963945 Completed - Pleural Effusion Clinical Trials

Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical Practice

Start date: October 18, 2022
Phase:
Study type: Observational

The primary objective is to evaluate the performance parameters of the proposed DLAD (Carebot AI CXR) in comparison to individual radiologists.

NCT ID: NCT05910112 Recruiting - Pleural Effusion Clinical Trials

Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention

PROSPECT
Start date: September 1, 2020
Phase:
Study type: Observational

The PROSPECT study aims to look at the number of problems or side effects which occur after patients have had a procedure completed to remove fluid or air from the space between the lung and the chest wall. Other information will also be collected to see whether anything else affects which patients have problems after the procedure such as bleeding or infection. This study will also investigate whether it is possible to find out which patients are likely to feel a lot better after the procedure. Not all patients feel significantly better but it is not clear why this is. There are a number of different reasons patients may not feel better, for example if the lung is not able to fully re-expand. The study aims to look at whether it is possible to predict these problems before the procedure using ultrasound. If it is possible to find the answers to some of these questions it might be possible to prevent patients undergoing treatments which are not likely to benefit them. The study will use information already collected as part of clinical care, as well as questionnaires from patients receiving care at a variety of centres. The different features of these centres will also be considered in analysis.

NCT ID: NCT05904574 Completed - Lung Cancer Clinical Trials

Effectiveness of the Autologous Blood Patch Method in Lung Biopsies

Start date: October 20, 2020
Phase:
Study type: Observational

In this retrospective study, investigators aimed to evaluate the effectiveness of the autologous blood patch method in percutaneous transthoracic lung biopsies performed with the coaxial technique.

NCT ID: NCT05903209 Enrolling by invitation - Pneumothorax Clinical Trials

A Study to Evaluate Chang Gung Pneumothorax Detection Software

Start date: June 13, 2022
Phase:
Study type: Observational

The Chang Gung Pneumothorax Detection Software is a medical software that can automatically detect whether there is a pneumothorax in Chest X-Ray. The purpose of this study is to verify whether the Chang Gung Pneumothorax Detection Software can correctly identify patients with pneumothorax in Chest X-Ray. The results of the software analysis will be used for the performance of the software on the primary and secondary outcomes.

NCT ID: NCT05861037 Completed - Child, Only Clinical Trials

Thoracoscopy for Idiopathic Pneumothorax in Children

PNOPED
Start date: November 1, 2022
Phase:
Study type: Observational

The goal of this retrospective study is to describe the outcomes of spontaneous idiopathic pneumothorax treated by thoracoscopy with pleural abrasion and blebectomy. The main questions it aims to answer are: - are there risk factors leading to pneumothorax recurrence? - are pleural abrasion and blebectomy really diminishing the recurrence of pneumothorax?