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Peripheral Neuropathy clinical trials

View clinical trials related to Peripheral Neuropathy.

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NCT ID: NCT00826345 Completed - HIV Infections Clinical Trials

Acupuncture/Moxibustion (Acu/Moxa) for Distal Symmetric Peripheral Neuropathy (DSP) in HIV

TCMAcuPilot
Start date: January 2009
Phase: N/A
Study type: Interventional

This preliminary study will investigate the use of Acupuncture and Moxibustion (Acu/Moxa) for distal symmetric peripheral neuropathy (DSP) associated with HIV applying traditional Chinese medicine (TCM) evaluations conducted by a diagnostic acupuncturist. The investigators will evaluate the role of Acu/Moxa in reducing the symptoms of DSP related to HIV/AIDS and treatment side effects. The effects of symptom reduction on quality of life will also be examined. This application will establish a proof of principle for the role of Acu/Moxa in the treatment of DSP and provide data that will serve as a foundation for establishing a future larger clinical trial.

NCT ID: NCT00822198 Completed - Clinical trials for Peripheral Neuropathy

The Effect of Plantar Vibration on the Progression of Peripheral Neuropathy

Start date: March 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effect of vibration of the plantar surface of the foot on peripheral neuropathy.

NCT ID: NCT00763087 Completed - Diabetes Mellitus Clinical Trials

Effect of Weight-Bearing Exercise on People With Diabetes and Neuropathic Feet

Start date: September 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if people with Diabetes Mellitus and peripheral neuropathy can increase their activity (i.e. walking or stationary biking) and leg strength without having an increase in foot problems compared to a group of people with diabetes and peripheral neuropathy that do no exercise. Our hypothesis is that the weight-bearing exercise group will achieve greater increases in weight-bearing activity (i.e., increased steps/day and cumulative load) and leg strength compared to the non-weight bearing exercise group and the non-exercising control group; and there will be no clinically meaningful difference in incidence or indicators of foot lesions between groups.

NCT ID: NCT00713817 Completed - Pain Clinical Trials

A Study to Determine the Maintenance of Effect After Long-term Treatment of Sativex® in Subjects With Neuropathic Pain

Start date: March 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the maintenance of effect after long-term treatment of Sativex® in subjects with neuropathic pain.

NCT ID: NCT00713323 Completed - Pain Clinical Trials

A Study to Compare the Safety and Tolerability of Sativex® in Patients With Neuropathic Pain.

Start date: October 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of long term therapy with Sativex® in relieving neuropathic pain.

NCT ID: NCT00711880 Completed - Pain Clinical Trials

A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.

Start date: May 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of Sativex® compared with placebo in relieving peripheral neuropathic pain associated with allodynia.

NCT ID: NCT00710554 Completed - Pain Clinical Trials

A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia

Start date: August 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of Sativex® compared with placebo in relieving peripheral neuropathic pain associated with allodynia.

NCT ID: NCT00603265 Completed - Neuropathic Pain Clinical Trials

Safety and Efficacy Study of ADL5859 in Participants With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

Start date: November 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of ADL5859 in relieving the pain associated with diabetic peripheral neuropathy (DPN) compared with placebo and duloxetine (a marketed drug approved for the treatment of painful DPN). The pain symptoms of DPN are thought to be due to damage to nerves caused by the diabetes.

NCT ID: NCT00489411 Completed - Pain Clinical Trials

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Start date: April 2008
Phase: Phase 3
Study type: Interventional

RATIONALE: Duloxetine may lessen peripheral neuropathy caused by chemotherapy. It is not yet known whether duloxetine is more effective than a placebo in treating peripheral neuropathy caused by chemotherapy. PURPOSE: This randomized phase III trial is studying duloxetine to see how well it works compared with a placebo in treating peripheral neuropathy caused by chemotherapy in patients with cancer.

NCT ID: NCT00471445 Completed - Pain Clinical Trials

Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients

Start date: October 2007
Phase: Phase 3
Study type: Interventional

RATIONALE: Topical cream containing amitriptyline and ketamine may help relieve pain, numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether topical amitriptyline and ketamine cream is more effective than a placebo in treating peripheral neuropathy caused by chemotherapy. PURPOSE: This randomized phase III trial is studying the side effects and how well topical amitriptyline and ketamine cream work compared with a placebo in treating peripheral neuropathy caused by chemotherapy in patients with cancer.