Clinical Trials Logo

Peri-implantitis clinical trials

View clinical trials related to Peri-implantitis.

Filter by:

NCT ID: NCT03501537 Completed - Peri-Implantitis Clinical Trials

Association of Keratinised Mucosa Around Implants and Teeth With Peri-implant/Periodontal Disease and Soft Tissue Conditioning

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Lack of keratinised mucosa around dental implants and teeth is associated with plaque accumulation and worse tissue conditions. However, there is lack of data on the influence of the presence/lack of keratinised mucosa on the periodontal condition. Hence, soft tissue conditioning by grafting with a gingival graft is aimed at improving the quality of the peri-implant conditions

NCT ID: NCT03497065 Completed - Peri-Implantitis Clinical Trials

Dental Implant Care and Oral Hygiene Practices

Start date: April 1, 2017
Phase:
Study type: Observational

Objective: This study investigated how patients' knowledge, attitude, and perceptions influence their oral hygiene practices as well as peri-implant health. Materials and Methods: Participants with single implant crowns placed in 2007-2011 completed a questionnaire that examined their knowledge, attitude, and perceptions on oral hygiene practices and peri-implant health before receiving a periodontal examination, prophylaxis, and oral hygiene education. Clinical parameters recorded were peri-implant probing depths and plaque index, width of keratinized mucosa, implant crown characteristics, reason for tooth loss, and diagnosis of peri-implant health.

NCT ID: NCT03421717 Completed - Clinical trials for Peri-implant Mucositis

The Effect of Peri-implant Surgery and Chair-side Supportive Post Surgical Peri-implant Therapy

Start date: November 1, 2012
Phase: N/A
Study type: Interventional

Peri-implantitis is defined as inflammation in the mucosa surrounding an oral implant with loss of supporting bone. The goals of peri-implantitis treatment are to resolve inflammation and to arrest the progression of disease. It is important to systematically gather information on the effect of surgical peri-implant treatment and to assess different protocols regarding chair-side maintenance of peri-implant tissue after surgery The aims of this clinical investigation are to evaluate the clinical, microbiological and radiographic outcomes of surgical treatment of peri-implantitis and to evaluate the efficacy of 2 supportive treatment protocols based on the use of titanium cyrettes or by the use of a flexible, biodegradable chitosan brush. Furthermore, to evaluate the impact of this therapy on selected biochemical markers associated with chronic inflammation and bone tissue destruction.

NCT ID: NCT03407911 Completed - Clinical trials for Periodontal Diseases

Microbiota Around Periodontal Teeth and Implants Affected by Peri-implant Disease.

Start date: February 1, 2018
Phase:
Study type: Observational [Patient Registry]

The purpose of the study was to evaluate, from a microbiological point of view, microbiota around teeth and implants in the same patient affected by periodontal disease and peri-implant disease, all compared with a healthy tooth. From the identification of particular bacterial species in the examined sites, it is intended to be traced back to the identification of a clear etiopathogenic process, which may shed light on the similarities and differences between the two diseases. In recognition of these mechanisms, the investigators think to develop new therapeutic strategies for the future.

NCT ID: NCT03384446 Completed - Peri-Implantitis Clinical Trials

Dental Hygiene and Peri-Implant Tissues Homeostasis

Start date: November 22, 2017
Phase: N/A
Study type: Interventional

Dental implants have revolutionized the field of dentistry, providing improvements in function and esthetics. They are not, however, without risks. Bone loss around implants (i.e. periimplantitis) is an emerging public health concern. Untreated, peri-implantitis leads to implant loss and jawbone defects. Nonetheless, existing therapies have failed to show long-term efficacy. The pathogenesis of peri-implantitis is believed to be of bacterial etiology similar to periodontal disease. Therefore, existing treatments duplicate strategies for the treatment of natural teeth. However, the titanium (Ti) surface of implants is quite dissimilar to teeth. Recent work from our lab has demonstrated that peri-implantitis is associated with increased release of Ti particles around implants. These findings suggest that treatments targeting periimplantitis must be designed around Ti material properties. A gap in knowledge exists regarding the potential triggers of increased Ti dissolution from the implant surface and the mechanisms by which Ti dissolution products amplify peri-implant inflammation. The aim of this study is to determine if the use of tooth-driven treatment approaches increase Ti in the submucosal plaque.

NCT ID: NCT03383120 Completed - Peri-Implantitis Clinical Trials

Diode Laser for Treatment of Peri-implantitis

LAS
Start date: October 10, 2017
Phase: N/A
Study type: Interventional

The primary objective is to evaluate the clinical and patient-centered outcomes of non-surgical mechanical debridement with adjunctive repeated diode laser application (test) in comparison with conventional surgical treatment and adjunctive systemic antibiotics (control), for treatment of peri-implantitis lesions, following an observation period of one year.

NCT ID: NCT03373448 Completed - Peri-Implantitis Clinical Trials

Treatment of Mild to Moderate Peri-implantitis Using an Oscillating Chitosan Device

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

34 patients diagnosed with mild to moderate peri-implantitis, defined as 2-4 mm peri-implant bone loss, will be randomized to either test treatment with Labrida BioClean® or control treatment with titanium curettes. In total 40 subjects (20 % drop-out rate), treated by 5 clinicians at 5 centers will be included in the study.

NCT ID: NCT03345329 Completed - Clinical trials for Periodontal Diseases

Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms

Start date: October 1, 2015
Phase: N/A
Study type: Observational

More than ninety percent of adults in Taiwan are suspected to carry periodontal disease, which causes bad breath, swollen and bleeding gums, plaque and even tooth loss. Half of the patients, however, are ignorance these clinical syndromes because of no obvious pain. In this study, the investigators selected six periodontal disease-associated bacteria strains, including Porphyromonas gingivalis (Pg), Fusobacterium nucleatum (Fn), Actinobacillus actinomycetemcomitans (Aa), Tannerella forsythia (Tf), Treponema denticola (Td) and Prevotella intermedia (Pi) as diagnostic markers. Using real-time PCR and MALDI Biotyper, the investigators will establish the database of oral microorganisms in Taiwanese people, providing periodontal disease clinical markers of high-risk groups and the basis for personal medicine of therapy in the future.

NCT ID: NCT03312582 Completed - Peri-Implantitis Clinical Trials

Locally Delivered 1% Metformin Gel in Peri-implantitis

Start date: March 15, 2015
Phase: Phase 4
Study type: Interventional

This study evaluates the efficacy of 1% local metformin gel in deep periimplant pockets of type 2 diabetes mellitus patients. Half of the participants will receive 1% metformin gel with manual debridement while the other half will receive a placebo with manual debridement.

NCT ID: NCT03241953 Completed - Clinical trials for Periodontal Diseases

COMPARISION OF DIFFERENT TREATMENT METHODS OF PERI-IMPLANTITIS

Start date: April 23, 2014
Phase: N/A
Study type: Interventional

In this randomized, controlled study, 18 patients with peri-implantitis were included. A total of forty dental implants were debrided with either ultrasonic instruments (test, n=20) or plastic scaler (control, n=20). Gingival recession depth (RD), keratinized tissue width (KTW), probing depth (PD), Gingival Index (GI) were evaluated at baseline and after 6 months. CBCT radiographs were used to evaluate peri-implant bone loss. Supportive and nonsurgical periodontal therapies were firstly consulted to reduce the inflammation, occurring due to the surgical treatments of the defects. The formation of bacterial biofilm on implant surfaces was removed by ultrasonic scaler and air polishing using abrasive powders or conventional plastic scaler with klorhegsidin combination.