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Peri-implantitis clinical trials

View clinical trials related to Peri-implantitis.

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NCT ID: NCT03191721 Completed - Clinical trials for Periodontal Diseases

Triclosan Toothpaste in the Maintenance Phase of Peri-implantitis Treatment.

Start date: June 2010
Phase: Phase 3
Study type: Interventional

The aim of this study was to evaluate the effects of a dentifrice containing 0.3% triclosan on periodontal and peri-implant parameters in patients, with or without periodontitis, treated for peri-implantitis and that were enrolled in a maintenance phase for two years.

NCT ID: NCT03163602 Completed - Peri-Implantitis Clinical Trials

Surgical Treatment of Peri-implantitis

STP
Start date: May 15, 2017
Phase: N/A
Study type: Interventional

The aim of this randomized controlled study is to evaluate the outcome of surgical treatment of peri-implantitis with and without the use of a bone substitute graft covered by a collagen membrane. There will be a follow up period of 12 months. Outcome measures will include assessments of inflammation, probing depth, recession, radiological parameters and PROMs.

NCT ID: NCT03157193 Completed - Peri-Implantitis Clinical Trials

Effect of Hyaluronic Acid on Perimplantitis

Start date: September 2014
Phase: Phase 4
Study type: Interventional

The effect of the hyaluronic acid treatment on peri-implantitis has not been tested. The aim was to analyze the effect of a hyaluronic acid-containing gel on the clinical variables and the expression of biochemical inflammatory markers in the crevicular fluid of implants receiving perimplantitis treatment.

NCT ID: NCT03145610 Completed - Clinical trials for Biological Markers; Dental Implants; Cytokines; Triclosan; Toothpastes; Peri-Implantitis; Microbiology

Impact of a Triclosan-containing Toothpaste During the Progression of Experimental Peri-implant Mucositis

Start date: June 1, 2013
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the influence of a triclosan-containing toothpaste in the profile of osteo-immunoinflammatory mediators in the peri-implant crevicular fluid (PICF) and in the clinical parameters during the progression of experimental peri-implant mucositis.

NCT ID: NCT03142828 Completed - Periimplantitis Clinical Trials

Implant Healing Abutment and Chlorhexidine

CHX-HA
Start date: April 15, 2017
Phase: Phase 4
Study type: Interventional

The work hyposesis is based on the application of a chlorhexidine gel against the non-application on the healing abutments in patients who have received a submerged titanium implant to check its effect on healing and prevention of bacterial plaque accumulation during a period of 1 month.

NCT ID: NCT03127228 Completed - Peri-Implantitis Clinical Trials

Laser-Assisted Regenerative Surgical Therapy for Peri-implantitis

Start date: June 26, 2017
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate if using Erbium-doped yttrium aluminium garnet laser, Erbium YAG laser (Er:YAG) laser could have adjunctive benefits to the conventional standard mechanical debridement to ablate the infected tissue around the dental implant and detoxify the contaminated implant surface for resolving peri-implant infection and enhance bone regeneration of peri-implant defects.

NCT ID: NCT03100435 Completed - Peri-Implantitis Clinical Trials

Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study

Start date: April 20, 2017
Phase: N/A
Study type: Interventional

The American Association of Oral and Maxillofacial Surgeons estimated that 69% of adults ages 35 to 44 have lost at least one permanent tooth. Dental implants have revolutionized dentistry by providing tooth-like replacement for missing teeth and a solution that is predictable with long-term success.. After the implant is placed, natural bacteria from the mouth can develop around implants just like around natural teeth. Studies have shown that bacterial contamination can cause peri-implantitis- gum disease or inflammation around the implant, eventually leading to bone loss. Removing bacteria from dental implant surfaces can prevent peri-implantitis, and surface debridement constitutes the basis of treatment of peri-implant disease. Typically, mechanical hand instrumentation using curettes to remove biofilm and calculus is the main basis for periodontal therapy. However, total debridement is difficult, and the hand tools may damage the surface of the implant and making it more plaque retentive. Studies have shown that mechanical non-surgical therapy alone is not sufficient to treat peri-implantitis. There is evidence that a dental laser may be an effective method to remove bacteria from implant surfaces, with less damage to the surface. One type of dental laser, Er:YAG, appears optimal for implant decontamination as the Er:YAG laser energy is primarily absorbed by water, resulting in vaporization of bacteria and minimal surface alterations on the implant surface.The aim of this study is to evaluate the efficiency of biofilm decontamination of Er:YAG laser compared to carbon fiber curette.

NCT ID: NCT03047291 Completed - Peri-implantitis Clinical Trials

Effect of Probiotic Lactobacillus Reuteri in the Treatment of Mucositis and Periimplantitis

Start date: January 1, 2014
Phase: Phase 4
Study type: Interventional

Evaluate clinically and microbiologically the effect of the oral probiotic Lactobacillus reuteri Prodentis (PerioBalance®, Sunstar, Switzerland) on implants with mucositis or periimplantitis, as a coadjuvant treatment of mechanical therapy.

NCT ID: NCT03031392 Completed - Peri-Implantitis Clinical Trials

Sensitivity and Specificity of Peri-Implantitis-Related Parameters

Start date: July 1, 2016
Phase: N/A
Study type: Observational

Bleeding on probing demonstrated to have high specificity with certain level of sensitivity to detect periodontal disease. Again, understanding the weak hemidesmosome attachment to the implant surface is imperative to discern on the probe penetration extent and subsequent bleeding. In the presence of inflammation, bleeding should be present indicating high sensitivity when probing deeper sites; nevertheless the lack thereof in healthy condition does not seem to translate high specificity. In this sense, it is noteworthy to mention that the mucogingival shift after implant placement often decreases the presence of keratinized mucosa, triggering a greater inflammatory condition on the peri-implant tissues. Thereupon, bleeding on probing, although might reliably indicate presence of disease, it does not seem to be a suitable diagnostic parameter. On the other side, suppuration characterizes the necrosis of peri-implant tissues, being rich in polymorphonuclear cells and as such, a sensitive indicator of bone turnover. In this sense, it must be noted that, if detected in early stages where bone resorption has not occurred yet, it might be a consequence of a foreign body reaction (i.e., residual cement or floss). Therefore, in the diagnosis of peri-implantitis, radiographic examination must be always incorporated to the clinical assessment as the 'gold standard'. Hence, the aim of this case-control study was to assess the diagnostic accuracy of peri-implantitis-related clinical parameters compared to otherwise healthy dental implants.

NCT ID: NCT03018795 Completed - Peri-Implantitis Clinical Trials

Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis

Start date: September 2014
Phase: N/A
Study type: Interventional

Decontamination procedure is a challenging factor that affects the success of surgical regenerative therapy (SRT) of peri-implantitis. The purpose of the present study was to determine the impact of additional ozone therapy for the decontamination of implant surfaces in SRT of peri-implantitis. A total of 21 patients with moderate or advanced peri-implantitis were randomly allocated to the test group (ozone group) with the use of sterile saline with additional ozone therapy or the control group with sterile saline alone for decontamination of the implant surfaces in SRT of peri-implantitis. Clinical and radiographic outcomes were evaluated at baseline and 6 months postoperatively