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Clinical Trial Summary

Scalp to cortex distance (SCD), as a key technological parameter of brain stimulation, has been highlighted in the guidelines of non-invasive brain stimulation. However, in the context of age-related brain changes, the region-specific SCD and its impact on stimulation-induced electric field in different types of neurodegenerative diseases remain unclear.


Clinical Trial Description

Objective: This study aimed to investigate the region-specific SCD and its relationship with morphometric features and cognitive function in age- and disease-specific populations. Methods: The SCD and cortical thickness (CT) of left primary motor cortex (M1) and dorsolateral prefrontal cortex (DLPFC) were measured in cognitively normal adults and dementia patients. CT-adjusted SCD was used to control the influence of CT on SCD. Head model was developed to simulate the impact of SCD on the electric field induced by transcranial electrical stimulation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05967390
Study type Observational
Source Chinese University of Hong Kong
Contact Hanna LU, PhD
Phone 28314305
Email hannalu@cuhk.edu.hk
Status Recruiting
Phase
Start date June 15, 2023
Completion date June 14, 2025

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