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Pain clinical trials

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NCT ID: NCT05441995 Not yet recruiting - Pain Clinical Trials

Cryotherapy Efficacy During Pulp Therapy of the Mandibular First Permanent Molars in Children

Start date: June 2022
Phase: N/A
Study type: Interventional

The aim of the study is to assess the efficacy of cryotherapy application on the success of inferior alveolar nerve block (IANB) in reducing pain during pulp therapy of the mandibular first permanent molars with irreversible pulpitis (IP) in children age from 7 to 16 years. The null hypothesis (H0) supposed no difference in pain intensity during pulp therapy of primary molars with IP anesthetized with IANB with and without cryotherapy application. The secondary aim was to evaluate the children's behavior before and after pulpectomy in the two groups.

NCT ID: NCT05427877 Not yet recruiting - Pain Clinical Trials

Safety of Pulsing Heating Device Use on the Skin

Start date: June 2022
Phase: N/A
Study type: Interventional

We hope to assess the safety of a recurrent heating device for pain relief.

NCT ID: NCT05427266 Not yet recruiting - Pain Clinical Trials

Laparoscopic Transversus Abdominis Plane Block (LTAP) for Appendicectomy Versus Standard Port Site Treatment

TapBlock
Start date: July 2022
Phase: N/A
Study type: Interventional

This study aims to compare Laparoscopic assisted LTAP (Transversus Abdominis Plane) to standard port-site infiltration in terms of post-operative visual analogue scores (VAS) for pain at 3, 6, 12 and 24 hours following laparoscopic appendicectomy Tap Block is a standard conventional analgesia protocol for laparoscopic appendicitis used in Beaumont Hospital, and other hospitals throughout Ireland. The medicinal product for both groups is the same - Bupivacaine. The mode of administration is what this study is reviewing: Control group (Standard port site infiltration) and Study Group - Laparoscopic Transversus Abdominis Plane Block

NCT ID: NCT05411913 Not yet recruiting - Pain Clinical Trials

Topical CBD for Musculoskeletal Pain

Start date: July 1, 2022
Phase: Phase 3
Study type: Interventional

Various OTC and CBD containing topicals are evaluated in a double blind survey. Each sample has a QR code that is to be scanned before applying. The QR code links to a survey form with application instructions and collects participant information and feedback.

NCT ID: NCT05388994 Not yet recruiting - Pain Clinical Trials

Exercise-related Irisin on Inflammation and Pain

Start date: May 18, 2022
Phase: N/A
Study type: Interventional

Osteoarthritis (OA) is a chronic disease that usually starts with cartilage damage in weight-bearing joints and then causes pain and loss of function secondary to damage in surrounding tissues. Osteoarthritis, which is seen with a frequency of approximately 10% in men over the age of 60 and approximately 18% in women, ranks first among the diseases related to the joint. Many factors such as age, gender, obesity, physical activity, trauma, and genetic factors are involved in the etiology of the disease. In osteoarthritis, intra-articular production and destruction events can occur simultaneously, so it is a dynamic process. Among the joints in the lower and upper extremities, osteoarthritis is most common in the knee joint. Various approaches are used in the treatment, including drug therapy, hyaluronic acid injection, use of glucosamine and chondritis sulfate, exercises, physiotherapy applications, and diet applications for weight loss to reduce pain and increase physical function. Physiotherapy and rehabilitation are important treatment options in OA. Generally, range of motion exercises, strengthening exercises, and endurance exercises are applied to patients. An exercise program can be as effective as an NSAID in reducing pain. Decreased quadriceps muscle strength is a finding seen in patients with symptomatic knee OA. In addition, aerobic exercise has the potential to improve cardiovascular fitness, many of the comorbidities often associated with OA, such as diabetes, hypertension, and obesity. Because OA is a major public health problem, a less costly population-based approach is desirable. Therefore, the aim of this study was to investigate the effects of exercise-related irisin on inflammation and pain in patients with OA who underwent exercise.

NCT ID: NCT05369923 Not yet recruiting - Pain Clinical Trials

Survey of Knowledge and Attitude of Pain in Anesthesia Residents of Thailand

Start date: October 1, 2022
Phase:
Study type: Observational

This study is a prospective descriptive cross-sectional survey using the modified Knowledge and Attitudes Survey Regarding Pain (KASRP) in English via an online google form.

NCT ID: NCT05338983 Not yet recruiting - Pain Clinical Trials

Effect of Different Approaches of Delivering Local Dental Anesthesia on Pain Perception in Children.

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to compare the efficacy of three different approaches of local anesthesia (LA) administration (Warm[37°C] LA, Buffered LA, and BUZZY device) on pain perception to young children ( 6-12 years old) using sound -eye -motor and Wong-Baker FPR scales.

NCT ID: NCT05313789 Not yet recruiting - Pain Clinical Trials

Analgesia Nociception Index for Pain Monitoring in Intensive Care Units

Start date: April 11, 2022
Phase:
Study type: Observational

The aim of this study is to examine the usability of ANI in patients who will be treated in intensive care unit.

NCT ID: NCT05244772 Not yet recruiting - Pain Clinical Trials

Quality of Recovery After Day Care Surgery With App Controlled Remote Monitoring: a Randomized Controlled Trial

QuReMo
Start date: March 2022
Phase: N/A
Study type: Interventional

Non blinded randomized controlled trial with mixed methods design. To assess the experienced quality of recovery after day care surgery between patients provided with remote home monitoring and patients receiving standard discharge care

NCT ID: NCT05220644 Not yet recruiting - Pain Clinical Trials

Management of Pain Respiratory Distress at the End of Life in Newborn Palliative Care in the Delivery Room

PALLI-ACC
Start date: February 2022
Phase:
Study type: Observational

The newborn feels pain and the newborn at the end of life, in the delivery room, is potentially exposed to pain and respiratory distress. Protocols for the management of end-of-life symptoms in the delivery room are used in current practice with very few validation studies. The protocol used in delivery rooms in Alsace uses fentanyl and midazolam intranasally. It has been used for 3 years and seems to provide satisfactory relief to newborn babies. In doing so, it seems to reassure parents about the quality of support and it seems to meet the expectations of professionals in these anxiety-provoking contexts. Scientific validation of these practices would allow wider dissemination to other maternity teams.