Effectiveness of Alveogyl and Cutanplast Dressing on Postoperative Pain Following Tooth Extraction: A Clinical Trial

Pain, Postoperative Clinical Trial

Official title:

Effectiveness of Alveogyl and Cutanplast Dressing on Postoperative Pain Following Tooth Extraction: A Clinical Trial

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT04779476
• Other study ID #: FRP/2021/319
• Status: Active, not recruiting
• Start date: March 4, 2021
• Est. completion date: December 2021

Study information

• Verified date: October 2021
• Source: Riyadh Elm University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study aims to assess the post-dental extraction pain following the application of two different dressing materials.

Alvogyl® and Absorbable gelatin sponges

Description:

Effective postoperative pain relief improves the quality of recovery and the resumption of normal activities. Many options are available for postoperative pain relief following tooth extraction including systemic analgesic, intra-alveolar socket dressing medicaments, and follow the postoperative instructions; the choice of the medication determined by drug availability, chance of side effect of some drugs and financial considerations. The use of intra-alveolar dressing materials is widely suggested in the literature such as Alvogyl® that used as palliative treatment which includes eugenol (analgesic, anti-inflammatory), iodoform (antimicrobial), and butamen (anesthetic). Absorbable gelatin sponges contain haemostatic material and may be used for local application in surgical procedures where traditional haemostasis is difficult. In addition to its haemostatic effect, an absorbable gelatin sponge can be used as a drug reservoir to provide sustained release of drugs

The aim of this study is to measure the pain intensity after using socket dressing materials following tooth extraction.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 50
• Est. completion date: December 2021
• Est. primary completion date: December 2021
• Gender: All
• Age group: 13 Years to 22 Years

Eligibility

Inclusion Criteria:

• Single tooth extraction

• Upper and lower teeth

Exclusion Criteria:

• Surgical extraction

• Medically compromised patients

• Presence of active infection

• Presence of pathology

Related Conditions & MeSH terms

• Facial Pain
• Pain, Orofacial
• Pain, Postoperative

Intervention

Other:
• Socket Dressing
Following dental extraction immediately, the socket will be dressed with one of the materials tested

Locations

Country	Name	City	State
Saudi Arabia	Ahmad Assari	Riyadh

Sponsors (1)

Lead Sponsor	Collaborator
Riyadh Elm University

Country where clinical trial is conducted

Saudi Arabia, 

References & Publications (4)

Bloomer CR. Alveolar osteitis prevention by immediate placement of medicated packing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000 Sep;90(3):282-4. — View Citation

Kafali H, Iltemur Duvan C, Gözdemir E, Simavli S, Oztürk Turhan N. Placement of bupivacaine-soaked Spongostan in episiotomy bed is effective treatment modality for episiotomy-associated pain. J Minim Invasive Gynecol. 2008 Nov-Dec;15(6):719-22. doi: 10.10 — View Citation

Kaur G, Athar M, Alam MS. Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis. Mol Carcinog. 2010 Mar;49(3):290-301. doi: 10.1002/mc.20601. — View Citation

Summers L, Matz LR. Extraction wound sockets. Histological changes and paste packs--a trial. Br Dent J. 1976 Dec 21;141(12):377-9. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	3 hrs post extraction pain	Visual analogue scale score for pain	three hours after the extraction
Primary	6 hrs post extraction pain	Visual analogue scale score for pain	six hours after the extraction
Primary	12 hrs post extraction pain	Visual analogue scale score for pain	twelve hours after the extraction
Primary	24 hrs post extraction pain	Visual analogue scale score for pain	twenty-four hours after the extraction