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Facial Pain clinical trials

View clinical trials related to Facial Pain.

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NCT ID: NCT06299995 Enrolling by invitation - Facial Pain Clinical Trials

Phenotype and Burden of a Midfacial Segment Pain

Start date: February 24, 2024
Phase:
Study type: Observational

The purpose of this study is to describe midfacial segment pain phenotype, burden and comorbidities in a multicentre and multidisciplinary setting. The ultimate goal is a comprehensive description of this type of pain allowing for its implementation in future classifications. This cross-sectional study is designed to describe midfacial segment pain in a clinical setting. Patients from rhinologic, headache and facial pain or oral medicine/dentistry secondary care centres will be recruited during a one year period. Individuals with other facial pain according to current classification such as sinonasal disorders, neoplasms, local infections, history of significant trauma associated with pain onset will be excluded. Data will be collected through a structured questionnaire covering pain characteristics, coexisting diagnoses, pain-related burden and consequences, physical examination and paranasal sinuses imaging.

NCT ID: NCT06298786 Not yet recruiting - Fatigue Clinical Trials

Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).

F-6MMT
Start date: April 2024
Phase:
Study type: Observational

Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain, and headaches. TMDs are classified according to the DC/TMD instrument in which the joint and pain axes are evaluated. However, there is no evaluation of mandibular function, and TMDs can result in a decrease in jaw strength and resistance. This leads to an increase in the chewing fatigue. Reliable and time-effective diagnostic methods for evaluating masticatory function are crucial in the clinical setting because of the high prevalence of TMD. Chewing efficiency is essential for food preparation and nutrient absorption, and muscle fatigue is a common problem affecting chewing ability. Despite this, there is a lack of validated tests to evaluate chewing fatigue in patients with TMD, which makes its consideration unnoticed in clinical practice. The modified six-minute functional chewing test (F-6MMT) was proposed as a tool to evaluate chewing ability and fatigue in patients with TMD. This test is an adaptation of a previously designed test in which subjects with mitochondrial pathology were evaluated; however, the subjects were not instructed to perform functional chewing during the test. In this version, modifications are added so that the test is as functional as possible, allowing chewing to be evaluated in a standardized way, and cut-off points established between healthy subjects and subjects with TMD in terms of chewing capacity in general and fatigue in particular. This study will follow standardized reporting guidelines and recruit participants from diverse clinical settings.

NCT ID: NCT06132594 Completed - Clinical trials for Temporomandibular Joint Disorders

Computed Guided Prolotherapy Versus Conventional Prolotherapy

Start date: October 2, 2021
Phase: N/A
Study type: Interventional

The aim of that study is to compare between conventional prolotherapy and computed guided prolotherapy in treatment of temporomandibular joint (TMJ) internal derangement.

NCT ID: NCT06127186 Recruiting - Clinical trials for Upper Respiratory Tract Infections

Phenotype of Headache and Facial Pain in Upper Respiratory Tract Infections

Start date: November 1, 2023
Phase:
Study type: Observational

The goal of this longitudinal study is to assess headache and facial pain features in patients with upper respiratory tract infections (URTI). The main question it aims to answer are: 1. What is the phenotype of headache / facial pain in URTIs 2. Does the above mentioned phenotype is associated with: 1. aetiologic factor (virus), 2. type of URTI 3. headache/facial pain experienced by patients in the past. Participants will: - answer standardized questions, - undergo physical examination, - have a swab test performend for antigens of common viruses causing URTI.

NCT ID: NCT06065969 Not yet recruiting - Clinical trials for Tension-Type Headache

Photobiomodulation Dosimetry s in Patients With Orofacial Pain

Start date: October 10, 2023
Phase: N/A
Study type: Interventional

This project aims to validate a dosimetry model for photobiomodulation treatment in patients with orofacial pain and tension-type headache symptoms. The study will involve 240 participants divided into four age groups. Different treatment approaches will be applied, including local photobiomodulation and systemic laser therapy. Various physiological measurements will be taken before, during, and after the treatments, including skin type, weight, height, blood pressure, and heart rate. Additionally, data from questionnaires on pain and headache symptoms will be analyzed. Monte Carlo simulation will be employed to validate the model based on these measurements and light transmission. The research addresses the need for effective pain management strategies in cases where medication-based treatments may have unwanted side effects.

NCT ID: NCT06051799 Recruiting - Clinical trials for Trigger Point Pain, Myofascial

Effects of Pressure Release of Myofascial Trigger Points on Mechanical Neck Pain.

Start date: September 25, 2023
Phase: N/A
Study type: Interventional

The study aims to compare the effectiveness of myofascial trigger point treatment using pressure release versus a control group in patients with mechanical neck pain, randomly assigned. In both groups a protocol of therapeutic exercise and postural correction will be carried out

NCT ID: NCT06021561 Recruiting - Multiple Sclerosis Clinical Trials

Orofacial Pain in Multiple Sclerosis

Start date: September 4, 2023
Phase:
Study type: Observational

Although the orofacial pain is not typical symptom of multiple sclerosis, more than 50% of the patients experience some kind of pain. Acute pain usually in form of trigeminal neuralgia, that occurred in 2-3% of patients with multiple sclerosis. Chronic pain occurred in 40-50% of patients and most common forms are headache. Aim of this study is to investigate prevalence and evaluate the form of orofacial pain in patients with multiple sclerosis treated in General hospital Varaždin in period from 01.01. 2017. to 31.12.2022. Results of this investigation will determine better understanding orofacial pain , treatment and impact on everyday life.

NCT ID: NCT05961501 Not yet recruiting - Headache Clinical Trials

The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin

Start date: July 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study is to evaluate the effectiveness of an aqueous solution containing CBD and CBN in the management of Facial Pain and Headache of Muscular Origin. A randomized (block randomization), double-blind, two-arm controlled trial will involve 42 adult patients diagnosed with Facial Pain and Headache of Muscular Origin which is lasting more than 3 months on the basis of clinical examination. Qualified study participants will be randomly assigned to two groups. The studied group will receive tan aqueous solution containing CBD and CBN, to drink at home in the dose determined by the attending physician, while the control group will receive an aqueous solution of placebo, to drink at home in the dose determined by the attending physician during this time. Each subject will be tested on the qualification day (D0), on 20 days after D0 (D20), and then 40 (D40) and 60 (D60) days after the qualification day using electromyography (EMG), pressure pain threshold test (PPT), clinical examination and surveys.

NCT ID: NCT05959174 Enrolling by invitation - Clinical trials for Myofacial Pain Syndromes

Evaluation of 3D Michigan Appliance

Start date: June 15, 2023
Phase: N/A
Study type: Interventional

- 20 patients will be divided into 2 groups - Group 1 : in which conventional appliance will be constructed after alginate impression - Group 2 : in which 3d printed appliance will be constructed after intra-oral scanning

NCT ID: NCT05877170 Recruiting - Oral-facial Pain Clinical Trials

Impact of Palmitoylethanolamide (PEA) in the Management of Oro-facial Pain

Start date: February 18, 2020
Phase: N/A
Study type: Interventional

Pain is the most common symptom faced by dentists, whether acute (pulpitis, acute periodontitis, post-surgical, etc.) or chronic (chronic periodontitis, muscle pain, TMJ disorders, BMS, OLP, etc.). The success of therapy depends on the reduction and management of pain. Therefore, over the past few years, the need has emerged, also in relation to the aging population, to analyze new molecules with pain-relieving activity and with low risk of inducing side effects and interactions with other drugs; capable of bringing about the reduction of oro-facial pain; and that lend themselves to prolonged use. Palmitoylethanolamide (PEA) is a bioactive lipid mediator similar to endocannabinoids (eCBs) that has been observed to have anti-inflammatory, analgesic, anticonvulsant, antimicrobial, antipyretic, antiepileptic, immunomodulatory, and neuroprotective activities. The objective is to clinically study, through a clinical trial, the pain-relieving and anti-inflammatory properties of a PEA-containing nutraceutical agent in the management of patients with orofacial pain, both neuropathic and nociceptive in nature.