Pain, Postoperative Clinical Trial
Official title:
Can we Predict Postoperative Analgesic Requirement by Intraoperative Nociception?
Verified date | May 2018 |
Source | Samsung Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
If the individual patient's pain is assessed and the amount of analgesic needed after surgery is predicted, appropriate injection of pain control and excessive injection of narcotic analgesic can be prevented. Therefore, investigators try to evaluate the degree of pain during surgery and the amount of analgesic use for management of postoperative pain.
Status | Completed |
Enrollment | 53 |
Est. completion date | October 19, 2018 |
Est. primary completion date | October 19, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years to 80 Years |
Eligibility |
Inclusion Criteria: undergoing liver resection (laparoscopic or laparotomy) Exclusion Criteria: patients who refused to participate patients who have cardiac arrythmia patients who have allergic history for remifentanil |
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | Samsung medical center | Seoul |
Lead Sponsor | Collaborator |
---|---|
Samsung Medical Center |
Korea, Republic of,
Dolin SJ, Cashman JN. Tolerability of acute postoperative pain management: nausea, vomiting, sedation, pruritus, and urinary retention. Evidence from published data. Br J Anaesth. 2005 Nov;95(5):584-91. Epub 2005 Sep 16. Review. — View Citation
Ledowski T, Burke J, Hruby J. Surgical pleth index: prediction of postoperative pain and influence of arousal. Br J Anaesth. 2016 Sep;117(3):371-4. doi: 10.1093/bja/aew226. — View Citation
Ledowski T, Sommerfield D, Slevin L, Conrad J, von Ungern-Sternberg BS. Surgical pleth index: prediction of postoperative pain in children? Br J Anaesth. 2017 Nov 1;119(5):979-983. doi: 10.1093/bja/aex300. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The correlation of requirement of postoperative analgesics for postoperative 24 hours and intraoperative nociception score | The consumption of patient controlled analgesia and intraoperative surgical pleth index score | intraoperative nociception score: 3 minutes during closure peritoneum and skin; requirement of postoperative analgesics: the first 24 hour in postoperative phase | |
Secondary | The correlation of requirement of postoperative analgesics for postoperative 6 hours and intraoperative nociception score | The consumption of patient controlled analgesia and intraoperative surgical pleth index score | intraoperative nociception score: 3 minutes during closure peritoneum and skin; requirement of postoperative analgesics: the first 6 hour in postoperative phase | |
Secondary | The correlation of requirement of postoperative analgesics for postoperative 48 hours and intraoperative nociception score | The consumption of patient controlled analgesia and intraoperative surgical pleth index score | intraoperative nociception score: 3 minutes during closure peritoneum and skin; requirement of postoperative analgesics: the first 48 hour in postoperative phase | |
Secondary | The correlation of postoperative pain score and intraoperative nociception score | The postoperative pain score (numeric rating pain score, no pain=0~ worst pain=10)and intraoperative surgical pleth index score | awaken after general anesthesia in post-anesthesia care unit , postoperative 6, 24, 48 hours | |
Secondary | The side effects of analgesics | nausea/vomiting, sedation, itching, respiratory depression | awaken after general anesthesia in post-anesthesia care unit , postoperative 6, 24, 48 hours |
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