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Analgesics clinical trials

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NCT ID: NCT06274814 Recruiting - Clinical trials for Breast Neoplasm Female

U/S Guided Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block vs Type 2 Pectoral Nerve Block

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare between U/S Guided Rhomboid Intercostal Block Combined with Sub-Serratus Plane Block vs type 2 Pectoral Nerve Block in Analgesia for Breast Cancer Surgery by measuring intraoperative hemodynamics, postoperative pain scores and morphine consumption in the first 24 h postoperative.

NCT ID: NCT05717361 Recruiting - Pain, Postoperative Clinical Trials

Opioid Sparing Anesthesia in Cervical Spine Surgery

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine surgery.

NCT ID: NCT05594407 Recruiting - Pain, Postoperative Clinical Trials

Opioid Sparing Anesthesia in Lumbar Spine Surgery

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus remifentanil analgesia in lumbar spine surgery

NCT ID: NCT05243940 Recruiting - Analgesia Clinical Trials

Opioid-free Anesthesia in Thyroidectomies

Start date: March 7, 2022
Phase: N/A
Study type: Interventional

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective thyroidectomies. Recovery parameters and nociception levels throughout the operation will be evaluated

NCT ID: NCT05089526 Recruiting - Pain, Postoperative Clinical Trials

Opioid-free Anesthesia in Laparoscopic Cholecystectomies

Start date: October 11, 2021
Phase: N/A
Study type: Interventional

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic cholecystectomies

NCT ID: NCT04879004 Recruiting - Pain Clinical Trials

EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial

EFFECT
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.

NCT ID: NCT04858711 Recruiting - Pain, Postoperative Clinical Trials

Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic gynecological surgery

NCT ID: NCT04705480 Recruiting - Pain Clinical Trials

Pregabalin vs. Gabapentin on Reducing Opioid Usage

Start date: April 12, 2021
Phase: Phase 4
Study type: Interventional

This is a single-center, randomized, open-label, Phase 4 clinical trial investigating the efficacy of multiple-dose administrations of Pregabalin or Gabapentin in combination with traditional opioid pain medications to decrease the amount of opioid pain medication usage in single-system orthopedic trauma patients.

NCT ID: NCT04622904 Recruiting - Pain, Postoperative Clinical Trials

Lidocaine and Magnesium and Ketamine in Gynecological Surgery

annie-sophia
Start date: November 14, 2020
Phase: N/A
Study type: Interventional

The aim of this study will be to investigate the effect of a combination of intravenous infusions of lidocaine and magnesium versus a combination of intravenous infusions of lidocaine and ketamine versus an intravenous infusion of lidocaine alone on recovery profile, quality of recovery and postoperative pain after elective gynecological surgery

NCT ID: NCT04489420 Terminated - Clinical trials for Glioblastoma Multiforme

Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM

CYNK001GBM01
Start date: October 1, 2020
Phase: Phase 1
Study type: Interventional

This study will find the maximum safe dose (MSD) or maximum tolerated dose (MTD) of CYNK-001 which are NK cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given after lymphodepleting chemotherapy for the systemic cohort (IV) (intravenous). The intratumoral cohort (IT) will not be giving lymphodepletion. The safety of this treatment will be evaluated, and researchers want to learn if NK cells will help in treating recurrent glioblastoma multiforme.