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Pain, Postoperative clinical trials

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NCT ID: NCT04508465 Enrolling by invitation - Clinical trials for Chronic Postoperative Pain

Persistent Postoperative Pain After Major Emergency Abdominal Surgery

Start date: June 4, 2020
Phase:
Study type: Observational

Perioperative pain is one of the most significant complaints and problems for patients undergoing major open surgery. Pain after surgery carry an abundance of consequences such as reduced mobilization, reduced nutrition intake, reduced pulmonary capacity and increased risk of complications and length of hospitalization. The literature does not supply much information on short- or longer-term outcomes of pain treatment for emergency surgery. The investigators know that for planned surgery in general around 10-50 percentage suffer from persistent postoperative pain. It is therefore important to follow-up on the longer-term outcomes after the standardized analgesic pain treatment. Based on a predefined patient group called OMEGA (Optimizing Major EMergency Abdominal surgery) the investigators hypothesize that OMEGA patients will present a significant incidence rate of patients with persistent postoperative pain and/or continued opioid/non-opioid usage. Therefore this study is to investigate the incidence of prolonged postoperative pain and opioid/non-opioid consumption in OMEGA patients at 3 month after major emergency abdominal surgery.

NCT ID: NCT04500613 Enrolling by invitation - Pain, Postoperative Clinical Trials

Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis

Start date: February 22, 2021
Phase: N/A
Study type: Interventional

Pediatric spinal fusion (PSF) surgery is a painful procedure that can treat adolescent idiopathic scoliosis (AIS). One technique that can potentially reduce patients' pain levels and need for opioid medication is the ultrasound-guided Erector Spinae Plane Block (ESPB). The ESP block is a technique that involves injecting an anesthetic medication into the muscles of the lower back on both sides of the spine. Previous studies have shown that ESPB application led to a reduction in opioid use, and there is one pediatric case report of ESPB use in two patients undergoing PSF. However, there is still lack of evidence that the ESPB technique is feasible and effective in the pediatric patient population. The present study is designed to be the first randomized controlled trial to evaluate the role of ESPB in pediatric spinal fusion surgery and the role of ESPB within an enhanced recovery pathway.

NCT ID: NCT04371445 Enrolling by invitation - Post-operative Pain Clinical Trials

Dextenza in the Post-op Management of Vitreoretinal Surgeries

Start date: December 1, 2020
Phase: Phase 4
Study type: Interventional

This study will assess the control of inflammation at days 1, 7, 14, and 21 days following the vitreoretinal surgical procedure analyzing two randomized study arms: Intracanalicular dexamethasone insert group or topical steroid drop group. Patients must be 18 years of age and older, of any race and either sex, requiring surgery with the procedure type of pars plana vitrectomy for either the indication of macular hole, epiretinal membrane removal, or vitreomacular traction.

NCT ID: NCT04346407 Enrolling by invitation - Post-operative Pain Clinical Trials

Dronabinol for Post-operative Pain After Lumbar Fusion

Start date: September 1, 2020
Phase: Phase 4
Study type: Interventional

Impact of 2.5mg of oral Dronabinol daily versus placebo on post-operative opioid consumption on patients aged 18 to 65 years old undergoing 1 to 3 level posterolateral fusion

NCT ID: NCT04280263 Enrolling by invitation - Pain, Postoperative Clinical Trials

Caffeine Study for Pain Control Following Total Joint Replacement

Start date: February 28, 2020
Phase: N/A
Study type: Interventional

A prospective, double blinded, single center, randomized controlled study to evaluate the efficacy of caffeine in combination with acetyl salicylic acid (ASA) in the management of postoperative pain in patients undergoing total joint arthroplasty.

NCT ID: NCT04278703 Enrolling by invitation - Pain, Postoperative Clinical Trials

Opioids Following ACL

Start date: February 15, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of a post-operative opioid pain 18 management protocol for anterior cruciate ligament reconstruction (ACLR).

NCT ID: NCT04260854 Enrolling by invitation - Pain, Postoperative Clinical Trials

Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery

Start date: January 24, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if the addition of bupivacaine HCl injections will improve pain control after skin surgery. This is a randomized clinical trial. Approximately 100 participants will be randomized to receive either bupivacaine HCl or saline injections to help with the postsurgical pain. Patients will be provided with a take-home journal to complete indicating when and how much pain medication they required for the 3 days immediately following surgery. Participants will return the journal in-person at a follow up visit 7-21 days post-op. This study was a pilot study designed to determine the feasibility of this procedure. Subjects currently living in the Chicago metropolitan area and meet inclusion/exclusion criteria will be invited and considered for enrollment.

NCT ID: NCT04217434 Enrolling by invitation - Pain, Postoperative Clinical Trials

Comparative Evaluation of Various Patient Centered Outcomes Following Gingival Depigmentation Using Diode LASER in Different Modes: A Randomized Clinical Trial

LASER
Start date: November 20, 2018
Phase: N/A
Study type: Interventional

Purpose of this study is to clinically evaluate and compare various patient centered outcomes using diode LASER in Continuous mode (CW) and Pulsed Mode (PM) using 300µm and 400µm fiber for depigmentation procedure.

NCT ID: NCT04115904 Enrolling by invitation - Pain, Postoperative Clinical Trials

Acute Pain Rate of Single Versus Two-visit Root Canal Treatment of Teeth With Necrotic Pulps

Acute pain
Start date: February 8, 2018
Phase: Phase 2
Study type: Interventional

Aim to compare acute pain rate after single-visit ortwo-visits treatment of teeth with necrotic pulp and apical periodontitis .90 teeth with a diagnosis of pulp necrosis and apical radiolucency at the apex.Working length was established with EAL and confirmed radiographically. Flex-R files were used to complete canal preparation. Level ofdiscomfort were recorded and cases with acute postoperative pain.

NCT ID: NCT04111081 Enrolling by invitation - Postoperative Pain Clinical Trials

Auricular Pressure for Postoperative Pain After Hemorrhoidectiomy: a Randomized Controlled Trial

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Auricular pressure is effective for postoperative analgesia after hemorrhoidectomy, but the evidence is not sufficient.