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Overweight and Obesity clinical trials

View clinical trials related to Overweight and Obesity.

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NCT ID: NCT06268262 Recruiting - Clinical trials for Overweight and Obesity

Surgical-imaging Research on Obesity (SIRO)

Start date: March 1, 2023
Phase:
Study type: Observational

The global obesity epidemic is well established, and is an important public health issue. The previous researches had applied the clues that obesity is a kind of systemic disease. The investigators hypothesized that a serious alteration of the body systems will occur after bariatric surgery, which may shed light on the mechanisms of obesity. Thus, the research aims to combine the imaging and surgery to investigate the alterations of the body that induced by obese and alterations after surgery.

NCT ID: NCT06256653 Recruiting - Obesity Clinical Trials

Assess the Effect of a Whole Fruit Powder on Gut Microbiome Function on Overweight & Obese Adults

Start date: January 29, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effect of freeze-dried blueberry powder on the gut microbiome in overweight and obese adults. The main question[s] it aims to answer are: - Does the supplementation of freeze-dried blueberry powder reduce the risk of obesity or lower the weight of people with a high BMI? - Does freeze-dried blueberry powder alter the gut microbiome function? Participants will; - Mix one sachet of Study Product (freeze-dried blueberry powder/placebo) into breakfast/dessert/yoghurt daily for 56 days during the intervention phase. - Partake in 4 site visits over the 14-week period, including an initial screening visit and a follow-up visit after the intervention phase. Researchers will compare the effect of freeze-dried blueberry powder with a placebo in a population comprising overweight and obese adults to see if the gut microbiome is altered and if there is a change in body composition.

NCT ID: NCT06253728 Recruiting - Clinical trials for Overweight and Obesity

A Study of Biochemical Response to Alternative Proteins

COBRA
Start date: January 18, 2024
Phase: N/A
Study type: Interventional

The overall objective of this research is to determine the digestive faith and health impact of protein and fiber rich foods in different food matrices in type 2 diabetes risk population. This is achieved by controlled postprandial intervention where plasma amino acids, lipids, glucose metabolism, bile acids and microbial metabolites are evaluated as well as fecal microbiota and metabolites.

NCT ID: NCT06250946 Not yet recruiting - Clinical trials for Overweight and Obesity

Efficacy and Safety of HRS-7535 Tablets in Obese Subjects .

Start date: February 2024
Phase: Phase 2
Study type: Interventional

The aim of this trial is to evaluate the efficacy and safety of HRS-7535 in Chinese Obese Subjects.

NCT ID: NCT06250647 Completed - Clinical trials for Overweight and Obesity

High Vitamin K Intake Diet Intervention Effect on Cardiovascular Risk Percentage in Young Adults

VKDI
Start date: February 6, 2021
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effect of a high vitamin K diet intervention on vitamin K, insulin, osteocalcin serum levels and the cardiovascular risk percentage in normal weight and overweight or obese young adults. The main questions it aims to answer are: • Does a diet intervention containing 500mcg of vitamin K increases serum vitamin K levels? • Are vitamin K serum levels after the 500mcg of vitamin K diet intervention associated with insulin and osteocalcin serum levels or the cardiovascular risk percentage in normal weight and overweight or obese young adults? Participants will have to follow a diet intervention that contains 500mcg of vitamin K, given as a cyclic menu for 6 weeks. Also, participants will have to assist weekly to nutritional monitoring and to report any situation they observed regarding the intervention during this study. Researchers will compare normal weight and overweight or obese groups with diet intervention with normal weight and overweight or obese groups without diet intervention and only dietetic recommendations to see if vitamin K serum levels, insulin, osteocalcin and the cardiovascular risk percentage improve after the 6 weeks diet intervention.

NCT ID: NCT06248307 Active, not recruiting - Clinical trials for Overweight and Obesity

Evaluation of Protein Bars on Weight Management and Osteoarthicular Health

COLARTIC
Start date: November 15, 2023
Phase: N/A
Study type: Interventional

The goal of this intervention study is to evaluate the efficacy in subjects with overweight or obesity of protein bars consumption. The main questions it aims to answer are: - Does the regular consumption of these protein bars help to loose weight? - Does the regular consumption of these protein bars help to improve the osteoarticular health? Participants will be asked to follow the indications of consumption of the bars togather with healthy nutritional advice during 16 weeks. Researchers will compare exparimental Versus placebo groups to see if weight is lost in similar or different ways.

NCT ID: NCT06245369 Recruiting - Clinical trials for Overweight and Obesity

SWITCH Diets Study: Self-monitoring With Internet Technology to Choose Healthy Diets

SWITCH
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of the Self-monitoring With Internet Technology to Choose Healthy Diets (SWITCH) study is to examine a 12-week remotely delivered program designed to help adults adopt a healthy dietary lifestyle and lose weight in a diverse cohort of adults with overweight/obesity. The intervention uses a self-determination theory framework to provide a deeper understanding of the factors that influence dietary behavior within the context of tracking. This study incorporates autonomy-supportive strategies to encourage participants to feel more in control of their dietary choices and will provide information and resources to boost participant's competence in achieving their dietary goals. The intervention includes weekly learning modules to support healthy eating and weight loss and daily dietary tracking with visual feedback, all accessible within the SWITCH app.

NCT ID: NCT06244888 Recruiting - Clinical trials for Overweight and Obesity

Control Systems Engineering for Weight Loss Maintenance

Start date: February 12, 2024
Phase: Phase 2
Study type: Interventional

This project capitalizes on principles of control systems engineering to build a dynamical model that predicts weight change during weight loss maintenance using behavioral, psychosocial, and environmental indicators evaluated in a system identification experiment. A 6-month behavioral obesity treatment will be administered to produce weight loss. Participants losing at least 3% of initial body weight will be followed for an additional 12 months via daily smartphone surveys that incorporates passive sensing to objectively monitor key behaviors. Survey data pertaining to behavioral, psychosocial, and environmental indicators will be used to develop a controller algorithm that can predict when an individual is entering a heightened period of risk for regain and why risk is elevated. Interventions targeting key risk indicators will be randomly administered during the system ID experiment. Survey and passive sensing data documenting the effects of the interventions will likewise drive development of the controller algorithm, allowing it to determine which interventions are most likely to counter risk of regain.

NCT ID: NCT06244186 Completed - Clinical trials for Overweight and Obesity

The Effect of Lactobacillus Delbrueckii Subsp. Bulgaricus on Human's Weight Reduction

Start date: September 10, 2021
Phase: N/A
Study type: Interventional

To evaluate the improvement in weight, body fat, and BMI after adding probiotics as a once-daily therapy for 84 days in overweight individuals.

NCT ID: NCT06242847 Recruiting - Psoriasis Clinical Trials

Role of Insulin Action in Psoriasis Pathogenesis

Start date: February 2, 2024
Phase:
Study type: Observational

The goal of this study is to collect more information from people with plaque psoriasis and to determine if insulin plays a role in the pathogenesis of psoriasis. The main question it aims to answer is if insulin action is preserved or even enhanced in psoriatic lesions despite insulin resistance elsewhere. Participants with plaque psoriasis will have punch biopsies taken of lesional and non-lesional skin after an overnight fast and then during an oral glucose tolerance test. Biopsy specimens will then be assessed for markers of insulin action.