Heart Failure With Reduced Ejection Fraction Clinical Trial
Official title:
A Virtual Heart Failure Optimization Program for Guideline Directed Medical Therapy and Cardiac Rehabilitation
The goal of this study is to test the impact of a virtual heart failure optimization program on uptake of guideline directed medical therapy, participation in cardiac rehabilitation & impact on echocardiographic parameters.
Status | Recruiting |
Enrollment | 400 |
Est. completion date | December 31, 2023 |
Est. primary completion date | December 31, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - HFrEF (ejection fraction less than 40%) with New York Heart Association (NYHA) class II or III symptoms - Adults (>18 years of age), capable of providing informed consent, English-proficient and with access to a telephone Exclusion Criteria: - Patients who are pregnant - Patients who who are incarcerated - Cardiac Transplant Patients - Patients with Left Ventricular Assist Devices |
Country | Name | City | State |
---|---|---|---|
Canada | Cambridge Cardiac Rehab | Cambridge | Ontario |
Lead Sponsor | Collaborator |
---|---|
Cambridge Cardiac Care Centre |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change from baseline Doses of GDMT | Beta-blocker, ACE-inhibitor/Angiotensin receptor blocker/Valsartan-Sacubitril, Mineralocorticoid Receptor Antagonist, SGLT2 inhibitor | After completion of program (3 months) | |
Primary | Change from baseline Left Ventricular Ejection Fraction | Measured in Transthoracic Echocardiogram | After completion of program (3 months) | |
Secondary | Change from baseline NYHA Classification | Stage of Heart Failure (I-IV, IV is worse) | After completion of program (3 months) | |
Secondary | Change from baseline Left Ventricular Mass Index | Measured by Transthoracic Echocardiogram | After completion of program (3 months) | |
Secondary | Change from baseline Left Ventricular End Diastolic Diameter | Measured by Transthoracic Echocardiogram | After completion of program (3 months) | |
Secondary | Change from baseline Left Ventricular End Systolic Diameter | Measured by Transthoracic Echocardiogram | After completion of program (3 months) | |
Secondary | Change from baseline Serum Potassium | After completion of program (3 months) | ||
Secondary | Change from baseline eGFR | After completion of program (3 months) | ||
Secondary | Change from baseline Systolic Blood Pressure | After completion of program (3 months) | ||
Secondary | Change from baseline Diastolic Blood Pressure | After completion of program (3 months) | ||
Secondary | Change from baseline Heart Rate | After completion of program (3 months) | ||
Secondary | Change from baseline Body Mass Index | After completion of program (3 months) |
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