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Clinical Trial Summary

This is an observational study for patients with prostate cancer that will be treated with Androgen Deprivation Therapy. The study will help the investigators learn more about how these medications affect the heart and how those effects relate to patients' medical history and social determinants of health (such as race, gender identity, education, occupation, access to health services and economic resources). Patients on this study will have echocardiograms, blood draws, and answer questions about their symptoms and activity level. Patients will be followed on this study for up to 5 years.


Clinical Trial Description

The investigators propose a prospective longitudinal cohort of prostate cancer patients treated with Androgen Deprivation Therapy (ADT) to determine the associations between social determinants of health (SDOH) and cardiotoxicity risk and to determine wither associations between SDOH and cardiotoxicity risk differs according to race. Patients will be followed with serial echo, blood draw, and surveys prior to start of ADT and then 6 months, 1 year, 2 years, 3 years, and 5 years after start of ADT. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05096338
Study type Observational
Source Abramson Cancer Center at Penn Medicine
Contact Bonnie Ky, MD, MSCE
Phone 215-573-6606
Email bonnie.ky@pennmedicine.upenn.edu
Status Recruiting
Phase
Start date October 27, 2021
Completion date October 2028

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