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NCT05060926 Clinical Trial

Intubation Prediction in COVID-19 Patients Treated With Awake Prone Positioning

Acute Hypoxemic Respiratory Failure Clinical Trial

— Intub_prone  

Official title:
Intubation Prediction in Sars-CoV-2 Patients Treated With Awake Prone Positioning

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05060926
Other study ID # Intub_prone
Secondary ID
Status Completed
Phase
First received
Last updated
Start date September 16, 2021
Est. completion date April 30, 2022

Study information
Verified date September 2021
Source University of Lausanne Hospitals
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Retrospective study in Sars-Cov 2 patients hospitalised in ICU. We aim to explore the effects of Awake prone positioning on oxygenation and intubation rate.

Recruitment information / eligibility
Status Completed
Enrollment 42
Est. completion date April 30, 2022
Est. primary completion date April 30, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Sars-CoV-2 pneumonia - ICU stay - Severe hypoxemia but non intubated Exclusion Criteria: - Intubated before admission - Denied consent for data analysis - Do not intubate order at ICU admission

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Awake prone positioning
Awake prone position as long as possible according to the patients' tolerance

Locations
Country Name City State
Switzerland Lausanne University Hospitals Lausanne Vaud

Sponsors (1)
Lead Sponsor Collaborator
University of Lausanne Hospitals

Country where clinical trial is conducted

Switzerland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Intubation rate Once between ICU admission and extubation
Secondary Alveolo-arterial gradient change Within 6 hours before and 6 hours after each pronation
Secondary Blood gas analysis Within 6 hours before and 6 hours after each pronation
Secondary Respiratory pattern Within 6 hours before and 6 hours after each pronation
Secondary Mortality Up to 28 days from ICU admission
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