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Clinical Trial Details — Status: Withdrawn

Administrative data

NCT number NCT02626663
Other study ID # RSRB00059370
Secondary ID
Status Withdrawn
Phase
First received
Last updated
Start date July 2016
Est. completion date December 2022

Study information

Verified date February 2019
Source University of Rochester
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The investigators propose to characterize MPs in aHUS and TTP both at the onset and throughout treatment. The investigators believe that the number, size, and cell origin of MPs will differ between these two diseases. The hypothesis is that endothelial derived MPs will be higher in number and comprise a larger portion of the MP population in aHUS and that platelet MPs will comprise a larger number and greater proportion of MPs in TTP. The investigators believe that MP identity and number can be used to reliably differentiate between aHUS and TTP at disease onset.


Recruitment information / eligibility

Status Withdrawn
Enrollment 0
Est. completion date December 2022
Est. primary completion date December 2020
Accepts healthy volunteers No
Gender All
Age group 18 Years to 120 Years
Eligibility Inclusion Criteria:

- Patients with MAHA, TTP, and/or aHUS

Exclusion Criteria:

- Prisoners

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
United States University of Rochester Medical Center Rochester New York

Sponsors (1)

Lead Sponsor Collaborator
University of Rochester

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary Microparticle/Nanoparticle number (an absolute number) an average of 3 months
Primary Microparticle/Nanoparticle size (in nanometers or micrometers) an average of 3 months
Primary Microparticle/Nanoparticle identity (identity of cell type from which they are derived) an average of 3 months
Secondary Morbidities 3 months
Secondary Mortality 3 months
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