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Other Cancer clinical trials

View clinical trials related to Other Cancer.

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NCT ID: NCT06103669 Recruiting - Breast Cancer Clinical Trials

Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

VALOROUS
Start date: October 5, 2023
Phase: N/A
Study type: Interventional

This is a phase 2 pragmatic study that evaluates the clinical benefit of continuing systemic therapy with the addition of locally ablative therapies for oligo-progressive solid tumors as the primary objective. The primary outcome measure is the time to treatment failure (defined as time to change in systemic failure or permanent discontinuation of therapy) following locally ablative therapy.

NCT ID: NCT05176860 Completed - Breast Cancer Clinical Trials

Evaluation of Novel Cone-Beam CT for Guidance and Adaptation of Precision Radiotherapy

Start date: December 20, 2022
Phase: N/A
Study type: Interventional

This is a feasibility study investigating the image quality of a new, high-performance cone beam CT (CBCT) used for on-couch imaging during radiotherapy treatments.

NCT ID: NCT04591431 Active, not recruiting - Breast Cancer Clinical Trials

The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy

ROME
Start date: October 7, 2020
Phase: Phase 2
Study type: Interventional

This is a randomized, prospective, multicenter, Proof of Concept, Phase II clinical trial Study. The main objective of the study is to evaluate the efficacy (meant as overall response rate ORR) of TT (targeted Therapy) vs SoC (standard of Care) in patients with progressive disease (recurrent and/or metastatic) of breast cancer, metastatic gastro-intestinal tumors, non small cell lung cancer (NSCLC) or others. Patients should have completed at least 1 line of treatment and no more than 2 as defined by the current version of the AIOM (Italian Association of Medical Oncology) guidelines. Patients are included if surgery is contraindicated.

NCT ID: NCT04585750 Recruiting - Breast Cancer Clinical Trials

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Start date: October 29, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This Phase 1/2 study will assess the safety, tolerability, and efficacy of multiple dose levels of PC14586 (INN: rezatapopt) alone (monotherapy) and in combination with pembrolizumab in participants with advanced solid tumors containing a TP53 Y220C mutation.

NCT ID: NCT04340024 Recruiting - Prostate Cancer Clinical Trials

Discovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer Patients

Start date: September 30, 2015
Phase:
Study type: Observational

Patients with cancers that are sensitive to radiotherapy treatment and/or patients who have experienced severe acute/ late side effects to radiotherapy will be recruited to the study. Blood and/or matched tumour-normal tissue pairs will be collected. Blood and/or tissue samples will be processed and studied for genetic and biochemical markers that have potential to be used for predicting sensitivity to radiation.

NCT ID: NCT03967379 Active, not recruiting - Other Cancer Clinical Trials

Multimodal Mobile Intervention Application (App) to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This research study is being done to evaluate whether the use of a mobile app can help transplant survivors experiencing sexual health problems.

NCT ID: NCT03850912 Active, not recruiting - Gynecologic Cancer Clinical Trials

Symptom Management Implementation of Patient Reported Outcomes in Oncology

SIMPRO
Start date: July 25, 2019
Phase: N/A
Study type: Interventional

Deficits in the management of common symptoms cause substantial morbidity for cancer patients.Because the health care delivery system is structured to be reactive and not proactive, there are missed opportunities to optimize symptom control. Growth in Internet access and proliferation of smartphones has created an opportunity to re-engineer cancer care delivery. Electronic symptom tracking and feedback is a promising strategy to improve symptom control. Electronic patient reported outcome (ePRO) monitoring of cancer symptoms has been shown to decrease symptom burden, improve quality of life, reduce acute care and even extend survival. SIMPRO will use functioning ePRO prototypes to create and refine the electronic symptom management system eSyM

NCT ID: NCT03752268 Active, not recruiting - Other Cancer Clinical Trials

Development of an Intervention to Enhance Cancer Pain Management

Start date: April 15, 2014
Phase: N/A
Study type: Interventional

This research study is being done to understand how patients with chronic cancer pain take their long-acting opioid medications, and to develop an intervention to enhance cancer pain management.

NCT ID: NCT03736746 Completed - Other Cancer Clinical Trials

Testing Feasibility of Motivational Interviewing for Patient-Reported Cancer Pain Goals

Start date: November 16, 2018
Phase: N/A
Study type: Interventional

This research study is evaluating the acceptability and feasibility of using a cognitive behavioral intervention called Motivational Interviewing to help persons with pain from cancer set goals for managing that pain.

NCT ID: NCT03721926 Completed - Other Cancer Clinical Trials

A Geriatric Oncology Collaborative Care Intervention for Older Adults With Advanced Cancer

Start date: February 14, 2019
Phase: N/A
Study type: Interventional

The purpose of this research study is to develop a geriatric oncology collaborative care intervention to enhance the quality of life, symptom burden, and functional outcomes of older adults with advanced gastrointestinal (GI) and genitourinary (GU) cancers.