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Osteoarthritis, Knee clinical trials

View clinical trials related to Osteoarthritis, Knee.

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NCT ID: NCT05398601 Completed - Knee Osteoarthritis Clinical Trials

Periosteal Electrical Dry Needling in Knee Osteoarthritis

Start date: September 14, 2022
Phase: N/A
Study type: Interventional

To determine the effect of periosteal electrical dry needling as an adjuvant to MWM in knee osteoarthritis for pain management, for improvement in functional activities and for ROM (Range Of Motion)

NCT ID: NCT05387135 Completed - Knee Osteoarthritis Clinical Trials

Transcutaneous Vagus Nerve Stimulation As a Pain Modulator in Knee Osteoarthritis

Start date: August 5, 2019
Phase: N/A
Study type: Interventional

a single-blinded, randomized clinical trial, 68 patients divided into 2 groups: active and sham treatment. Afferents of the Auricular branch of vagus nerve are stimulated using a transcutaneous Vagus Nerve Stimulation device (TENS 7000TM). The electrode was placed in the left cymba concha with direct contact on the skin. The stimulation for both groups will last for 30 minutes once a day for 3 days per week for 12 weeks. The amplitude of the output current was between 0.25-2.0 mA as tolerated and 250 µs width at 25 Hz. All participants initially will be evaluated before and after intervention and 3 months after the end of the sessions.

NCT ID: NCT05382429 Completed - Knee Osteoarthritis Clinical Trials

Observation of the Clinical Efficacy of Two Surgical Procedures for Varus Knee Osteoarthritis

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct a prospective randomized controlled trial to compare the effects between two surgical procedures in the treatment of varus knee osteoarthritis.The hypothesis was that there would be no difference in mechanical axis correction between two surgical procedures.

NCT ID: NCT05380648 Completed - Clinical trials for Osteoarthritis, Knee

Predicting Outcome of Total Knee Replacement Surgery in Patients With Knee Osteoarthritis

Start date: March 8, 2018
Phase:
Study type: Observational [Patient Registry]

Osteoarthritis (OA) is the main cause of pain and disability in elderly. For knee OA, a total knee replacement (TKR) is an effective surgical treatment, and the majority of patients report substantial pain relief and functional improvement following surgery. However, 20-40% of patients undergoing TKR are dissatisfied with postsurgical outcome. Even after revision, some patients keep complaining of persisting pain. In this study, the investigators will examine putative prognostic factors on the basis of the biopsychosocial model. Besides several psychological factors (measured with questionnaires), the investigators will assess structural impairments (such as radiographic severity of OA), functional impairments (muscle weakness and proprioceptive deficits), anesthetic procedures, immediate postoperative pain management, metabolic factors (body composition and hemoglobin A1c), inflammatory factors (C-Reactive Protein) and the investigators also will examine the role of altered central pain processing (CPP) (primary and secondary mechanical hyperalgesia, mechanical temporal summation, thermal primary and secondary hyperalgesia, endogenous pain modulation). With a longitudinal study design, this study will explore which factors are predictive of poor outcome in knee OA patients after TKR. Moreover, the interrelationship between CPP, structural, functional, metabolic, inflammatory and psychological factors, and the clinical expression of knee OA (pain, symptoms, physical performance and quality of life) will be investigated. Further research on the role of the aforementioned putative prognostic factors on postsurgical outcome could contribute to better management of these patients, since these factors may be particularly important for patient-tailored treatment.

NCT ID: NCT05380206 Completed - Clinical trials for Osteoarthritis, Knee

Functional Knee Phenotypes of Patients Operated on for Total Knee Arthroplasty

FP-Knee
Start date: March 15, 2021
Phase:
Study type: Observational

The aim of this study was to analyze the coronal alignment of a large population of patients undergoing total knee arthroplasty using a modern classification of the knee phenotypes found in a population of non-osteoarthritic patients.

NCT ID: NCT05365061 Completed - Knee Osteoarthritis Clinical Trials

Periosteal Electrical Dry Needling for Knee Osteoarthritis

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this research is to treat patients with knee osteoarthritis (OA) with periosteal electric dry needling (PEDN). It is also to determine the optimal "maintenance" regiment (i.e. maintenance treatments, one maintenance treatment every other month, or one maintenance treatment per month) required to maintain improvements in pain and function following PEDN. Physical therapists commonly use PEDN to treat knee OA, and previous studies suggest that this treatment is useful for reducing pain and improving function in patients with osteoarthritis. However, an appropriate maintenance treatment strategy to maintain these outcomes is presently unknown.

NCT ID: NCT05360329 Completed - Knee Osteoarthritis Clinical Trials

Genicular Artery Embolization as Pain Treatment of Knee Osteoarthritis

GETKO
Start date: September 20, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the safety and efficacy of geniculate artery embolization (GAE) as pain treatment in patients with mild to moderate knee osteoarthritis.

NCT ID: NCT05351996 Completed - Clinical trials for Osteoarthritis, Knee

Kinesiotaping in Knee Osteoarthritis

Start date: November 20, 2019
Phase: N/A
Study type: Interventional

Kinesiotape is one of the treatment choices for the patients with knee osteoarthritis. Unlike the brace, it seems to be an important advantage in kinesiotape application in that it permits the movement of the joint. However, kinesiotape is conditionally recommended for knee osteoarthritis in the 2019 American College of Rheumatology treatment recommendations due to limiting the quality of evidence, using various application methods, and the lack of blindness concerning its use is not possible. The aim of the study is to determine the effects of kinesiotaping on pain, physical performance, knee range of motion, and postural stability in knee osteoarthritis.

NCT ID: NCT05349565 Completed - Knee Osteoarthritis Clinical Trials

Effects of Muscle Energy Technique in Knee Osteoarthritis Patients

Start date: September 13, 2022
Phase: N/A
Study type: Interventional

To determine the effectiveness of muscle energy technique along conventional physical therapy after mesenchymal stem cell transplantation in knee Osteoarthritis patients regarding Pain, range of motion, functional disability and quality of life.

NCT ID: NCT05349500 Completed - Obesity Clinical Trials

OA Clinic-Community CARE Model

OA CARE
Start date: June 7, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to test the OA Clinic-Community CARE Model (OA CARE) which will address all recommended components of knee/hip (osteoarthritis) OA care, include interventions for both patients and primary care providers (PCPs), and utilize a tailored approach that efficiently matches treatments with patients' needs. The patient component of OA CARE will include evidence-based weight management and exercise programs for all participants (delivered through the YMCA), as well as tailored referrals to physical therapy, additional weight management or nutrition services, sleep-related services and psychological services. The PCP component of OA CARE will include a video-based summary of current OA treatment guidelines (with emphasis on practical application), collaboration on patients' referrals to specific services described above, and progress reports on enrolled patients.