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Osteoarthritis, Knee clinical trials

View clinical trials related to Osteoarthritis, Knee.

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NCT ID: NCT06233630 Recruiting - Knee Osteoarthritis Clinical Trials

Erector Spinae Plane Block vs. iPACK Block With Adductor Canal Block for Total Knee Arthroplasty

Start date: March 30, 2024
Phase: Phase 4
Study type: Interventional

Effect of Erector Spinae Plane Block and iPACK block with Adductor Canal Block on pain management, and NLR and PLR following knee arthroplasty

NCT ID: NCT06233474 Recruiting - Clinical trials for Osteoarthritis, Knee

Study of Intra-articular Allocetra in Knee Osteoarthritis

Start date: January 26, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This is a double blind, randomized,multi-center study to evaluate the safety and efficacy of intra-articular administration of Allocetra compared to placebo in patients with symptomatic knee osteoarthritis.

NCT ID: NCT06233175 Recruiting - Knee Osteoarthritis Clinical Trials

Combined Kinetic Chain Exercises on Knee Osteoarthritis

Start date: January 30, 2024
Phase: N/A
Study type: Interventional

study will be conducted at faculty of physical therapy cairo university to investigate the effect of combined kinetic chain exercises on static and dynamic hamstring and quadriceps strength in knee osteoarthritis patients

NCT ID: NCT06232018 Active, not recruiting - OsteoArthritis Knee Clinical Trials

A Comparison of 2-octyl Cyanoacrylate Skin Adhesive and Polyester Mesh for Wound Closure in Total Knee Arthroplasty, A Randomized Controlled Study

Start date: September 28, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized controlled study is to investigate the Efficacy of Using skin adhesive (Dermabond) and skin adhesive with polyester mesh (Dermabond Prineo )for Wound Closure in Total Knee Arthroplasty, The main question it aim to answer 1 Are skin adhesive alone and with Polyester mesh in Total knee arthroplasty different in Patient satisfaction evaluated by POSAS score

NCT ID: NCT06231758 Recruiting - Clinical trials for Osteo Arthritis Knee

Metformin Safety and Efficacy in Osteoarthritis.

Start date: January 30, 2024
Phase: Phase 3
Study type: Interventional

Knee osteoarthritis (OA) is a chronic, painful disease associated with considerable morbidity, costs and disability. It is estimated that over a third of people aged over 60 have radiographic knee OA2 and over 50% of these with knee OA will go on to have a total knee replacement in their lifetime. At present there are no licensed treatments that alter disease progress and management is primarily concerned with symptom control to retain or improve joint function, although a trial of strontium ranelate showed promising results.

NCT ID: NCT06230081 Recruiting - Clinical trials for Osteoarthritis of the Knee or Hip

Comparison Between Blocks or Not in Joint Arthroplasty

BLAST
Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect on postoperative pain, opioid consumption and function by adding a combination of regional blocks with local anaesthetic before total hip- and knee arthroplasty compared to standard pain management strategies.

NCT ID: NCT06229951 Not yet recruiting - Clinical trials for Osteo Arthritis Knee

Hydrolyzed Collagen and Undenatured Collagen Type II in OA Knee

Start date: January 20, 2024
Phase: N/A
Study type: Interventional

Randomized controlled trial Targeted patients who come to receive treatment for osteoarthritis that meets the research indications will be assigned to a random group by the box of 4 randomization method, with a sequence that is randomly generated by a computer. The groups are divided into two groups: Group 1: Patients who have taken 480 mg of hydrolyzed collagen and 20 mg of undenatured type II collagen Group 2: Control patients will take placebo Primary outcome : Pain level

NCT ID: NCT06229691 Recruiting - Clinical trials for Osteoarthritis, Knee

Muscle Fatigability and Trip-specific Fall Risk in Adults With Knee Osteoarthritis

Start date: May 2, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about how fatigue affects the risk of falling in adults aged 55-70 years with and without knee osteoarthritis. The main questions this trial aims to answer are: - Does fatigue increase the risk of tripping while walking? and - Does fatigue increase the risk of falling in response to a trip while walking? Participants will - Complete questionnaires - Wear a device that measures physical activity for 5-7 days - Complete a 30 minute walk on a treadmill - Complete the following before and after the treadmill walk: - Computer test to measure mental fatigue - Maximal strength testing - Balance test Researchers will compare adults with and without knee osteoarthritis to see if fall risk in adults with knee osteoarthritis is affected more by walking activity compared to adults without knee osteoarthritis.

NCT ID: NCT06228911 Completed - Clinical trials for Osteoarthritis, Knee

Increased Blood Glucose Levels After Steroid Injection

Start date: January 15, 2020
Phase: N/A
Study type: Interventional

a sample of 600 patients diagnosed as Knee osteoarthritis injected with 40 mg triamcinolone, recorded their morning fasting blood glucose levels for 7 days before injection used as the baseline blood glucose level, which was compared with FBS levels for 14 days after steroid injection. Our study compared the differences in blood glucose changes between HbA1c >7% and HbA1c ≤7% groups and those between insulin and non-insulin treated groups.

NCT ID: NCT06228573 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

Start date: May 15, 2024
Phase: N/A
Study type: Interventional

People with knee arthritis often experience constant pain, and current treatments aren't very effective. This can lead to limited movement and more health problems. Knee arthritis is a big part of healthcare costs in Canada, and its pain is a major reason people see doctors. The pain is linked to complex nervous system changes, making current treatments, like exercise, not very successful. To address this, researchers suggest a new approach combining two things: a brain stimulation technique called Transcranial Direct Current Stimulation (tDCS) and yoga. TDCS helps with pain by changing how the brain works, and yoga, a safe practice, focuses on overall well-being. Together, the investigators aim to improve how the nervous system works from top to bottom. The research project wants to change how the arthritis pain is being managed by focusing on how it works. The investigators plan to test this combo in a study comparing real tDCS plus yoga with fake tDCS plus yoga. The investigators will look not only at pain but also at other measures related to pain and how the nervous system works. This new mix could be a meaningful way to reduce pain for people with knee arthritis.