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Metformin Safety and Efficacy in Osteoarthritis.

Osteo Arthritis Knee Clinical Trial

Official title:
The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis

Clinical Trial Summary

Knee osteoarthritis (OA) is a chronic, painful disease associated with considerable morbidity, costs and disability. It is estimated that over a third of people aged over 60 have radiographic knee OA2 and over 50% of these with knee OA will go on to have a total knee replacement in their lifetime. At present there are no licensed treatments that alter disease progress and management is primarily concerned with symptom control to retain or improve joint function, although a trial of strontium ranelate showed promising results.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06231758
Study type Interventional
Source Tanta University
Contact Mostafa Bahaa
Phone +201025538337
Email mbahaa@horus.edu.eg
Status Recruiting
Phase Phase 3
Start date January 30, 2024
Completion date September 20, 2027
View Details
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