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Osteoarthritis, Hip clinical trials

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NCT ID: NCT06282666 Not yet recruiting - Quality of Life Clinical Trials

Lumbar ESPB in Hip Replacement Surgery

ESPB_HIP
Start date: February 19, 2024
Phase: N/A
Study type: Interventional

In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery. Opioid consumption, pain severity, quadriceps femoris muscle strength, ability to walk, and quality of recovery will be evaluated. Moreover, chronic pain severity in months after the hospital discharge will be assessed.

NCT ID: NCT06272422 Not yet recruiting - Coxarthrosis Clinical Trials

Comparison of the Restoration of Hip Biomechanical Parameters by CT Measurement Between the 3 Surgical Techniques: RSA/Minihip/THA - Hip Replacement: 3D Planning

HIP3D
Start date: March 2024
Phase:
Study type: Observational

The study will analyze hip biomechanical parameters using EOS radiographic measurements pre- and post-operatively (3 months) and post-operatively (3 months) CT scans after total hip replacement (THR), neck-preserving THR of the Minihip type or hip resurfacing (HR). Clinical results will be assessed at 3 months and 1 year after surgery. To this end, two types of examination are carried out, both of which are used in current practice: - Pre-operatively: EOS radiography - Post-operatively: EOS radiograph and CT scan Inclusion (m-3; m-1) : - Patient information at pre-operative visit - Non-opposition of patient, family member or legal guardian, if applicable - Questionnaires and clinical examination (standard management) - EOS during anesthetic consultation Follow-up visit (m+3): - Post-operative follow-up consultation EOS and CT scan (1 week prior to visit) + questionnaire and clinical examination Follow-up visit (m+12): - Post-operative check-up, questionnaire and clinical examination

NCT ID: NCT06258369 Not yet recruiting - Clinical trials for Primary; Coxarthrosis

Gait Initiation and Transition From Double to Single Support in Patients With Unilateral Primary Coxarthrosis

COXAM
Start date: February 2024
Phase: N/A
Study type: Interventional

The study consists to evaluate the impact of prosthetic surgery (PTH and RTH) on kinematic and dynamic parameters (joint torques) of the lower limbs during gait initiation in patients with primary coxarthrosis. Patients included in the study will undergo a three-dimensional gait analysis. Dynamic gait analysis is multidimensional, measuring kinematic parameters (joint amplitudes: ankles, knees, hips, etc.) and dynamic parameters (assessment of joint torque from ankle, knee, hip to lower limb during gait initiation).

NCT ID: NCT06257160 Not yet recruiting - Hip Arthropathy Clinical Trials

Superiority Randomized Controlled Trial of Ultrasound-guided PENG Block Compared to Surgical Infiltration in the Analgesia of Posterior Total Hip Arthroplasty Surgery

PENGORINF
Start date: March 2024
Phase: N/A
Study type: Interventional

Pain after total hip replacement (THR) surgery is severe. The target population is elderly and comorbid. Level III analgesics are responsible for significant side effects in this population. Locoregional analgesia, by reducing the consumption of painkillers, is an effective way of reducing morphine or morphine agonist consumption in this surgery. Furthermore, these techniques fit in perfectly with the objectives of accelerated rehabilitation after surgery. Surgical infiltration is a frequently used and effective analgesic technique. PENG block is a new locoregional anesthesia technique which initial results show promising analgesic efficacy and the absence of loss of strength through motor block. In February 2022, we carried out a survey of national anesthetic practices in posterior hip arthroplasty, with the help of the SFAR (Société Française d'Anesthésie-Réanimation). It shows that, despite the lack of plentiful literature on the subject, the PENG block is currently the most frequently performed pre-operative block in hip arthroplasty (PENG block in 39.5% of cases, femoral block in 13% of cases). The survey also shows that in 41.5% of cases, no block is performed, and only intraoperative surgical infiltration is carried out. PENG block and surgical infiltration are therefore the two analgesic techniques most frequently used in France today. It is for these reasons that we feel it is essential to carry out a study comparing these two techniques.

NCT ID: NCT06187116 Not yet recruiting - Clinical trials for Osteoarthritis, Knee

Physiotherapist Led Triage in Primary Care for Patients With Hip or Knee OA

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The overall aim with the study is to evaluate physiotherapist led triage in primary care compared to usual care (assessment by an orthopaedic surgeon in an orthopaedic department) for patients with hip or knee osteoarthritis referred for orthopaedic consultation.

NCT ID: NCT06186115 Not yet recruiting - Osteoarthritis, Hip Clinical Trials

Intraarticular Gold Microparticles for Hip Osteoarthritis

Start date: March 4, 2024
Phase:
Study type: Observational

In a pilot study, the investigators recently showed that intraarticular metallic gold microparticles reduce knee osteoarthritis pain for up to two years and found associated significant proteomic changes in serum and synovial fluid within eight weeks. This study aim to evaluate the outcome after intra-articular injection of gold microparticles for hip osteoarthritis.

NCT ID: NCT06173713 Not yet recruiting - Hip Osteoarthritis Clinical Trials

Emphasys Radiostereometric Analysis

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This study is designed as a prospective, multi-centre, non-randomized, non-controlled study. This study does not limit the procedures involved in the treatment of the subject as long as the protocol specified products are utilized. The primary objective is to establish the mean superior cup migration of the Emphasys Shell and the mean inferior stem migration of the Emphasys Stem using model-based RSA over the first two years post-implantation. Additionally, the data from this study will be compared to historical Pinnacle Acetabular Shell data obtained in study DSJ_2018_02.

NCT ID: NCT06162195 Not yet recruiting - Osteoarthritis, Hip Clinical Trials

The ACTIVE Trial: A Prospective Randomised Control Trial Of The H1 Implant Versus Total Hip Replacement

ACTIVE
Start date: September 2024
Phase: N/A
Study type: Interventional

The goal of this randomised controlled trial is to compare the success of two types of hip replacement in patients with hip arthritis. The main question it aims to answer is whether a new type of hip replacement (called a hip resurfacing) can be as successful as an existing hip replacement (called a total hip replacement). Patients will be given either the new hip resurfacing or the existing total hip replacement and researchers will compare their function, complication rate and physical activity.

NCT ID: NCT06145516 Not yet recruiting - Surgery Clinical Trials

Promoting Sleep to Alleviate Pain - Arthroplasty

PROSAP-A
Start date: January 2024
Phase: N/A
Study type: Interventional

PROSAP-A is a perioperative randomized, controlled trial with a 12-month follow-up period after total knee arthroplasty (TKA) or total hip arthroplasty (THA), aiming to investigate both acute and long-term postoperative effects of preoperative sleep-promotion. Participants with clinically significant insomnia symptoms will be randomized to a brief, hybrid version of cognitive behavioral therapy for insomnia (CBT-I) or sleep education therapy, administered over a 4-week period, prior to surgery. The primary objectives are to evaluate effects of preoperative sleep-promotion on acute and long-term postoperative pain control. Secondary objectives include evaluation of postoperative sleep, recovery, mental health, cognitive function and alterations in blood biomarkers.

NCT ID: NCT06144099 Not yet recruiting - Prostate Cancer Clinical Trials

Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac Surgery

Start date: March 1, 2024
Phase: Phase 4
Study type: Interventional

The primary endpoint of this study is the completion time of hemostasis treatment when administered Fresh frozen plasma (FFP) and frozen powder coagulation factor concentrate (PCC) in goal-directed bleeding management for non-cardiac surgery.