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Osteoarthritis, Hip clinical trials

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NCT ID: NCT04241354 Recruiting - Osteoarthritis Clinical Trials

A Comparison of PRP Treatment to the IA vs. IA and EA Environments in Patients Diagnosed With Hip Osteoarthritis

Start date: August 25, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the efficacy of one leukocyte-poor platelet-rich plasma (LP-PRP) injection to the intra-articular (IA) space in comparison to one LP-PRP injection to the IA space with an additional injection into the surrounding extra-articular (EA) structures for the treatment of hip OA (Kellgren Lawrence Grades 1-3). Our hypothesis is that patients receiving both IA and EA LP-PRP injections will have equivalent improvements on HOOS JR and VAS scores over a 12-month period compared to those in the active comparator group (IA LP-PRP injection).

NCT ID: NCT04238143 Recruiting - Osteoarthritis Clinical Trials

Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis

GARM-MSK-ALD
Start date: January 10, 2020
Phase: N/A
Study type: Interventional

Use of Biocellular and cellular approaches to treatment of Osteoarthritis (OA), musculoskeletal aging processes, pain, and degenerative changes are to be studied with minimally invasive protocols, and non-pharmaceutical means to relieve OA and its associated issues. Traditional surgical interventions have not yielded convincing long-term outcomes, including total joint replacement surgeries and medical management of the supportive structures. This study is to use a person's own stem/stromal Cells (autologous) plus HD-PRP (important healing growth factors and signal molecules) in such cases of OA for long-term minimally invasive treatments. Baseline (existing) findings are documented, and thence tracked as to progress deemed to be result of the intervention.

NCT ID: NCT04221425 Completed - Osteoarthritis, Hip Clinical Trials

Early Virtual Reality Based Home Rehabilitation Program After Total Hip Arthroplasty

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Total hip replacement (THR) is one of the most common interventions in orthopedic surgery. Rehabilitation is essential for maximizing the effectiveness of the surgery. Tele-rehabilitation programs after orthopedic surgery have proven their effectiveness, validity and cost-efficacy. It seems of interest to test the potential advantages of early virtual reality based rehabilitation programs after total hip arthroplasty compared to standard care. The aim of the study is to evaluate the functional recovery following total hip arthroplasty and home telerehabilitation programs with a virtual reality based system.

NCT ID: NCT04214171 Completed - Hip Osteoarthritis Clinical Trials

Kinematics and Muscle Strength in Two, Five or 10 Years Afther Total Hip Arthroplasty

Arthroplasty
Start date: January 1, 2017
Phase:
Study type: Observational [Patient Registry]

Introduction: Femoral and acetabular replacement is characterized as total hip arthroplasty (THA). It has been used as treatment of various pathologies of this joint. In the postoperative period, some studies have shown that strength, function, range of motion and lower limb mechanics remains altered for more than One year after THA in relation to the non-operated side. However, studies that have correlated kinematics and hip muscle strength in individuals who underwent THA for long time, do not exist in literature. Objective: to evaluate lower limb muscle strength and 2D kinematics during stair ascending and descending in patients undergoing total hip arthroplasty. Methods: Third individuals who underwent total hip arthroplasty (THA) will be recruited at two, five and 10 year postoperative periods. They were allocated in three groups: Group 1 (10n), subjects submitted to THA for two years, Group 2 (10n) subjects submitted to THA for five years, Group 3 (10n) subjects submitted to THA for 10 years and Group 4 (10n) subjects without orthopaedic afections, all will be evaluated for dynamometric isometric muscle strength and kinematic analysis of stair ascending and descending by a "blinded" physical Therapist.

NCT ID: NCT04212650 Terminated - Hip Osteoarthritis Clinical Trials

Losartan to Improve Hip Microfracture

Start date: August 7, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Phase I/IIA randomized, double-blind, placebo-controlled clinical trial to assess safety and efficacy of oral losartan for improving cartilage repair following microfracture to treat focal cartilage defects during hip arthroscopy.

NCT ID: NCT04211987 Completed - Hip Osteoarthritis Clinical Trials

Fast Track Total Hip Arthroplasty vs Standard Care

FastTrack-H
Start date: March 13, 2018
Phase: N/A
Study type: Interventional

Fast-track total hip arthroplasty (THA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery. The aim of this protocol is to compare the standard care and fast track total hip arthroplasties in terms of functional and subjective outcomes, hospital staying, number of transfusions and analgesic consumption.

NCT ID: NCT04206722 Completed - Hip Osteoarthritis Clinical Trials

Efficiency of Shock-wave Therapy in Symptomatic Hip Osteoarthritis

Start date: June 2012
Phase: N/A
Study type: Interventional

The objectives of treatment in hip osteoarthritis are pain relief, improve joint range of motion and muscle force, gait rehabilitation, patient education and socio-professional reintegration.The non-pharmacological and non-surgical methods include certain types of physical therapy: massage, heat, ultrasound, laser, shockwave therapy. Few studies have been conducted so far for outcome measurement in symptomatic hip osteoarthritis.

NCT ID: NCT04204083 Completed - Osteoarthritis, Hip Clinical Trials

MONOVISC for Hip Joint Pain Relief

Start date: December 17, 2019
Phase: N/A
Study type: Interventional

Obtain real world, post market data to confirm the clinical improvement and safety in patients treated with a single injection of MONOVISC for the symptomatic relief of osteoarthritis in the hip joint.

NCT ID: NCT04203732 Completed - Clinical trials for Osteoarthritis, Knee

Evaluation of Anesthetic Techniques in Outpatient Total Joint Replacement Surgery in an Integrated Health Care Delivery System

Start date: January 1, 2020
Phase:
Study type: Observational

The study is a retrospective cohort study of adult patients undergoing outpatient primary unilateral total knee or total hip replacement surgeries from 2017 to 2019 assessing for difference in anesthetic techniques and outcomes.

NCT ID: NCT04199390 Completed - Surgery Clinical Trials

Physical Therapy Following Total Hip Arthroplasty

Start date: July 31, 2018
Phase: N/A
Study type: Interventional

130 patients undergoing primary unilateral total hip arthroplasty through anterior approach were enrolled and randomized into one of two groups. One group received standard of care clinic-based physical therapy postoperatively (clinic PT) while the other group underwent progressive home-based exercises to do after surgery (home PT). Patient surveys with Hip Osteoarthritis Outcome Scores (HOOS) and SF12v2 scores for both groups were obtained before surgery as well as 6, 14, and 24 weeks postop. Patients had the option to crossover into the other study group at their 6-week follow-up visit.