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Brain Outcomes With Lifestyle Change in Down Syndrome — BOLD  

Obesity Clinical Trial

Official title:
The Impact of Weight Loss on Alzheimer's Disease Risk in Adults With Down Syndrome

Clinical Trial Summary

The goal of this study is to determine if weight loss or changes can help prevent of delay adults with Down syndrome from developing Alzheimer's Disease Adults with Down syndrome without dementia will be randomized to either a weight loss group or a general health education control group. The weight loss group will be asked to follow a reduced energy diet, attend monthly education sessions delivered remotely and self-monitor diet and body weight using commercially available web-based applications. The control group will be asked to attend remotely delivered monthly education sessions on general health education topics. All participants will come to the University of Kansas Medical Center, 3 times across 12 months for a blood draw, cognitive testing, a MRI, assessment of height and weight, and assessment of diet intake.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05985486
Study type Interventional
Source University of Kansas Medical Center
Contact Lauren Ptomey, PhD
Phone 913-588-7982
Email lptomey@kumc.edu
Status Not yet recruiting
Phase N/A
Start date October 1, 2024
Completion date September 30, 2027
View Details
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