Obesity Clinical Trial
Official title:
Dose-response Effects of Exercise on Abdominal Obesity and Risk Factors for CVD in Men and Women.
The investigators will randomize abdominally obese men and women at increased health risk to
one of the following 4 conditions: 1) No-exercise, wait list controls (C), 2) Low volume,
low intensity exercise (LVLI), 3) High volume, low intensity exercise (HVLI), 4) Low volume,
high intensity exercise (LVHI).
The primary aim of the trial is to determine the effects of varying exercise dose (energy
expenditure, kcal) or intensity (relative to VO2max (cardiorespiratory fitness)) on waist
circumference and glucose tolerance. The investigators will test the following hypotheses:
1) That the reduction in waist circumference and improvement in glucose tolerance in
response to all treatments will be greater than controls. 2) That reduction in waist
circumference and improvement in glucose tolerance in HVLI and LVHI will be greater than
LVLI. 3) That hypotheses 1 and 2 are true independent of gender.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
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