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Obesity, Morbid clinical trials

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NCT ID: NCT05620641 Recruiting - Morbid Obesity Clinical Trials

Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy

Start date: October 1, 2022
Phase: Phase 3
Study type: Interventional

The aim of this study is to compare the possible efficacy of ondansetron and gabapentin on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.

NCT ID: NCT05611697 Recruiting - Obesity, Morbid Clinical Trials

Laparoscopic Single Anastomosis Sleeve Ileal Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity

Start date: February 17, 2023
Phase: N/A
Study type: Interventional

This study will compare two bariatric surgical interventions in terms of weight loss, gastroesophageal reflux, and effects on obesity-related comorbid conditions in morbidly obese patients.

NCT ID: NCT05608031 Completed - Surgery Clinical Trials

6th Month EWL% After Sleeve Gastrectomy to Get a Better Sleep Quality

Start date: January 1, 2018
Phase:
Study type: Observational

Obesity, caused by caloric intake over output, has become a global health problem. The relationship between sleep and obesity is widely discussed in the literature. Little is known regarding the compliance of sleep quality and patients' weight loss. This study aimed to review how sleep quality is affected by bariatric surgery, examine whether compliance with sleep quality can be predicted after bariatric surgery, and assess its correlation with excess weight loss.

NCT ID: NCT05603338 Completed - Obesity, Morbid Clinical Trials

Naturally Banded Sleeve Gastrectomy

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

the idea is to use an omental flap or round ligament as a natural band in stead of synesthetic band in bariatric procedures, mainly gastric sleeve

NCT ID: NCT05598840 Completed - Weight Loss Clinical Trials

Efficacy of a Mobile Application to Help in Weight Loss Before Bariatric Surgery

VAMOS
Start date: October 18, 2022
Phase: N/A
Study type: Interventional

The present randomized clinical trial aims to prove the safety and efficacy of an interactive mobile application (Care4Today®) to obtain sufficient weight loss and empower patients with morbid obesity before being submitted to a gastric by-pass.

NCT ID: NCT05591898 Enrolling by invitation - Anxiety Clinical Trials

The Effect of Progressive Relaxation Exercises on Bariatric Surgery Period

PREbari
Start date: January 15, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the effect of the progressive relaxation exercises in perioperative bariatric surgery patient care. The investigators know that the preoperative anxiety is an important factor that affects acute postoperative pain experience. Additionally, the investigators know that there is a relationship between preoperative anxiety and moderate to severe pain in the first 12 hours postoperatively, and this is also true for patients undergoing bariatric surgery. The main questions it aims to answer are: - Does preoperative anxiety level of patient who will undergo bariatric surgery and who are applied progressive relaxation exercises is lower than those who did not apply exercise? - Does postoperative pain level of patient who underwent bariatric surgery and applied progressive relaxation exercises was lower than patients who did not apply exercise? Participants will be randomly split into two groups and one of the groups of participants will learn how to do progressive relaxation exercises preoperatively and the other group will learn nothing. Then at the time of the surgery, all participants will fill a survey preoperatively to analyze participants' anxiety level in each group and the investigators will collect data about participants' pain level postoperatively. Researchers will compare these data whether there is an effect of the progressive relaxation exercises on preoperative anxiety and postoperative pain or not.

NCT ID: NCT05591833 Completed - Obesity, Morbid Clinical Trials

Single Anastomosis Sleeve Ileal Bypass Versus Single Anastomosis Sleeve Jejunal Bypass

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

to compare the results of SASI to SAS-J in treatment of morbid obesity

NCT ID: NCT05591105 Completed - Opioid Use Clinical Trials

Morphine Consumption in the Obese Patients

Start date: June 15, 2023
Phase:
Study type: Observational

The goal of this observational study is to evaluate the quality of postoperative analgesia in a group of obese patients schedule to bariatric surgery under TIVA Opiod-free after to receive lidocaine and ketamine perfusion. The main question it aims to answer are: How lidocaine and ketamine perfusion during recovery period does impact over morphine consumption on the following 48 hours after surgery? All participants will receive total intravenous anesthesia and, at the end of the surgery, they will be divided in two groups, group A: placebo and, group B: with postoperative lidocaine and ketamine perfusion. Our hypothesis is ketamine and lidocaine are a good alternative to decrease the use of morphine in obese patients.

NCT ID: NCT05590208 Completed - Obesity, Morbid Clinical Trials

Sleeve Gastrectomy With Cruroplasty and Omental Rape for Treatment of Morbid Obesity With Reflux Disease

Start date: October 12, 2022
Phase: N/A
Study type: Interventional

in this study the investigators will test anew technique to mange patients with morbid obesity and GERD by doing sleeve gastrectomy plus cruroplasty and omental rape around the gastroesophageal junction

NCT ID: NCT05574049 Completed - Metabolic Syndrome Clinical Trials

Weight Loss, Blood Sugar and Blood Lipid Effects of Tetrahydrocannabivarin (THCV) Impregnated Mucoadhesive Strips

THCV
Start date: January 4, 2022
Phase: Early Phase 1
Study type: Interventional

The goal of this clinical trial is to compare the efficacy of two different daily doses of tetrahydrocannabivarin impregnated mouth strips in healthy non-diabetic obese adults. The main questions to answer are: - Is the low dose treatment superior to placebo for losing weight, abdominal girth, cholesterol levels and blood glucose levels? - Is the low dose treatment superior to placebo for losing weight, abdominal girth, cholesterol levels and blood glucose levels? - Is one dose better than the other dose? Participants will take either the low dose, high dose or placebo dose daily for ninety days and have physical measurements and blood tests obtained at the beginning and the end of the study.