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Neuropathic Pain clinical trials

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NCT ID: NCT00599768 Completed - Neuropathic Pain Clinical Trials

Development and Validation for Taiwan Version ID Pain Questionnaire (ID Pain-T) and DN4 Questionnaire.

Start date: March 2008
Phase:
Study type: Observational

This prospective cohort and multi-site study aims to develop Taiwan version (ID Pain-T) based on the original versions of ID Pain and also DN4, and validate both ID Pain-T and DN4 applied in Taiwanese subjects at the clinical setting.

NCT ID: NCT00576108 Completed - Neuropathic Pain Clinical Trials

A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)

Start date: November 2007
Phase: Phase 2
Study type: Interventional

This study will evaluate the safety and efficacy of 2 weeks of topical KD7040 versus placebo in the treatment of postherpetic neuralgia.

NCT ID: NCT00523016 Completed - Neuropathic Pain Clinical Trials

Acupuncture Treatment to Reduce Burning Pain in Spinal Cord Injury

APSCI
Start date: September 2007
Phase: N/A
Study type: Interventional

Acupuncture has been used with good results for many years at Toronto Rehabilitation Institute Lyndhurst Centre (Toronto, ON, Canada), Parkwood Hospital (London, ON, Canada) and GF Strong Rehabilitation Institute (Vancouver, BC, Canada) to reduce burning pain in individuals with spinal cord injuries (SCI). This multi-centre RCT will test an acupuncture protocol for treatment of burning pain in 40 people with burning pain in SCI, using a sham acupuncture protocol as the control. Objectives of Study: 1. To determine the feasibility of conducting a real acupuncture vs. sham acupuncture trial in a multi-centre study using the Lyndhurst Central Neuropathic Pain Acupuncture Protocol (LCCNPAP). This will inform a larger study which will directly evaluate the effect of the LCCNPAP on pain and Quality of Life (QOL) in individuals with SCI. 2. To determine which outcome measures are most responsive and the amount of change that could be expected, with respect to pain and QOL, for the larger study. 3. To obtain preliminary data to determine subject numbers for future studies evaluating the effect of the acupuncture protocol.

NCT ID: NCT00480181 Completed - Multiple Sclerosis Clinical Trials

Efficacy and Safety Evaluation of Nabilone as Adjunctive Therapy to Gabapentin for the Management of Neuropathic Pain in Multiple Sclerosis

Start date: June 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether nabilone (Cesamet) when used as an adjunctive agent with gabapentin (Neurontin) provides significantly improved pain relief over gabapentin alone for the management of neuropathic pain in MS.

NCT ID: NCT00474916 Completed - Neuropathic Pain Clinical Trials

Neuropathic Pain in Patients With Cancer

Start date: June 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to collect beginning information on whether intravenous (IV) administration of KRN5500 is safe and effective for treatment of neuropathic pain in patients with cancer.

NCT ID: NCT00462566 Completed - Neuropathic Pain Clinical Trials

The Efficacy of Motor Cortex Stimulation for Pain Control

Start date: October 2005
Phase: N/A
Study type: Interventional

The objective is to determine if motor cortex stimulation works for the following conditions: 1. Deafferentation facial pain, 2. Upper extremity complex regional pain syndrome (CRPS) and 3. Brachial plexus avulsion or phantom limb pain. Each of these groups of 6 patients (total of 18) will be studied independently and all patients will be implanted with a motor cortex stimulation system. They will be randomised to either a regular or low stimulation setting in the two arms of the study. Each arm will last 3 months.

NCT ID: NCT00443469 Completed - Neuropathic Pain Clinical Trials

Spinal Magnetic Stimulation in Neuropathic Pain

Start date: August 2006
Phase: Phase 3
Study type: Interventional

It involves delivering a train of magnetic pulses, 5 at each time, to the brain. In the present study, we are using the same method to treat severe pain due to nerve conditions. You will be given up to 1000 pulses in total over the spine in the lower back (Spinal Magnetic Stimulation or SMS). Each train will be given in 10-second intervals. You will have SMS on a single day. You will be given SMS pulses at 1 or 10 per second. No stimulation will be given over the head. You will be assessed before and after the study for up to 1 week. Your usual medical treatment will be continued

NCT ID: NCT00414349 Completed - Neuropathic Pain Clinical Trials

Efficacy and Safety of Topical Versus Systemic Treatment in Postherpetic Neuralgia and Diabetic Polyneuropathic Pain

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate lidocaine as topical treatment for peripheral neuropathic pain (as stand-alone treatment and in combination with systemic treatment)

NCT ID: NCT00376454 Completed - Neuropathic Pain Clinical Trials

The Study of GW493838, an Adenosine A1 Agonist, in Peripheral Neuropathic Pain

Start date: November 2002
Phase: Phase 2
Study type: Interventional

The purpose of this study was to determine the analgesic effect of GW493838 in patients with post-herpetic neuralgia or peripheral nerve injury caused by trauma or surgery.

NCT ID: NCT00336349 Completed - Diabetes Mellitus Clinical Trials

A Study of Intra-dermal Injection of Botulinum Toxin Type A for the Diabetic Neuropathic Foot Pain

Start date: June 2006
Phase: N/A
Study type: Interventional

Effective treatment of neuropathic foot pain in diabetic patients is very important to improve their quality of life. There are many medications used to reduce the diabetic neuropathic pain, including anticonvulsants, anti-depressants or analgesics, but none is universally satisfied. A few previous studies employing BOTOX® i.d. injection for control of trigeminal neuralgia, post-herpes neuralgia indicate that BOTOX® was effective in controlling neuropathic pain. Intradermal injection of BOTOX® to the dorsum of the foot in diabetics should be effective in controlling diabetes-associated polyneuropathic pain of the foot.