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Nausea clinical trials

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NCT ID: NCT06357234 Not yet recruiting - Anesthesia Clinical Trials

Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This research trial will measure how useful Aprepitant is in preventing nausea and vomiting in children having surgery to correct scoliosis (curvature of the spine).

NCT ID: NCT06356623 Not yet recruiting - Liver Cancer Clinical Trials

A Risk Prediction Model of Postoperative Nausea and Vomiting in Patients With Liver Cancer

Start date: May 5, 2024
Phase:
Study type: Observational

PONV management has been recommended as a necessary part of enhanced recovery protocols during the perioperative period, and PONV risk assessment is, therefore, a necessary first step in determining the number of medications or strategies for prophylaxis and treatment by considering the number of modifiable and non-modifiable risk factors. However, the external validity of two commonly-used PONV prediction models for patients undergoing liver surgery is unsatisfied, and need to be updated for liver cancer populations to better inform personalized perioperative care regime and individualized decision-making in clinical practice.

NCT ID: NCT06342778 Completed - Nausea Clinical Trials

Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin

Start date: February 27, 2024
Phase: Phase 1
Study type: Interventional

Comparative study of pharmacokinetics and bioequivalence of the study drug Doxylamine + Pyridoxine, enteric-soluble, film-coated tablets, 10 mg + 10 mg (Valenta Pharm JSC, Russia), and reference drug Diclectin, delayed-release tablets, 10 mg + 10 mg (registration certificate holder - Tzamal Bio-Pharma, Israel, manufacturer - Duchesnay Inc, Canada) in healthy volunteers after meals

NCT ID: NCT06333626 Not yet recruiting - Clinical trials for Nausea and Vomiting, Aspiration, Intraoperative

Effects of an Oral Multi-vitamin Carbohydrate Beverage on Intraoperative Nausea and Vomiting

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Nausea and vomiting are common and unpleasant symptoms for pregnant women during cesarean section, which can lead to aspiration, a serious complication that can cause pneumonia. Our study aimed to evaluate the effects of oral multi-vitamin carbohydrate beverage on maternal intraoperative nausea and vomiting by gastric ultrasound.

NCT ID: NCT06331520 Not yet recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

NEPA Combined With Olanzapine, Dexamethasone-sparing for the Effect of CINV in Patients Receiving HEC Regimens

Start date: May 1, 2024
Phase: Phase 3
Study type: Interventional

The objective of this Prospective, randomized, non inferiority phase III trial is to confirm the efficacy and saftey of dexamethasone-sparing combined with netupitant/palonostron and olanzapine for the prevention of chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy.

NCT ID: NCT06316648 Completed - Clinical trials for Elective Hip Fracture Surgery

Whey Intake Blood Glucose, Fasting, Thirst, Nausea and Vomiting Levels of Patients Undergoing Elective Hip Fracture Surgery

Start date: April 20, 2021
Phase: N/A
Study type: Interventional

Whey Intake Blood Glucose, Fasting, Thirst, Nausea, Vomiting Elective Hip Fracture Surgery

NCT ID: NCT06314906 Recruiting - Nausea and Vomiting Clinical Trials

Electroacupuncture Plus Antiemetic Therapy for Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer

Start date: March 7, 2024
Phase: Phase 3
Study type: Interventional

This study explores the effectiveness of combining electroacupuncture with olanzapine-containing four-drug antiemetic therapy to mitigate chemotherapy-induced nausea and vomiting (CINV) in patients with breast cancer. The research aims to assess the adjunctive benefits of electroacupuncture in enhancing the antiemetic effects of conventional medication, particularly in the context of highly emetogenic chemotherapy regimens. By investigating the synergistic potential of these modalities, the study seeks to provide insights into optimizing supportive care strategies for patients with breast cancer undergoing intensive chemotherapy treatment.

NCT ID: NCT06302673 Recruiting - Clinical trials for Nausea and Vomiting, Postoperative

The Role Of Laserpuncture For Prevention Of Nausea And Vomiting Post Strabismus Surgery With General Anesthesia In Adult Patients

Start date: October 9, 2023
Phase: N/A
Study type: Interventional

This study to determine the effectiveness of a combination of pre-surgical laserpuncture with standard anti-emetic therapy for PONV symptoms in adult patients after strabismus surgery under general anesthesia compared to a combination of pre-surgical placebo laserpuncture with standard anti-emetic therapy. Research design using a double blinded randomized controlled trial (RCT) where research subjects and data takers who will be disguised. The research will be carried out in the Operation and Inpatient Room, Kirana Building, RSUPN Dr. Cipto Mangunkusumo (RSCM) with research subjects as adult patients undergoing strabismus surgery under general anesthesia. Assessment of nausea and vomiting using AVS ( Analog Visual Scale) consists of scoring using a score from 1-5 which indicates the severity of nausea and vomiting.

NCT ID: NCT06288542 Not yet recruiting - Clinical trials for Effect of Dextrose on Postoperative Nausea and Vomiting

Preoperative Dextrose Infusion and Postoperative Nausea and Vomiting

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

This research aims to investigate the efficacy of preoperative intravenous infusion of dextrose 5% during fasting in lowering the incidence and severity of post-operative nausea and vomiting related to laparoscopic gynaecologic procedures

NCT ID: NCT06288035 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Oral Dexamethasone for Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Start date: March 4, 2024
Phase: Phase 3
Study type: Interventional

Postoperative nausea and vomiting (PONV) are common complications after laparoscopic cholecystectomy. This study aims to evaluate the efficacy of the administration of prophylactic oral dexamethasone at night before surgery in preventing PONV after elective laparoscopic cholecystectomy.