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Clinical Trial Summary

This study will test the safety of a drug called SGN-PDL1V alone and with pembrolizumab in participants with solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to your body besides treating your disease. Participants will have solid tumor cancer that has spread through the body (metastatic) or cannot be removed with surgery (unresectable). This study will have four parts. Parts A and B of the study will find out how much SGN- PDL1V should be given to participants. Part C will use the dose found in Parts A and B to find out how safe SGN-PDL1V is and if it works to treat solid tumor cancers. In Part D, participants will be given SGN-PDL1V with pembrolizumab to find out how safe this combination is and if it works to treat solid tumor cancers.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05208762
Study type Interventional
Source Seagen Inc.
Contact Seagen Trial Information Support
Phone 866-333-7436
Email clinicaltrials@seagen.com
Status Recruiting
Phase Phase 1
Start date October 25, 2022
Completion date December 31, 2026

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