Application of the Web-based Acceptance and Commitment Therapy for Depression

Major Depressive Disorder Clinical Trial

— ACTION  

Official title:

The Efficacy and Treatment Mechanisms of the Web-based Acceptance and Commitment Therapy for Patients With Major Depressive Disorder

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06293781
• Other study ID #: GachonU
• Status: Recruiting
• Phase: N/A
• Start date: December 19, 2022
• Est. completion date: February 28, 2025

Study information

• Verified date: February 2024
• Source: Gachon University
• Contact: Kyoung-Sae Na, MD, PhD
• Phone: 82324689932
• Email: ksna13[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

PROSPECTIVE INTERVENTION STUDY; EFFICACY OF WEB-BASED ACCEPTANCE AND COMMITMENT THERAPY

Description:

Acceptance Commitment Therapy (ACT) is known to help people recover from depression by improving psychological flexibility through acceptance, defusion, self-as-context, present moment, committed action, and helping them live a values-based life. This study is a randomized controlled trial to determine if web-based ACT leads to changes in the psychological flexibility and cognitive fusion. Also, through the functional MRI study, possible treatment mechanisms by which the web-based ACT exerts will be identified.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: February 28, 2025
• Est. primary completion date: February 28, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 19 Years to 65 Years

Eligibility

Inclusion Criteria:

• Patients who diagnosed major depressive disorder

Exclusion Criteria:

• Patients who have serious medical problems, metal implants in their bodies, severe brain injury or brain disease

• Women who were pregnant or nursing

• Patients at high risk for suicide

Related Conditions & MeSH terms

• Depression
• Depressive Disorder
• Depressive Disorder, Major
• Major Depressive Disorder

Intervention

Device:
• Web-based ACT
ACT program delivered online

Behavioral:
• Treatment as usual
Treatment as usual for major depressive disorder

Locations

Country	Name	City	State
Korea, Republic of	Kyoung-Sae Na	Incheon	Please Incheon

Sponsors (1)

Lead Sponsor	Collaborator
Gachon University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Acceptance and Action Questionnaire-II	Psychological flexibility	6 weeks
Secondary	Cognitive Fusion Questionnaire	Cognitive fusion	6 weeks