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Psilocybin in Co-occuring Major Depressive Disorder and Borderline Personality Disorder

Major Depressive Disorder Clinical Trial

Official title:
An Open Label Study of Single-Dose Psilocybin for Major Depressive Disorder With Co-occurring Borderline Personality Disorder

Clinical Trial Summary

The primary objective of the study is to evaluate the safety and efficacy of psilocybin in adults with major depressive disorder (MDD) and borderline personality disorder (BPD).

Clinical Trial Description

The primary objective of the proposed study is to evaluate the safety and efficacy of psilocybin in adults with major depressive disorder (MDD) and borderline personality disorder (BPD). Ten subjects with MDD and BPD will receive a single 25 mg oral dose of psilocybin. The hypothesis to be tested is that psilocybin will result significant reduction in symptoms of both MDD and BPD after 1 week and sustained for 4 weeks compared to baseline (improvement in symptoms will be indicated by lower scores on established outcome measures of MDD and BPD symptoms that have been used in prior studies). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05399498
Study type Interventional
Source University of Chicago
Contact Madison Collins, BA
Phone 773-834-3778
Email mcollins4@bsd.uchicago.edu
Status Recruiting
Phase Phase 2
Start date November 1, 2023
Completion date August 2024
View Details
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