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Safety and Tolerability of Single and Multiple Ascending Doses of GATE-101 in Normal Human Volunteers

Major Depressive Disorder Clinical Trial

Official title:
A Randomized Double-blind, Placebo-controlled Single and Multiple Intravenous Ascending Dose Study of the Safety, Tolerability and Pharmacokinetics of GATE-101 in Normal Healthy Volunteers

Clinical Trial Summary

To evaluate the safety, tolerability, and pharmacokinetics of single and multiple ascending doses of GATE-101 in normal human volunteers

Clinical Trial Description

Single ascending dose (SAD), multiple ascending dose (MAD), double-blind placebo-controlled study in normal human volunteers. Secondary objectives: To evaluate the pharmacokinetics (PK) of GATE-101 following increasing single and multiple doses of intravenously (IV) administered GATE-101. GATE-101 or Placebo: Dose/Mode of Administration: Single or 5 Daily Doses;Intravenous ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04618263
Study type Interventional
Source Gate Neurosciences, Inc
Contact
Status Terminated
Phase Phase 1
Start date October 26, 2020
Completion date August 13, 2021
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