Major Depressive Disorder Clinical Trial
Official title:
How Can Change of Dysfunctional Expectations in Major Depression be Enhanced? An Experimental Study Targeting Cognitive Immunization
Verified date | August 2018 |
Source | Philipps University Marburg Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Research has shown that people suffering from MDD tend to maintain dysfunctional expectations despite experiences that disconfirm expectations. Recently, it has been shown that this persistence of expectations is due to maladaptive information processing involving "cognitive immunization". This experimental study aims at testing three different strategies to inhibit cognitive immunization, in order to enhance expectation change.
Status | Completed |
Enrollment | 135 |
Est. completion date | August 21, 2018 |
Est. primary completion date | April 30, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - current diagnosis of Major Depressive Disorder - at least 18 years old - sufficient German language knowledge Exclusion Criteria: - none |
Country | Name | City | State |
---|---|---|---|
Germany | Schoen Klinik Bad Arolsen | Bad Arolsen | Hessen |
Lead Sponsor | Collaborator |
---|---|
Philipps University Marburg Medical Center |
Germany,
Kube T, Rief W, Gollwitzer M, Glombiewski JA. Introducing an EXperimental Paradigm to investigate Expectation Change (EXPEC). J Behav Ther Exp Psychiatry. 2018 Jun;59:92-99. doi: 10.1016/j.jbtep.2017.12.002. Epub 2017 Dec 12. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Performance Expectations Scale - generalized | Change from Baseline to Postassessment in generalized performance expectations | Directly prior to the performance test and directly after completing the performance test | |
Secondary | Performance Expectations Scale - task-specific | Change from Baseline to Postassessment in task-specific performance expectations | Directly prior to the performance test and directly after completing the performance test |
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