Brain Mechanisms of Human Motivation

Major Depressive Disorder Clinical Trial

Official title: Multi Level Analysis of Positive Valence Systems Across Mood Disorders

Status Completed

Clinical Trial Summary

This study aims to investigate reward learning across the mood disorder spectrum and to investigate the predictive validity of reward learning for subsequent symptom severity.

Clinical Trial Description

The study involves five sessions. In the first session, participants will play a computer task. In the second session, participants will go through a clinical interview and will have an EEG recording while playing another computer task. In the third session, participants will undergo an fMRI scan while playing another computer task. All tasks assess reward learning. At three and six months after the final session, participants will come back for a follow-up interview session during which a clinician will assess symptom severity. There will be no intervention in this study. ;

Related Conditions & MeSH terms

• Bipolar Disorder
• Depression
• Depressive Disorder
• Depressive Disorder, Major
• Disease
• Major Depressive Disorder

• NCT number: NCT01976975
• Study type: Observational
• Source: Mclean Hospital
• Status: Completed
• Start date: October 2013
• Completion date: January 2018