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Repetitive Transcranial Magnetic Stimulation(rTMS) in the Treatment of Depression

Major Depressive Disorder Clinical Trial

Official title:
Repetitive Transcranial Magnetic Stimulation(rTMS) in the Treatment of Depression : Effect of TMS on Depression, Cognitive Function, and Regional Cerebral Glucose Metabolism

Clinical Trial Summary

The objective of this study is to investigate the antidepressant efficacy of rTMS, and to assess cortical metabolism before and after rTMS sessions in patients with major depression. We also aimed to investigate differences between the responders and nonresponders to rTMS and what would predict clinical response to rTMS.

Clinical Trial Description

The specific aims of this study is to: (1) evaluate the antidepressant efficacy of rTMS on major depression; (2) evaluate the effects of rTMS on cognitive function in depressive patients; (3) assess the effects of rTMS on cerebral glucose metabolism in depressive patients as measured by 18FDG PET; (4) investigate the differences of the regional cerebral glucose uptake changes during rTMS between responders and nonresponders to rTMS. ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01198561
Study type Observational
Source Samsung Medical Center
Contact Doh Kwan Kim, M.D., Ph.D.
Phone 82-2-3410-3582
Email paulkim@skku.edu
Status Recruiting
Phase N/A
Start date February 2006
Completion date December 2016
View Details
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