Slow-wave Sleep Deprivation in Depression

Status Completed

Clinical Trial Summary

Sleep deprivation can acutely reverse depressive symptoms in patients with major depression. Although underlying mechanisms of the antidepressant action in sleep deprivation are unclear, many of these observations can be explained by abnormal slow wave homeostasis. This study will test the prediction that selectively reducing slow waves during sleep (slow wave deprivation; SWD), without disrupting total sleep time, will yield an antidepressant effect.

Clinical Trial Description

see above ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01189591
Study type	Interventional
Source	University of Wisconsin, Madison
Contact
Status	Completed
Phase	N/A
Start date	June 2009
Completion date	August 2011

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