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Clinical Trial Summary

Sleep deprivation can acutely reverse depressive symptoms in patients with major depression. Although underlying mechanisms of the antidepressant action in sleep deprivation are unclear, many of these observations can be explained by abnormal slow wave homeostasis. This study will test the prediction that selectively reducing slow waves during sleep (slow wave deprivation; SWD), without disrupting total sleep time, will yield an antidepressant effect.


Clinical Trial Description

see above ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01189591
Study type Interventional
Source University of Wisconsin, Madison
Contact
Status Completed
Phase N/A
Start date June 2009
Completion date August 2011

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