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Clinical Trial Summary

The knowledge of the pathogenesis of retinal affections, a major cause of blindness, has greatly benefited from recent advances in retinal imaging. However, optical aberrations of the ocular media limit the resolution that can be achieved by current techniques. The use of an adaptive optics system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many retinal microstructures: photoreceptors, vessels, bundles of nerve fibers. Recently, the development of the coupling of the two main imaging techniques, the Adaptive Optics Ophthalmoscope with Optical Coherence Tomography, enables unparalleled three-dimensional in vivo cell-scale imaging, while remaining comfortable for the patients. The purpose of this project is to evaluate the performance of this system for imaging micrometric retinal structures.


Clinical Trial Description

The goal of the project is the capture and analysis of images with AOSLO system, in order to evaluate the performance of this system compared to OCT imaging devices and existing Adaptive Optics used at National Hospital of Ophthalmology. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04620876
Study type Interventional
Source Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Contact Hayet Serhane
Phone 0140021144
Email hserhane@15-20.fr
Status Recruiting
Phase N/A
Start date October 1, 2019
Completion date October 15, 2024

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