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Lacerations clinical trials

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NCT ID: NCT02882256 Completed - Clinical trials for Urinary Tract Infection

Video Discharge Instructions (VDI) as Adjuncts to Written Discharge Instructions in the Emergency Department

Start date: June 2016
Phase: N/A
Study type: Interventional

Patients seen in the ED with either a laceration, minor head injury, or urinary tract infection will be randomized to one of two groups. Both groups will receive the standard written discharge instructions; in addition, one group will watch video discharge instructions. Each patient will be asked to complete a short survey with questions related to the discharge instructions received in the ED, and will be called 5-7 days after the ED visit to ask questions about discharge instructions and the ED visit.

NCT ID: NCT02618772 Completed - Anxiety Clinical Trials

Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department

Start date: January 2010
Phase: Phase 4
Study type: Interventional

Laceration repair can cause significant anxiety in children. As open wounds account for 21-25% of injuries in children presenting to the emergency department, the management of anxiety is of great importance. Anxiety can often lead to poor patient cooperation and the use of potentially excessive physical restraint. High rates of procedural anxiety have also been correlated with increased rates of negative behaviours after discharge. The current standard of care for suture closure of lacerations throughout most of Canada is to provide local analgesia only. The literature has therefore focused on finding anxiolytic adjuncts to local analgesia. Midazolam is an ideal adjunct due to its fast onset and short duration of action with an excellent safety profile. The advantages of the IN route are less pain on administration when compared to the IV and IM routes, and increased acceptability compared to the rectal route in older children. Oral midazolam also has poor palatability. While the onset of INM at 5-10 minutes, and duration of 20-40 minutes make it an ideal candidate for anxiolysis in the ED its use has been limited by the common side effect of nasal irritation, burning and lacrimation when it is administered in its droplet form. The recent development of mucosal atomization devices (MAD) has resolved this issue by delivering 30-μ particles to the nasal mucosa. Previous studies investigating the use of INM for laceration repair in the pediatric ED have demonstrated that INM is safe but most used non-validated measurement tools to assess anxiety and facilitation. Only one of these studies used atomized INM, retrospectively examining safety as the primary outcome. The authors reported an excellent safety profile for INM using the mucosal atomization device MAD-300 (Wolfe Tory Medical Inc.). The use of atomized INM for anxiolysis during pediatric laceration repair has not been evaluated prospectively. Most studies have focused on preschool aged children (<6 years). While studies have demonstrated that the prevalence of procedural anxiety is higher in younger children, up to 51% of children age 7-12 years experience high levels of procedural distress. The effectiveness of INM in the pre-adolescent age group is, therefore, yet to be determined. It is hypothesized that INM will reduce anxiety in children age 2-12 years undergoing laceration repair and will facilitate the successful completion of suturing by the physician.

NCT ID: NCT02333877 Completed - Wounds and Injuries Clinical Trials

Comparison of Skinlink With Suture for ED Patients

Skinlink
Start date: January 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether suture using the Device of "Leukosan Skinlink" is more faster and safer than that of "nylon" in the treatment of simple wound for ED patients.

NCT ID: NCT02237001 Completed - Meniscus Tear Clinical Trials

Study of Suture Repair of Torn Meniscus in the Knee

STITCH
Start date: November 19, 2014
Phase: N/A
Study type: Interventional

Horizontal meniscus tears meeting specified criteria will be repaired by any commonly used suture technique. Subjects will be followed for 2 years to evaluate the effectiveness of the repair, by assessing the re-operation rate, and by assessing improvements in knee pain and knee function.

NCT ID: NCT02217436 Completed - Anxiety Clinical Trials

iPad as a Distraction Tool During Facial Laceration Repair

Start date: April 2014
Phase: N/A
Study type: Interventional

Children aged 2-12 presenting to the Rady Children's Hospital San Diego (RCHSD) emergency department with facial lacerations requiring suture repair will be eligible to participate in the study. Participating children will be randomized to standard care versus standard care plus iPad use during the procedure. Children's anxiety levels assessed using a validated scale will be measured from video recordings made of the procedure. Parent and provider satisfaction surveys will be completed following the procedure. The primary study aim is to determine how iPad use affects children's anxiety levels during facial laceration repair. The secondary study aim is to determine how iPad use affects parent and provider satisfaction regarding a child's facial laceration repair. Hypothesis is that iPad use decreases children's anxiety levels during facial laceration repair and increases parent and provider satisfaction regarding a child's facial laceration repair.

NCT ID: NCT02159911 Completed - Adverse Effects Clinical Trials

Oral Misoprostol for Cervical Priming Before Hysteroscopy

Start date: June 2004
Phase: N/A
Study type: Observational

A randomized, double blind study to compare 200 and 400 mcg misoprostol for cervical preparation before hysteroscopy.

NCT ID: NCT02055794 Completed - Neuralgia, Perineal Clinical Trials

Promoting Optimal Healing After Laceration Repair Study

PALS
Start date: February 2014
Phase: N/A
Study type: Interventional

The goal of this research is to investigate three different methods of perineal skin closure during second-degree perineal wound repair and determine which method is associated with the least amount of patient pain. Null hypothesis: There will be no difference in patient pain among the three different methods for second degree perineal wound repair.

NCT ID: NCT01948908 Completed - Clinical trials for Children Requiring Sedation to Facilitate Laceration Repair

Volumes of Administration for Intranasal Midazolam

Start date: June 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine exactly how much drug volume should be administered into each nare, so that the drug absorption can be maximized and the amount that runs out of the nose, or is swallowed, is minimized, thereby optimizing the effectiveness of any drug given intranasally. The investigators will determine this ideal "volume of administration" by studying intranasal midazolam in children who require sedation to facilitate laceration repairs. The investigators will evaluate both clinical outcomes as well as pharmacokinetic outcomes associated with each volume of administration. We will block randomize children to receive intranasal midazolam in maximum aliquots of one of the three following VOA: 200 microliters (mcL), 500 mcL, or 1000 mcL.

NCT ID: NCT01899781 Completed - Hand Laceration Clinical Trials

Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon

Start date: August 2013
Phase: Phase 4
Study type: Interventional

The investigators assume that simple hand lacerations involving flexors or extensors tendons, do not require prophylactic antibiotic treatment to prevent wound infection.

NCT ID: NCT01716013 Completed - Clinical trials for Traumatic Lacerations or Surgical Incisions

Safety and Efficacy Study of BondEase to Treat Traumatic Lacerations and Surgical Incisions

Start date: September 2012
Phase: N/A
Study type: Interventional

To demonstrate that BondEase™ and conventional wound closure devices (CWCD) are the same in terms of cosmesis (appearance) of the repaired wound when these devices are used for closure of surgical and traumatic wounds . To demonstrate safety of BondEase™.