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Labor Pain clinical trials

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NCT ID: NCT03975816 Recruiting - Labor Pain Clinical Trials

The Application of Analgesia Nociception Index as an Objective Labor Pain Assessment During Epidural Analgesia

Start date: November 17, 2019
Phase:
Study type: Observational

Epidural analgesia is considered an effective and safe method for obstetric pain control. Currently, self-assessment pain scales remain to be the gold standard in labor pain evaluation after the administration of epidural analgesia. However, individual patient susceptibility to pain perception makes difficulties for the clinicians to assess the effectiveness of painless labor precisely. The aim of this study is to evaluate the validity of ANI in obstetric pain monitoring during epidural analgesia.

NCT ID: NCT03975660 Recruiting - Pain Clinical Trials

Evaluation of Objective Pain Measurement Device

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

This study will attempt to objectively measure pain with an experimental device. The investigators will apply the device to measure patients "pain" due to uterine contractions during routine clinical care to correlate patients verbal pain ratings and analgesia requirements to that measured by the device. A brain oxygenation device, Edwards Foresight, will be used to concurrently to monitor brain oxygenation and hemodynamics, so the relationship between the CereVu ROPA device objective measure of pain and brain oxygenation/hemodynamic changes and patient-reported pain can be determined.

NCT ID: NCT03829592 Recruiting - Labor Pain Clinical Trials

TheEffect of pH on Misoprostol in Induction of Labor

Start date: February 6, 2019
Phase: N/A
Study type: Interventional

Misoprostol is a synthetic analogue of the naturally occurring prostaglandin E1. It was initially marketed for the treatment of peptic ulcers due to its mucosal protective and anti-secretory properties, but has commonly been used for the induction of abortion and labour .

NCT ID: NCT03730753 Recruiting - Labor Pain Clinical Trials

Programmed Intermittent Epidural Bolus Versus Continuous Infusion in Labour Analgesia

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

This study aims to establish if programmed intermittent epidural bolus combined to patient controlled analgesia in labour analgesia will lower the hourly bupivacaine consumption when compared to continuous infusion combined with patient controlled analgesia. The investigators' hypothesis is that the use of programmed intermittent epidural bolus will lower the hourly bupivacaine consumption.

NCT ID: NCT03623256 Recruiting - Labor Pain Clinical Trials

Comparison of Intrathecal Versus Epidural Fentanyl on Fetal Bradycardia in Labor Combined Spinal Epidural Analgesia

Start date: October 28, 2019
Phase: Phase 4
Study type: Interventional

There have been studies reporting that combined spinal-epidural (CSE) with fentanyl and bupivacaine produce fetal bradycardia, (M.Kuczkowski, 2004) (Abrão K, 2009 ). It is unknown whether any differences in risk exist between fentanyl and bupivacaine when used as a part of the CSE procedure. Some authors have reported cases of parturients who developed uterine hyperactivity and fetal bradycardia after subarachnoid administration of fentanyl during labor. (D'Angelo & Eisenach, 1997) (Friedlander JD, 1997). It has been suggested that uterine hypertonus, leading to non-reassuring fetal heart rate tracings, might be an etiologic factor in these situations. (Landau, 2002). We propose this study to test the hypothesis that administration of epidural fentanyl is associated with a lower incidence of fetal bradycardia compared to intrathecal fentanyl.

NCT ID: NCT03496857 Recruiting - Labor Pain Clinical Trials

Effect of LED Photobiomodulation on Analgesia During Labor

EPAL
Start date: March 28, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to valuate the effects of LED photobiomodulation on analgesia during labor.ight-emitting diode (LED) photobiomodulation is an effective and noninvasive alternative to pharmacological methods.n total, 60 women in labor admitted to a public maternity hospital will be selected for a randomized controlled trial. The participants will be randomized into two groups: intervention group [analgesia with LED therapy (n = 30)] and control group [analgesia with bath therapy (n = 30)].

NCT ID: NCT03381495 Recruiting - Labor Pain Clinical Trials

The Association Between Epidural Labor Analgesia and Pregnancy Outcomes

Start date: May 16, 2018
Phase: N/A
Study type: Interventional

Labor analgesia can alleviate intrapartum pain, in the importance of the delivery is very obvious.But some researches think labor analgesia may affect the progress of labor, increase the cesarean section rate.This research adopts the epidural anesthesia to study labor analgesia effects on delivery outcomes and long-term emotional and psychological effects on the mothers. Besides, we also want to study the effect of exercise during pregnancy on the mode of delivery.

NCT ID: NCT03344042 Recruiting - Labor Pain Clinical Trials

Effect of Epidural Opioid Administered in the First A Period on the Progress of Labour

Start date: December 1, 2017
Phase: Phase 4
Study type: Interventional

Epidural anesthesia is used to relieve labour pain which helps reduce labour stress, increase comfort and improve cooperation with medical personnel. Administering opioid into the epidural space before cervical dilation of 4cm in the primigravida or 3cm in the multiparous can effectively reduce the pain levels with no effect on the labour progress. The aim of the study is to compare different opioids administered in this early labour stage.

NCT ID: NCT03120780 Recruiting - Labor Pain Clinical Trials

Epidural Fentanyl for 2nd Stage Labor Analgesia

Start date: June 26, 2017
Phase: Phase 4
Study type: Interventional

This study is being done to investigate if there is more effective pain relief during the latter stages of labor and delivery when epidural fentanyl 100mcg is administered compared to epidural fentanyl 20mcg.

NCT ID: NCT03018171 Recruiting - Labor Pain Clinical Trials

Intrathecal Clonidine Addiction for Combined Spinal Epidural Analgesia During Labor

ICA
Start date: January 2017
Phase: Phase 4
Study type: Interventional

The study aims to evaluate the impact of the addition of 20 mcg of intrathecal clonidine in combined spinalepidural for labor analgesia on the local anesthetic consumption, on labor performance and on maternal fetal well-being.