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Labor Pain clinical trials

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NCT ID: NCT04964206 Recruiting - Labor Pain Clinical Trials

Neuraxial Labor Analgesia and Offspring Neurodevelopment

Start date: October 14, 2022
Phase:
Study type: Observational [Patient Registry]

How perinatal factors affect the long-term development of children has always been an issue of much concern. This study is designed to explore the potential impact of maternal neuraxial labor analgesia exposure on offspring neurodevelopment.

NCT ID: NCT04946032 Recruiting - Labor Pain Clinical Trials

Optimum Length of Catheter in the Epidural Space for Labor Analgesia in Non-obese Women: a Randomised Controlled Trial of 4 cm Versus 5 cm

Start date: November 23, 2021
Phase: N/A
Study type: Interventional

Epidural analgesia was introduced to the world of obstetrics in 1909 by Walter Stoeckel. Over the following 100 years it has developed to become the gold-standard for delivery of intra-partum analgesia, with between 60 and 75% of North American parturients receiving an epidural during their labor. Effective labor analgesia has been shown to improve maternal and fetal outcomes. One aspect of catheter insertion that has not been fully evaluated, and with very little recent work undertaken, is the optimal length of epidural catheter to be left in the epidural space. Dislodgement or displacement of epidural catheter remains a significant cause for failure with analgesia. Novel methods of fixation may further reduce the risk of catheter migration. Another factor is the direction of travel within the epidural space, only 13% of lumbar catheters remain uncoiled after insertion of more than 4 cm into the epidural space. Hypothesis: The investigators hypothesize that catheters inserted to 4 cm will have a lower rate of failure when compared to those inserted to 5 cm. Objective: This study aims to evaluate the difference in quality of labor analgesia delivered by epidural catheters inserted to either 4 or 5 cm into the epidural space. This study will be conducted as an interventional double-blinded randomised control trial to establish best practice.

NCT ID: NCT04728048 Recruiting - Anesthesia Clinical Trials

Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia

DPE
Start date: January 19, 2021
Phase: N/A
Study type: Interventional

The purpose of this prospective randomized controlled study is to compare the number of physician top-up interventions during the first stage of labour between two different neuraxial analgesia techniques : the dural puncture epidural and the standard epidural.

NCT ID: NCT04662424 Recruiting - Labor Pain Clinical Trials

Effect of Music in Labor in Women Who Underwent Induction of Labor

Start date: December 3, 2020
Phase: N/A
Study type: Interventional

Women's experience of pain during labor varies greatly, and pain control is a major concern for obstetricians. Several methods have been studied for pain management for women in labor, including drug and non-drug interventions Most methods of non-pharmacological pain management are non-invasive and appear to be safe for mother and baby, including immersion in water, relaxation, acupuncture, and massage. However, their efficacy is unclear, and based mostly on non-randomized studies. On the other hand, there are strong data to support the efficacy of pharmacological methods, including epidural analgesia, which improves pain relief but increase the incidence of operative vaginal delivery Recently a clinical trial showed that music in labor was associated with maternal benefits in women who underwent spontaneous vaginal delivery. However, the effect of music in labor in women undergoing induction of labor is still a subject of debate.

NCT ID: NCT04469101 Recruiting - Labor Pain Clinical Trials

A Study on the Effect of Position on Walking Labour Epidural Efficacy

Start date: May 31, 2021
Phase: N/A
Study type: Interventional

This study is being done to better understand how patient positioning can affect pain relief after an epidural. In addition to pain, the investigators will assess how position affects epidural spread, and its effects on maternal blood pressure and fetal heart rate.

NCT ID: NCT04290702 Recruiting - Analgesia Clinical Trials

Comparison of Epidural, Combined and Dural Puncture Labor Epidural on Pain, and Course of Vaginal Delivery

Start date: February 26, 2020
Phase: N/A
Study type: Interventional

The three standard techniques used for labor analgesia, thus epidural, combined spinal-epidural and dural puncture epidural will be compared regarding their impact on pain intensity, analgesic and local anesthetic consumption and course of vaginal delivery in a prospective, randomised, double blind manner

NCT ID: NCT04136301 Recruiting - Anxiety Clinical Trials

The Effect of Exposure to an Informative Video on Maternal Anxiety

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

Stress and anxiety during childbirth have negative consequence on both mother and fetus. Previous studies have learned the effect of several intervention to reduce anxiety during labor- such as music and foot reflexology. Nevertheless, data for informative video before labor for reducing stress and anxiety are sparse. The present study aimed to review and determine the effect of informative video on anxiety, pain and outcomes of the labor in primigravida women.

NCT ID: NCT04109365 Recruiting - Anesthesia, Local Clinical Trials

Obstetric Placement Study Using EST

Start date: December 15, 2020
Phase: N/A
Study type: Interventional

Combined spinal-epidural (CSE) is an established technique for providing labour analgesia to obstetric patients which provides rapid onset but unsustained analgesia. The epidural catheter can be used to extend and provide continuous pain relief, however during single-segment needle-through-needle CSE, the catheter is untested. This study aims to confirm placement of epidural catheters of anesthesia through the epidural stimulation test (EST) which was first described by the PI of the study for confirming placement of epidural catheters approximately 20 years ago.

NCT ID: NCT04011150 Recruiting - Labor Pain Clinical Trials

Development of Variable Volume Automated Mandatory Boluses for Patient-controlled Epidural Analgesia During Labour

VVAMB
Start date: August 11, 2020
Phase: Phase 3
Study type: Interventional

A novel epidural delivery regimen was developed: Variable volume automated mandatory bolus (AMB) (VVAMB) will advance individualisation of labour epidural analgesia, by which a larger volume of bolus may contribute to better spread of the local anaesthetics within brief period and thereby reduces the chances of motor blockade that could reduce instrumental deliveries.

NCT ID: NCT03990441 Recruiting - Labor Pain Clinical Trials

Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) Versus Placebo During the First Stage of Labor

Start date: February 11, 2019
Phase: N/A
Study type: Interventional

This study seeks to verify the analgesic efficacy of TENS during the first stage of labor applying TENS parameters that, according to with the evidence, can be effective for this application and discarding the placebo effect according to the methodological recommendations.