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Knee Osteoarthritis clinical trials

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NCT ID: NCT06444945 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

Effects of Mulligan Mobilization With Movement as Compared to Kaltenborn Joint Mobilization in the Management of Knee Osteoarthritis

Start date: June 10, 2024
Phase: N/A
Study type: Interventional

This study is a randomised controlled trial and the purpose of this study is to determine the Effects of Mulligan mobilization with movement as compared to Kaltenborn joint mobilization in the management of knee osteoarthritis." To determine the effects of Mulligan MWM as compared to Kaltenborn joint mobilization in terms of pain, function, range of motion and gait in persons with knee osteoarthritis.

NCT ID: NCT06444932 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

SUPPLEMENTARY EFFECTS OF RESISTANCE TRAINING IN ADDITION TO JOINT MOBILIZATION IN PERSONS WITH KNEE OSTEOARTHRITIS

Start date: June 10, 2024
Phase: N/A
Study type: Interventional

Joint mobilization and resistance exercise training are effective conservative treatment options for the management of osteoarthritis. However, currently no study has highlighted the supplementary effects of resistance training in addition to joint mobilization in people suffering from knee osteoarthritis. The current study is aimed at bridging the gap in literature and providing evidence regarding the additive impact of resistance training to joint mobilization in knee osteoarthritis.

NCT ID: NCT06430918 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

Neuropathic Pain and it's Relation to Sleep Quality in Knee Osteoarthritis

Start date: May 16, 2024
Phase:
Study type: Observational [Patient Registry]

The primary aim is to investigate the frequency and severity of neuropathic pain and its association with night pain in patients with knee osteoarthritis. For this purpose a progressive longitudinal study design was planned. The secondary aim is to investigate the relationship between night pain and neuropathic pain and sleep quality.

NCT ID: NCT06386679 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

Amniotic Fluid Mesenchymal Stem Cells Developed for Chondrogenic Treatment (AFCC) Injection in Elderly Knee Osteoarthritis Patients

Start date: August 17, 2023
Phase: Phase 1
Study type: Interventional

Amniotic fluid mesenchymal stem cells developed for chondrogenic treatment (AFCC) are used to treat elderly patients suffering from knee osteoarthritis (OA). The injection reduces inflammation and promotes the recovery of knee function, leading to an improved quality of life.

NCT ID: NCT06329492 Enrolling by invitation - Osteoarthritis Clinical Trials

Autologous Alpha-2 Macroglobulin Rich Plasma, Safety and Efficacy in Symptomatic Moderate Knee Osteoarthritis

A2MRP
Start date: January 9, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness and safety of autologous alpha-2 macroglobulin rich plasma (A2MRP) injections in the treatment of knee osteoarthritis (OA).

NCT ID: NCT06268925 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

The Feasibility And Efficacy Of A Telerehabilitation Program For People With Knee Osteoarthiritis In Sri Lanka

Start date: February 22, 2024
Phase: N/A
Study type: Interventional

it will be 8 week zoom program of exercises for knee osteo arthritis. participant will be selected according to elegibilty criteria. pre and post measurements will be obtained. then feasibility and efficacy will be assesed.

NCT ID: NCT06211387 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

ADDITIVE BENEFITS OF KALTENBORN SUSTAINED STRETCH JOINT MOBILIZATION WITH RESISTANCE EXERCISE TRAINING IN KNEE OSTEOARTHRITIS

Start date: January 20, 2024
Phase: N/A
Study type: Interventional

to determine the supplementary effects of Kaltenborn sustained stretch mobilization when combined with resistance training in the management of knee osteoarthritis.

NCT ID: NCT06040827 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension

Start date: September 12, 2023
Phase:
Study type: Observational

The objectives of this prospective observational cohort study are to evaluate the safety, reliability, reproducibility, and accuracy of the Canary canturioTM te post-TKA.

NCT ID: NCT05986617 Enrolling by invitation - Obesity Clinical Trials

Wearable Bioimpedance Analyzer for Tracking Body Composition Changes

Start date: July 14, 2023
Phase: N/A
Study type: Interventional

Obesity, namely at body mass index (BMI) levels exceeding 40kg/m2 (class III obesity), is a risk factor for many diseases including osteoarthritis (OA). In arthroplasty, patients in this population frequently present for and are turned away from surgical intervention. Subsequently, efforts are made to decrease BMI through simple weight loss, yet these have been suggested as ineffective and counterproductive. Furthermore, simple weight loss may include muscle mass loss, which is an additional risk factor for surgery. At the University of Iowa Hospitals and Clinics Orthopedics Department, efforts have been made to encourage muscle mass gain and body fat loss over simple weight loss where progress has been tracked through stationary, multi-frequency bioimpedance analysis (BIA). BIA is a readily available technology offered to industry and consumers, and BIA has recently been incorporated into wearable devices. In the UIHC Orthopedics department, a novel clinic aimed at holistically serving the osteoarthritic-class III obese population for controlled and monitored weight loss through BIA. This study, a randomized controlled trial, aims to recruit adult patients with class III obesity presenting to the arthroplasty-obesity clinic. While all patients will receive individual body composition coaching to increase muscle mass and decrease body fat mass, they will be randomized to one of two cohorts: the study group will receive a wearable BIA wristband (InBody BAND 2) and instruction on its use in addition to the standard coaching, and the control group will only receive the standard coaching. This study aims to identify if the use of a wearable BIA wristband aids in the desired body composition changes. In addition, this study aims to quantify the body composition changes exhibited by each cohort. Finally, this study aims to track surgical outcomes for those patients that are indicated for total joint arthroplasty.

NCT ID: NCT05714267 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

Effect of Noise Control During Total Knee Arthroplasty

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Music has emerged as a well-received medical intervention. Patients may be uncomfortable during total joint replacement, which can result in high sedation requirements. These requirements put patients at risk of surgical stress. This study compares the effect of passive noise-cancellation versus active noise cancellation with music on pain, vital signs and anxiety during elective total knee replacement.