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Knee Osteoarthritis clinical trials

View clinical trials related to Knee Osteoarthritis.

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NCT ID: NCT05482672 Withdrawn - Depression Clinical Trials

GetHealthy-OA: A Program to Improve Pain and Function for Patients With Knee Osteoarthritis, Obesity, and Depression

Start date: April 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The investigators have previously identified knee osteoarthritis patients with the combination of depression and an unhealthy weight may be an increased risk of more rapid joint degeneration and worsening pain. The GetHealthy-OA program combines a mind-body program with the oral supplement fisetin to potentially reduce the risk for this population by treating psychosocial, mechanical, and inflammatory mechanisms of knee osteoarthritis. This randomized clinical trial will compare the GetHealthy-OA program to minimally-enhanced usual care plus an oral placebo.

NCT ID: NCT05477745 Not yet recruiting - Knee Osteoarthritis Clinical Trials

The Correlation Between Femoral Component Implanting Flexion Angle and Posterior Condyle Offset in Cruciate Retaining Total Knee Arthroplasty

Start date: July 29, 2022
Phase:
Study type: Observational

The main aim and scope is making measurement and comparison about the femoral component posterior offset under different femoral component implanting flexion angle in cruciate retaining total knee arthroplasty. The results may identify the influence of the flexion component implanting flexion angle on the femoral component posterior offset.

NCT ID: NCT05469776 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Bicruciate-retaining (2C) Total Knee Arthroplasty (TKA) Versus Posterior-stabilized (PS) Total Knee Arthroplasty (TKA)

Start date: November 1, 2011
Phase: N/A
Study type: Interventional

Total knee arthroplasty (TKA) with the sacrifice of the anterior cruciate ligament is the standard treatment for severe knee osteoarthritis. A number of studies on the kinematics of the prosthetic knee tend to show that implants that preserve the cruciate ligaments best reproduce the kinematics of the healthy knee. The goal is to compare the clinical and radiological results in patients undergoing total knee replacement surgery according to the type of prosthesis used. It is anticipated that the bicruciate-retaining prosthesis will result in better function of the operated knee than the posterior-stabilized prosthesis. Method: - Randomized controlled trial - Monocentric - Randomization will be done using sealed envelopes

NCT ID: NCT05467592 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Central Sensitization in Patients Seeking Outpatient Physical Therapy Services

Start date: July 18, 2022
Phase:
Study type: Observational

This is an observational study to examine presence of CS in patients with knee osteoarthritis (OA), chronic LBP (CLBP), and chronic neck pain (CNP) seeking outpatient physical therapy (PT) services. The study will also examine if outcomes differ between patients with CS and patients without CS symptoms with standard PT interventions.

NCT ID: NCT05461638 Withdrawn - Knee Osteoarthritis Clinical Trials

Kinematic Alignment vs Mechanical Alignment for Total Knee Arthroplasty

KA vs MA
Start date: January 5, 2020
Phase: N/A
Study type: Interventional

This is a prospective, randomized, single-blinded, multi-center trial comparing Kinematic Alignment vs Mechanical Alignment in TKA patients using patient reported outcomes, clinical and functional performance tests and radiographic analyses.

NCT ID: NCT05456711 Recruiting - Knee Osteoarthritis Clinical Trials

Femoral Cartilage Thickness in Knee Osteoarthritis

Start date: May 15, 2022
Phase:
Study type: Observational [Patient Registry]

The aim of the study to investigate the relationship between femoral cartilage thickness in Ultrasonographic evaluation and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis

NCT ID: NCT05453123 Recruiting - Knee Osteoarthritis Clinical Trials

The Effect of Motivational Messages by "WhatsApp" on Adherence to Home Exercise Program

Start date: July 2022
Phase: N/A
Study type: Interventional

This study aims to examine the effect of the text message platform (WhatsApp) on the adherence to home exercise programs, pain and physical function among middle age and older adults with knee OA in two public hospitals in Riyadh city, Saudi Arabia

NCT ID: NCT05449613 Recruiting - Knee Osteoarthritis Clinical Trials

Efficacy and Safety Evaluation of Acupoint Application in the Treatment of Knee Osteoarthritis Joint Pain

Start date: October 1, 2021
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy and safety of acupoint application of Traditional Chinese medicine in the treatment of KOA joint pain through a prospective, randomized, double-blind, placebo-controlled clinical study.

NCT ID: NCT05449236 Completed - Knee Osteoarthritis Clinical Trials

A Reliability and Validity Study of Urdu Version of Western Ontario And MacMaster Osteoarthritis Index

Start date: May 30, 2021
Phase:
Study type: Observational

The aim of the study is to translate and culturally adapt Western Ontario And MacMaster Osteoarthritis Index into Urdu language and to investigate its reliability and validity Pakistani population with primary knee osteoarthritis while assessing its correlation with Lequesne Index.

NCT ID: NCT05448742 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Biplanar PSI Slope-reducing MOWHTO With Tibial Tuberosity Serving as Hinge Axis: Cadaveric Study

Start date: June 22, 2022
Phase: N/A
Study type: Interventional

Six cadaveric lower limbs will have PSI slope-reducing MOWHTO performed on and accuraccy of biplanar correction will be assessed.