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Knee Osteoarthritis clinical trials

View clinical trials related to Knee Osteoarthritis.

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NCT ID: NCT05125289 Completed - Knee Osteoarthritis Clinical Trials

Comparison of Soft Tissue Techniques on Hamstring Flexibility Knee Osteoarthritis

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

The aim of this research is to compare the effects of Graston Technique, active release technique and PNF stretching on hamstring flexibility in Patients with Knee Osteoarthritis. Randomized controlled trials done at Riphah International University, Islamabad.. The sample size was 45. The subjects were divided in three groups, 15 subjects in Graston Technique group, 15 subjects in active release technique group and 15 in PNF stretching group. Study duration was of 6 months. Sampling technique applied was non probability purposive sampling technique. Male and female patients greater than 30 years of age, with unilateral or bilateral OA of grade 1 and 2 in Kellegren and Lawrence criteria for knee OA, having UL/BL hamstring tightness, Pain > 3 on NPRS, ROM > 200 from AKE test were included. Tools used in the study are NPRS, AKE test by goniometer, Lower extremity functional index (LEFI) and WOMAC.

NCT ID: NCT05119764 Completed - Knee Osteoarthritis Clinical Trials

Manual Lymphatic Drainage Before and After Total Knee Replacement, a Single-center Observer-blinded Randomized Controlled Trial

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The aim of this observer-blinded randomized controlled trial is the evaluation of the influence of manual lymphatic drainage (MLD) on the outcome of patients receiving total knee replacement (TKA).

NCT ID: NCT05110326 Completed - Knee Osteoarthritis Clinical Trials

Ergon Technique Versus PNF Stretching on Hamstring Flexibility in Knee Osteoarthritis

Start date: January 10, 2022
Phase: N/A
Study type: Interventional

The study will be a randomized control trial and will be conducted in Pakistan Railway Hospital Rawalpindi. A sample of 60 participants will be taken. Patients will be divided into two groups (A&B) of 30 participants in each group by sealed envelope method. Hot pack will be applied to both groups for 15 minutes at the start of intervention. ERGON Technique(IASTM) will be applied to group A along with strengthening exercise. Proprioceptive Neuromuscular Facilitation (PNF) stretching will be given to group B along with strengthening exercise. A 35 minute session will be given to the patients and 3 sessions will be given once a week. Intervention will be given for 6 weeks. The outcome measure will be Visual analog Scale (VAS), Western Ontario and McMaster Universities Arthritis Index (WOMAC), and Active Knee Extension Test (AKE) will be measured at baseline and at the end of 6th week. Data will be analyzed by SPSS 22.

NCT ID: NCT05080075 Completed - Knee Osteoarthritis Clinical Trials

Platelet Rich Plasma in Knee Osteoarthritis

Start date: December 2, 2021
Phase: Early Phase 1
Study type: Interventional

In this study, the investigators will be performing intra-articular platelet rich plasma (PRP) injections for patients experiencing pain related to osteoarthritis of the knee. The investigators will be following clinical outcomes, and how they relate to concentrations of the PRP samples as well as following opioid and emergency room utilization pre and post-injection.

NCT ID: NCT05058235 Completed - Knee Osteoarthritis Clinical Trials

Comparison of Active Release Technique and Bent Leg Raise In Osteoarthritis.

Start date: November 14, 2020
Phase: N/A
Study type: Interventional

The objective of the study was to compare the effects of active release technique and bent leg raise on hamstring flexibility, functional outcomes, and pain in patients with knee osteoarthritis.

NCT ID: NCT05054686 Completed - Knee Osteoarthritis Clinical Trials

The Effect of Exercise Combination on Pain, Function and Proprioception in Knee Osteoarthritis

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

This study will include 3 different groups of intervention. First group of knee osteoarthritis patients will be applied both strengthening and 30 minutes bicycle exercises in the same session, 2 days strecthing exercises and 30 minutes walking will be given in seperate days as home program, Second group of knee osteoarthritis patients will be applied both stretching and 30 minutes bicycle exercises in the same session, strengthening exercises and 30 minutes walking will be given in seperate days as home program.Third group of knee osteoarthritis patients will be applied all stretching, strengthening and 30 minutes bicycle exercises in the same session, only 30 minutes walking will be given as home program. The primary outcome measures include the pain, function and the secondary outcome measures include the joint proprioception. The aim of this study is to investigate the effects on outcome measures increasing number of exercises in one session and to determine which exercise types are more suitable to prescribe as a home program.

NCT ID: NCT05050448 Completed - Knee Osteoarthritis Clinical Trials

Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain

Start date: August 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the usability of the ultrasound devices and common pain relief gel. The ability of the three treatment approaches to reduce pain, stiffness, and functionality as measured by NRS scale and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) will be evaluated.

NCT ID: NCT05038670 Completed - Knee Osteoarthritis Clinical Trials

Journey II vs Persona Knee Systems - RCT

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

This study compares and evaluates differences in patient-reported outcome, survivorship and radiological analysis between patients undergoing total knee arthroplasty with use of either Zimmer Biomet PERSONA Posterior Stabilized (PS) system and Smith&Nephew Journey II Bi-Cruciate Stabilized (BCS) system

NCT ID: NCT05036551 Completed - Knee Osteoarthritis Clinical Trials

Kinesiophobia, Pain, Functional Status and Self-Efficacy in Patients With Knee Osteoarthritis

Start date: March 20, 2018
Phase:
Study type: Observational

Objective: The aim of this study is to examine the relationship between kinesiophobia, pain, functional status and self efficacy in patients with knee osteoarthritis.

NCT ID: NCT05033977 Completed - Knee Osteoarthritis Clinical Trials

Center-based Physical Therapy and Home-based Physical Therapy After Platelet Rich Plasm Injection

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Osteoarthritis (OA) of the knee is a chronic disease characterized by pain, reduced range of motion, instability and effusion in the joint. Moreover, no study has investigated the effect of Platelet-rich Plasma (PRP) in comparison with that of a placebo injection in the same patient with bilateral knee OA. The purpose of this study was to compare the effectiveness of supervised physiotherapy and home exercises after PRP injection in patients with knee OA. The investigator hypothesized that the supervised physiotherapy program would be more effective in decreasing pain and improving muscle strength, physical function, and quality of life than home exercises following PRP injection in patients with knee OA. A total of 30 patients with complete follow-up to 6 weeks post-intervention; 17 patients randomized to the supervised exercise group and 13 patients randomized to the home exercise group. Subjects were recruited from who had radiographic evidence (Kellgren-Lawrence Grade II-III) of knee OA and ranged from 45 to 70 years of age. Measurements including pain during rest and activity, muscle strength assessment, self-estimated functions of the affected knee and functional performance tests for lower extremity strength were performed.