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Knee Osteoarthritis clinical trials

View clinical trials related to Knee Osteoarthritis.

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NCT ID: NCT05225480 Completed - Knee Osteoarthritis Clinical Trials

Reinforcement of Placebo Response in Knee Osteoarthritis: A Randomised Trial

Start date: April 21, 2022
Phase: N/A
Study type: Interventional

Saline intra-articular injections used as placebo treatments have been shown to provide pain relief in knee osteoarthritis (OA) It has further been shown that beneficial effects can be induced merely by having a conversation with a health professional. The aim of this study is to determine whether an individual conversation based on the individual's illness perception related to knee OA affects the response to an intra-articular treatment with saline in individuals with knee OA.

NCT ID: NCT05215678 Completed - Knee Osteoarthritis Clinical Trials

Characteristics of Patients Declining INKA Trial Participation

n-INKA
Start date: February 1, 2022
Phase:
Study type: Observational

The objective of this study is to compare baseline characteristics of overweight knee OA patients accepting vs. declining enrolment in the INKA trial (NCT05172843) to explore if enrolled patients differ systematically from the declining participants with respect to both measured as well as unmeasured baseline characteristics.

NCT ID: NCT05201040 Completed - Knee Osteoarthritis Clinical Trials

Evaluate the Safety and Effectiveness of Mannitol-combined Hyaluronan Supplement in the Treatment of Knee OA

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

To evaluate the effectiveness and safety of JETKNEE Synovial Fluid Supplement for alleviating pain of knee osteoarthritis (OA).

NCT ID: NCT05190588 Completed - Knee Osteoarthritis Clinical Trials

Efficacy of Mesotherapy in Patients With Knee Osteoarthritis

Start date: April 27, 2022
Phase: N/A
Study type: Interventional

Purpose: The investigators aimed to determine whether this treatment is effective on pain and function by applying mesotherapy treatment to patients followed up with gonarthrosis. Methods: This study is a prospective randomized controlled study. The research will be carried out between November 2021 and April 2022 in Pamukkale University Physical Medicine and Rehabilitation (PMR) After the approval of the Pamukkale University Faculty of Medicine Ethics Committee, 38 patients diagnosed with gonarthrosis will be divided into 2 groups using a table of random numbers. The first group will be the group that only applied quadriceps strength exercise and Mesotherapy will be applied to the second group along with quadriceps strength exercise. The data will be analyzed with the SPSS package program. Continuous variables will be given as mean ± standard deviation and categorical variables as numbers and percentages. parametric test Test of Significance of Difference Between Two Means in comparison of independent group differences when assumptions are met; When parametric test assumptions are not met, the Mann-Whitney U test will be used to compare independent group differences. In addition, the relationships between continuous variables will be examined with Spearman or Pearson correlation analyzes and the differences between categorical variables will be examined with Chi-square analysis. Since there is no similar study conducted and there is no possibility to conduct a pilot study, assuming that a moderate effect size will be obtained as a result of the power analysis made in the direction of the hypothetical expectations, it was taken to obtain 80% power with 95% confidence, and it was calculated that at least 38 people should be included in the study.

NCT ID: NCT05173649 Completed - Knee Osteoarthritis Clinical Trials

Calisthenic and Neuromuscular Training in Patients With Knee OA.

Start date: November 11, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to compare effects of calisthenics and neuromuscular training in patients with knee osteoarthritis.

NCT ID: NCT05169606 Completed - Knee Osteoarthritis Clinical Trials

Effect of Tissue Flossing, AIS, PNF on Hamstring Among Knee OA Patients

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

Tissue flossing has been known to produce results such as pain relief and improved range of motion, this technique might yield positive results in knee OA patients as well. These effects can further be compared with existing treatment method for treatment of hamstring such as Active isolated stretch and Proprioceptive Neuromuscular facilitation. This study will be among the first to carry out the technique of flossing in knee OA patients.

NCT ID: NCT05156216 Completed - Knee Osteoarthritis Clinical Trials

Comparative Effect of Two Educational Videos for People With Knee Osteoarthritis (vidEO)

vidEO
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Education is an important part of knee osteoarthritis management. The aim of education is to help people with knee osteoarthritis make the best choices for them in terms of their treatment and lifestyle behaviours. Traditional education that describes the condition simplistically in terms of the joint damage and describes the cause of osteoarthritis solely with respect to loading through the joint can lead to activity avoidance and pessimism about the future progression of symptoms. An alternative is to provide the information about knee osteoarthritis management with the aim of giving hope for the future and building motivation and confidence to be physically active. This study will compare two educational videos that cover the same topics but with a contrasting 'discourse'. The experimental video has an 'empowerment and participatory' discourse, while the comparator or control video has a typical 'disease and impairment' discourse. The experimental video minimises mention of joint damage and instead corrects misconceptions about knee osteoarthritis, addresses common barriers to physical activity and incorporates behaviour change techniques such as social learning and modelling of desired behaviours. In this randomised controlled trial, people who report a history of knee problems consistent with knee osteoarthritis will complete questionnaires to determine their self-efficacy for managing knee osteoarthritis pain and their fear of movement. The participants will also be asked about their expectations for the future, their level of motivation to be physically active, and their knowledge about knee osteoarthritis. Participants will then be allocated one of the videos and asked to watch it before repeating the questionnaires.

NCT ID: NCT05151627 Completed - Knee Osteoarthritis Clinical Trials

The Effectiveness of Kinesio Taping in Patients With Knee Osteoarthritis

Start date: June 17, 2020
Phase: N/A
Study type: Interventional

Knee osteoarthritis is the most common kind of arthritis that occurs due to degeneration of the joint articular cartilage, producing pain, stiffness, and impaired movement. Kinesio taping is a simple and inexpensive therapeutic procedure that can help with knee osteoarthritis symptoms. Kinesio taping is a high-stretch elastic adhesive material that allows the treated area to have free mobility. This technique was preferred by physical therapists for knee osteoarthritis rehabilitation because of its positive effects, such as decreased pain and increased mobility and muscular performance.

NCT ID: NCT05148416 Completed - Knee Osteoarthritis Clinical Trials

Effect of High Intensity Laser in Treatment of Myofascial Trigger Points in Symptomatic Knee Osteoarthritis

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

This study was conducted to investigate the effect of High intensity laser therapy( HILT) on pressure pain threshold, serum cortisol level, passive knee range of motion, and changes of functional disability in patients with active myofascial trigger points(MTrPs) pain associated wit knee osteoarthritis(OA) .

NCT ID: NCT05139030 Completed - Knee Osteoarthritis Clinical Trials

Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty

Start date: January 18, 2022
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare magnitude of postsurgical analgesic effect in different groups following a single dose of study drug when administered via adductor canal block in subjects undergoing primary unilateral total knee arthroplasty.