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Kidney Calculi clinical trials

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NCT ID: NCT05525130 Completed - Nephrolithiasis Clinical Trials

Study of the Administration of a Food Supplement in Patients With Lithiasis Treated With Extracorporeal Shock Wave Lithotripsy.

FAGOTRICIA
Start date: April 22, 2020
Phase: N/A
Study type: Interventional

The extracorporeal shock wave lithotripsy (ESWL) is the treatment of choice for most stones in any of their locations. It is about breaking the stone without surgically intervening on the patient and getting him to expel the fragments himself. It is thought that additional treatments to the ESWL could improve the success rate of ESWL for less favorable stones. The components of our authorized food supplement have shown an inhibitory effect in vitro on the growth of calcium oxalate monohydrate crystals, even in hightly supersaturared solutions. Also these components show an inhibitory effect on the growth of calcium phosphate crystals. To sum up, it reduces the formation, inhibits the growth and promotes the dissolution of calcium oxalate and calcium phosphate kidney stones. This is the reason why this experimental study aims to modify the size limit of the stones in the ESWL with adjuvant food supplement.

NCT ID: NCT05519150 Completed - Kidney Stones Clinical Trials

Donors With Nephrolithiasis at the Time of Transplant Evaluation (DONATE). Long Term Follow-up.

DONATE
Start date: September 2, 2022
Phase:
Study type: Observational

We believe that kidney donors with kidney stones accepted for a donation do not have an increased risk of loss of kidney function and will not be at increased risk of symptomatic kidney stone events compared to donors without a history of kidney stones.

NCT ID: NCT05516472 Not yet recruiting - Kidney Stones Clinical Trials

Fecal Microbiota Transplantation in Kidney Stone Patients

FMT IND
Start date: April 2024
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to measure the impact of Microbial Transplant Therapy (MTT) on 24-hour urine parameters in recurrent hypercalciuric and hyperoxaluric kidney stone formers.

NCT ID: NCT05511545 Completed - Kidney Calculi Clinical Trials

The Effect of Education Given to Patients on Pre- and Post-operative Anxiety and Preparation for Discharge

Start date: November 3, 2021
Phase: N/A
Study type: Interventional

The data of the randomized controlled experimental research were collected at Atatürk University Health Application and Research Hospital Urology Clinics between November 2021 and May 2022. The study sample consisted of 122 patients (61 in the training group, 61 in the control group) who were selected by the simple random sampling method and met the research inclusion criteria.

NCT ID: NCT05504512 Not yet recruiting - Kidney Diseases Clinical Trials

Percutaneous Nephroscopic Treatment of Parapelvic Cysts

Start date: November 30, 2022
Phase:
Study type: Observational

Background of the project: The surgical treatment of parapelvic cysts is currently less researched and there is no gold standard for surgery. Previously, in percutaneous nephrolithotomy, we found that fenestration and fenestration drainage in the simultaneous treatment of pararenal pelvis cysts under nephroscopic nephroscopic surgery has clear curative effect, less trauma, and quicker recovery. Objective: To clarify the safety, efficacy and long-term efficacy of percutaneous nephroscopy in the treatment of parapelvic cysts. Nature: Retrospective case cohort study. Basic research process: Retrospective collection of cases in our hospital who underwent percutaneous nephroscopy for the treatment of parapelvic cysts, and comparison of preoperative and postoperative cyst size changes and long-term efficacy.

NCT ID: NCT05460559 Recruiting - Stone, Kidney Clinical Trials

Endoscopic Combined Intrarenal Surgery Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones:

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare outcomes of endoscopic combined intrarenal surgery (ECIRS) with the multi-tract percutaneous nephrolithotomy for management of complex renal stones.

NCT ID: NCT05460247 Recruiting - Clinical trials for Kidney Stone Prevention

Protein Sources Urinary Stone Risk

Start date: October 30, 2022
Phase: N/A
Study type: Interventional

Prior studies have shown that the source of dietary protein can have a significant impact on urinary stone risk. However, whey and plant protein isolates have not been compared. This is an important distinction as protein supplements fortified foods are increasingly popular. Herein, we seek to investigate the effect of different protein supplements, in an otherwise identical diet, on urinary stone risk.

NCT ID: NCT05443932 Not yet recruiting - Urolithiasis Clinical Trials

Dapagliflozin and Hydrochlorothiazide in Recurring Kidney Stone Patients

Start date: March 4, 2024
Phase: Phase 4
Study type: Interventional

Current prevention strategies in patients with recurrence of kidney stones show especially in high-risk patients a diversely and in the long-term not successful outcome in a sustainable number of cases. Recent studies have revealed that Dapagliflozin has the potential to decrease risk and incidence of urolithiasis events especially in patients suffering from Diabetes. The investigators propose that Dapagliflozin has the potential to increase the metabolic situation of hyperoxaluric patients with recurrence of urolithiasis. The investigators therefore test whether Dapagliflozin can decrease the oxalate excretion compared to the current strategy with Hydrochlorothiazide. The study may open up a new way of preventing urolithiasis in patients with high-risk of recurring urolithiasis.

NCT ID: NCT05431049 Completed - Anesthesia Clinical Trials

Anesthesia Type on Percutaneous Nephrolithotomy in Aging Male

Start date: May 7, 2021
Phase:
Study type: Observational

The aim of this study is to compare the anesthesia methods in percutaneous nephrolithotomy in terms of safety and effectiveness in elderly men.

NCT ID: NCT05417568 Recruiting - Kidney Stones Clinical Trials

Oxalate-Driven Host Responses in Kidney Stone Disease

Start date: May 19, 2023
Phase: N/A
Study type: Interventional

This study is looking to understand the role of oxalate on kidney stone development and immunity. This study will enroll healthy participants and participants with calcium oxalate kidney stones (CaOx KS). Participants will be in this study for about 3 weeks, consume controlled diets, and provide blood and urine specimens.