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Kidney Calculi clinical trials

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NCT ID: NCT05161936 Terminated - Clinical trials for Recurrent Calcium Oxalate Kidney Stone Disease

A Study to Evaluate Lumasiran in Adults With Recurrent Calcium Oxalate Kidney Stone Disease and Elevated Urinary Oxalate Levels

Start date: January 27, 2022
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to evaluate the effect of lumasiran on the percent change in urinary oxalate excretion in patients with recurrent calcium oxalate kidney stone disease.

NCT ID: NCT04663269 Terminated - Surgery Clinical Trials

Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy

Start date: February 24, 2020
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if adding a spinal block (medicine that will numb parts of the body to block pain) along with standard pain control at the incision site will decrease the need for narcotics for pain management and decrease the percentage of patients requiring hospital admission for pain control during postoperative , in-hospital, care after a percutaneous nephrolithotomy (PCNL) (surgery to remove kidney stones), commonly called PERC.

NCT ID: NCT03656913 Terminated - Nephrolithiasis Clinical Trials

Validation of Low Dose CT for Diagnosis of Urolithiasis

Start date: November 30, 2018
Phase: N/A
Study type: Interventional

The investigators have developed an extremely low dose renal computed tomography (CT) protocol that on preliminary testing has an effective dose in the range of a single view abdominal radiograph. The investigators plan to test this exam in patients with known or suspected urolithiasis undergoing clinically indicated CT.

NCT ID: NCT02837393 Terminated - Urolithiasis Clinical Trials

Understanding the Urine Electrolyte Profile of the Individual Renal Unit

Start date: July 2016
Phase: N/A
Study type: Observational

The investigators objective is to determine if urinary electrolyte abnormalities exist in only one or both kidneys in participants with and without a history of kidney stones. To meet this objective, the investigators are going to take urine samples from each kidney at the time of kidney stone surgery. The samples will then be analyzed for absolute and relative differences in the concentrations of urine electrolytes, such as calcium.

NCT ID: NCT02752841 Terminated - Calculi Clinical Trials

The Effect of Vitamin D Repletion on Kidney Stone Risk

Start date: May 1, 2016
Phase: N/A
Study type: Interventional

Examine the effect of nutritional vitamin D repletion on urinary calcium excretion and kidney stone burden in calcium kidney stone formers

NCT ID: NCT02122341 Terminated - Kidney Stones Clinical Trials

Clinical Evaluation of BackStop in Patients Undergoing Ureteroscopic Lithotripsy

Start date: April 2014
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to evaluate BackStop, a polymer-based device that is intended to be used during ureteroscopic lithotripsy to prevent retrograde stone migration.

NCT ID: NCT02090439 Terminated - Kidney Stone Clinical Trials

Effectiveness of Silodosin in Medical Expulsive Therapy for Ureteral Pelvic Stone From 4 to 10 mm.

SiloMET
Start date: July 2014
Phase: Phase 3
Study type: Interventional

In the diagnosis of renal colic gallstone , in addition to clinical and biological factors, it is a key : medical imaging. Currently , the French recommendations require at least a couple of Abdomen radiography Without Preparation lying face (ASP ) associated with abdominal ultrasound . "The abdominopelvic CT scan without injection of contrast is the examination of choice. Current recommendations in the management of gallstone colic simply based on the joint use of analgesics , anti inflammatory drugs and control of water intake . The mechanism of analgesic action of this treatment is a decrease in the pressure in the cavities by decrease in diuresis and inflammation treatment of ureteral permitting passage of urine . ) The expulsive medical therapy remains under evaluation. The French Association of Urology does not recommend at this time for lack of evidence deemed sufficient. For foreign companies Urology (EAU , AUA) , the use of calcium channel blockers or alpha blockers in the treatment of symptomatic lower ureteral stones (4 to 10mm ) is recommended (grade 1A) . However, there are less formal studies of their effectiveness . Investigators wish to demonstrate the effectiveness of alpha in medical expulsive therapy for pelvic stones 4 to 10mm .

NCT ID: NCT01812772 Terminated - Kidney Stone Clinical Trials

The Effect of Ureteric Stent Tethers on Patient Symptoms and Urinary Infection

Start date: March 2013
Phase: N/A
Study type: Interventional

RESEARCH QUESTION Do ureteric stents with tethers, left in-situ for 1-2 weeks, increase the rate of stent bacterial colonization, urinary bacterial colonization and stent related lower urinary tract symptoms compared to stents without tethers? HYPOTHESIS We hypothesize that ureteral double-J stents with tethers increase the rate of stent bacterial colonization, but do not increase the rate of urinary bacterial colonization or stent related lower urinary tract symptoms compared to stents without tethers when left in-situ for 1-2 weeks.

NCT ID: NCT01420354 Terminated - Kidney Stones Clinical Trials

Can a Spot Urine Replace or Improve 24 Hour Urine Collections in Kidney Stone Patients

Start date: August 2009
Phase: N/A
Study type: Observational

This study will sought to determine if limited urine collections can provide similar or more informative data than standard 24-hour urine collections used to evaluate kidney stone formers.

NCT ID: NCT01371422 Terminated - Nephrolithiasis Clinical Trials

Trial Comparing the Effect of a Paravertebral Block on Pain Post Percutaneous Nephrolithotomy

Start date: August 2011
Phase: N/A
Study type: Interventional

This is a randomized control trial (meaning the selection is random as when flipping a coin) to assess the benefit of paravertebral blockade (PVB) in Percutaneous nephrolithotomy/nephrolithotripsy (PCNL) surgery.