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Ischemic Attack, Transient clinical trials

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NCT ID: NCT00846924 Active, not recruiting - Stroke Clinical Trials

30-Day Cardiac Event Monitor Belt for Recording Atrial Fibrillation After a Cerebral Ischemic Event

EMBRACE
Start date: May 2009
Phase: N/A
Study type: Interventional

Atrial fibrillation is the most common cardiac cause of ischemic stroke. Detecting atrial fibrillation after a stroke or TIA is critical because highly effective secondary stroke prevention therapy is available for individuals who are recognized to have atrial fibrillation. However, atrial fibrillation is likely under-diagnosed after stroke and TIA because atrial fibrillation is often difficult to detect as it is frequently paroxysmal and asymptomatic, and patients do not routinely undergo prolonged screening. The purpose of this study is to determine the diagnostic yield of a novel 30-day cardiac event monitor compared to a repeat 24-hour Holter monitor for detecting occult paroxysmal atrial fibrillation in patients with a recent ischemic stroke or TIA of undetermined etiology after completion of a standard clinical stroke work-up (including an initial negative Holter monitor.)

NCT ID: NCT00833989 Completed - Clinical trials for Ischaemic Attack, Transient

Safety Escalating Repeat IV, in Stroke Patients

MAG111539
Start date: July 8, 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to is to test increasing repeat doses of GSK249320 compared to placebo in patients with stroke.

NCT ID: NCT00816166 Terminated - Ischemic Stroke Clinical Trials

VISSIT Intracranial Stent Study for Ischemic Therapy

VISSIT
Start date: October 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The main objective of this study is to prospectively evaluate the safety, probable benefit, and effectiveness of the PHAROS Vitesse Neurovascular Stent System in a multicenter, randomized clinical trial. A secondary objective of this study is to evaluate the impact of stenting in the neurovasculature to treat cerebral ischemia on other outcomes such as hospital length of stay, charges, and costs.

NCT ID: NCT00744029 Completed - Stroke Clinical Trials

Reduction of Prehospital Delays in Stroke and Transient Ischaemic Attack (TIA)

BASS
Start date: February 2004
Phase: N/A
Study type: Interventional

In patients with acute stroke, systemic thrombolysis needs to be administered within three hours of symptom onset. The aim of the present study was to reduce prehospital delays in a population-based intervention.The intervention consisted of an educational letter indicating stroke symptoms and emphasizing the importance of calling the emergency medical services (EMS). The investigators additionally included a bookmark and sticker with the EMS telephone number. A total of 75,720 inhabitants received the intervention. Between 2004 and 2005, 741 patients with cerebrovascular events were admitted from the control areas (n=24) and 647 from the intervention areas (n=24).

NCT ID: NCT00738894 Completed - Stroke Clinical Trials

GORE® Septal Occluder Device for Patent Foramen Ovale (PFO) Closure in Stroke Patients

REDUCE
Start date: December 10, 2008
Phase: N/A
Study type: Interventional

The primary objective is to determine if patent foramen ovale (PFO) closure with the GORE® HELEX® Septal Occluder or GORE® CARDIOFORM Septal Occluder plus antiplatelet medical management is safe and effective and reduces the risk of recurrent stroke or imaging-confirmed transient ischemic attack (TIA) when compared to antiplatelet medical management alone in patients with a PFO and history of cryptogenic stroke or imaging-confirmed TIA. A co-primary objective is to demonstrate that medical management plus closure with the study device reduces the risk of new brain infarct compared to medical management alone.

NCT ID: NCT00724724 Recruiting - Stroke Clinical Trials

The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial

ESCAPE
Start date: August 2008
Phase: Phase 4
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of Butylphthalide Soft Capsules (En Bi Pu, NBP) in Secondary Prevention of Ischemic Stroke

NCT ID: NCT00715533 Completed - Acute Stroke Clinical Trials

3 Tesla (3T) Stroke Medical Radiologic Technology (MRT) for Examining Mismatch in 1000+

1000Plus
Start date: July 2008
Phase: N/A
Study type: Observational

The purpose of this study is to compare clinical and economic parameters of stroke patients who have received acute MRI imaging (test group) to patients who have received routine CT imaging (control group) in the clinical setting of acute stroke.

NCT ID: NCT00698763 Completed - Stroke Clinical Trials

Effects of Oral Levosimendan on Ambulatory Electrocardiographic Variables

Electro
Start date: August 2008
Phase: Phase 2
Study type: Interventional

The primary objective is to explore the safety of low doses of oral levosimendan in patients with recent history of an ischaemic cerebrovascular event (stroke or TIA). The main focus will be on the evaluation of proarrhythmic potential of the different dose regimens.

NCT ID: NCT00691314 Completed - Stroke Clinical Trials

Efficacy and Safety of Stent Implantation in Symptomatic Extra- and Intracranial Artery Stenosis

ESSCAS
Start date: June 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of stent implantation in patients with symptomatic extra- and intracranial artery stenosis and to determine its role in secondary prevention of ischemic stroke.

NCT ID: NCT00662818 Completed - Clinical trials for Cerebrovascular Accident

Telcagepant (MK-0974) Treatment of Migraine in Participants With Stable Vascular Disease (MK-0974-034)

Start date: March 17, 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of telcagepant in the treatment of acute migraine in participants with stable vascular disease. Acetaminophen/paracetamol (APAP) will be used as an active comparator in this study. The primary hypothesis of this study is that telcagepant 300 mg is superior to placebo.