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Intracranial Hemorrhages clinical trials

View clinical trials related to Intracranial Hemorrhages.

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NCT ID: NCT06018545 Active, not recruiting - Clinical trials for Acute Ischemic Stroke

AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation

AI-REACT
Start date: June 1, 2023
Phase:
Study type: Observational

This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838). The purpose of the study is to assess the impact of an Artificial Intelligence (AI) tool called qER 2.0 EU on the performance of readers, including general radiologists, emergency medicine clinicians, and radiographers, in interpreting non-contrast CT head scans. The study aims to evaluate the changes in accuracy, review time, and diagnostic confidence when using the AI tool. It also seeks to provide evidence on the diagnostic performance of the AI tool and its potential to improve efficiency and patient care in the context of the National Health Service (NHS). The study will use a dataset of 150 CT head scans, including both control cases and abnormal cases with specific abnormalities. The results of this study will inform larger follow-up studies in real-life Emergency Department (ED) settings.

NCT ID: NCT05626504 Active, not recruiting - Stroke Clinical Trials

Outcome Study of the Pipeline Embolization Device With Vantage Technology in Unruptured Aneurysms

PEDVU
Start date: October 27, 2022
Phase:
Study type: Observational

In this project the investigators study the safety and efficacy of the pipeline embolization device with vantage technology in treatment of unruptured brain aneurysms

NCT ID: NCT05159219 Active, not recruiting - Clinical trials for Intracranial Hemorrhages

Colchicine for the Prevention of Vascular Events After an Acute Intracerebral Hemorrhage

CoVasc-ICH
Start date: August 4, 2022
Phase: Phase 2
Study type: Interventional

The overall goal is to establish the safety and efficacy of colchicine in ICH patients for the prevention of major cardiovascular events and brain injury. Colchicine for the prevention of vascular events after an acute intracerebral hemorrhage (CoVasc-ICH) is a vanguard pilot trial designed to obtain the factual feasibility prerequisites essential for the planning, design, funding and execution of a subsequent phase III trial.

NCT ID: NCT05127941 Active, not recruiting - Clinical trials for Intracranial Hemorrhages

Andexanet Alfa: Non-interventional Study in Stroke Units in Germany (DE)

ASTRO-DE
Start date: December 8, 2021
Phase:
Study type: Observational

The multicenter, prospective, observational, non-interventional study conducted in German Stroke Units is investigating patients with intracranial hemorrhage (ICH) under effective anticoagulation with rivaroxaban or apixaban. The aim of the study is to analyze under routine conditions wether the volume increase of ICH under treatment with rivaroxaban and apixaban can be reduced with the antidote andexanet alfa. Thus, data of patients under effective treatment with rivaroxaban or apixaban and treated with andexanet alfa at baseline will be assessed at the time of onset of ICH, during the hospital stay and during a follow-up by telephone at 30 and 90 days after hospital discharge. The main objective is defined as the change in size or volume of the hematoma by computed tomography (CT) or magnetic resonance imaging (MRI) in patients with ICH under effective treatment with rivaroxaban and apixaban, who are treated with andexanet alfa. Further objectives comprise evaluations concerning the functional status according to modified Rankin Scale (mRS), changes in the National Institutes of Health Stroke Scale (NIHSS), and occurrences of ICH or new intraventricular bleeding as well as mortality rates.

NCT ID: NCT04337697 Active, not recruiting - Stroke Clinical Trials

Neonatal Seizure Registry - Developmental Functional EValuation

NSR-DEV
Start date: March 15, 2020
Phase:
Study type: Observational [Patient Registry]

The NSR-DEV study is a longitudinal cohort study of around 280 Neonatal Seizure Registry participants that aims to evaluate childhood outcomes after acute symptomatic neonatal seizures, as well as examine risk factors for developmental disabilities and whether these are modified by parent well-being.

NCT ID: NCT03905031 Active, not recruiting - Clinical trials for Traumatic Brain Injury

Defining the Operating Characteristics of NIRS in the Diagnosis of Pediatric Traumatic Intracranial Hemorrhage

Start date: April 15, 2019
Phase: N/A
Study type: Interventional

In this study, investigators look at a different type of technology that might help to avoid having to perform CT scans in certain patients suspected of having a head injury. Near-infrared spectroscopy (NIRS) uses a specific light wavelength to determine if there is bleeding into the head as a result of trauma. Investigators will study NIRS, using a device called the Infrascanner model 2000, to determine if it is as good at detecting bleeding in the head as CT scan, which is the current gold standard. Investigators will try to determine if NIRS can rule in or rule out bleeding into the head, and perhaps this can help to avoid subjecting these youth to the potentially harmful effects of radiation. Investigators will also study how easy it is to use NIRS so that it might become a standard part of the workup for children with suspected head injury.

NCT ID: NCT03359434 Active, not recruiting - Blood Pressure Clinical Trials

Blood Pressure Measurement Methods and Prediction of Intracranial Hemorrhage After Thrombectomy in Stroke

BP-METROLOGY
Start date: December 5, 2018
Phase: N/A
Study type: Interventional

A monocentric, non-randomized, prospective study in which each patient is his/her own control. The study investigates 2 methods of blood pressure measurement, within the first 24 hours after reperfusion, i) Continuous measurement of blood pressure with the Clearsight device (Edwards) and ii) intermittent blood pressure measurements with cuff.

NCT ID: NCT03342664 Active, not recruiting - Clinical trials for Intracerebral Hemorrhage

MIND: Artemis in the Removal of Intracerebral Hemorrhage

Start date: February 7, 2018
Phase: N/A
Study type: Interventional

The primary objective of this multicenter randomized controlled study is to compare the safety and efficacy of minimally invasive hematoma evacuation with the Artemis Neuro Evacuation Device to best medical management for the treatment of intracerebral hemorrhage (ICH).

NCT ID: NCT02673788 Active, not recruiting - Clinical trials for Intracranial Hemorrhages

Follow-Up Study of Safety of Pneumostem® in Premature Infants With Intraventricular Hemorrhage

Start date: January 2016
Phase:
Study type: Observational

This is a follow-up study of the open label, single-center, phase I clinical trial to evaluate the safety of Pneumostem® in premature infants with Intraventricular hemorrhage.

NCT ID: NCT02483169 Active, not recruiting - Brain Ischemia Clinical Trials

PreventIon of IMT Progression in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage-IMT Study

PICASSO-IMT
Start date: June 2009
Phase: Phase 4
Study type: Interventional

Through this study, the investigators are to prove that Cilostazol effectively prevent progression of intima-medial thickness in ischemic stroke patients with high risk of cerebral hemorrhage, along with no significant increase in the risk of occurrence of hemorrhagic side effects. The primary hypothesis of this study is; Cilostazol alone or with probucol will reduce the progression of intima-medial thickness compared to aspirin in the ischemic stroke patients with symptomatic or asymptomatic old cerebral hemorrhage.